{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:21:21Z","timestamp":1756383681659},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Pyogenic liver abscess (PLA) is a process with significant morbidity and mortality and is a rare complication in an aisled way in patients with autosomal dominant polycystic kidney disease (ADPKD). In addition to hepatic cyst infection, intracystic hemorrhage is another complication seen in ADPKD patients; however, the liver parenchyma itself remains normal. A PLA located in normal liver tissue in these kinds of patients has not been previously reported. <jats:italic>Fusobacterium nucleatum<\/jats:italic> is an anaerobic bacterium with rare involvement other than in periodontal infections. A 58\u2010year\u2010old Caucasian male, who was on hemodialysis treatment from July 2004 due to end\u2010stage renal disease secondary to ADPKD, was admitted with fever, rigor, chills, weakness, and abdominal pain of 10\u2003days duration. During that time, ciprofloxacin 500\u2003mg, twice daily, gentamycin 80\u2003mg\/48\u2003h, and vancomycin 1\u2003g\/week, were prescribed, but treatment was interrupted by hospitalization. Physical examination on admission revealed that the patient had a fever of 39.8\u00b0C, pallor, chills, right upper quadrant abdominal pain, and hepatosplenomegaly. Abdominal ultrasound revealed a 5.3\u2003cm diameter collection with irregular configuration located in the caudate lobe. Abdominal computed tomography (CT) showed a large multiloculated hepatic collection. The PLA was managed with antibiotics (metronidazole) and continuous catheter drainage (8Fr drainage catheters [Abocath\u2010T, Abbott, Sligo, Ireland]) into the abscess. Fluid culture was positive for <jats:italic>F.\u2003nucleatum<\/jats:italic>. Complete remission was obtained after 12\u2003days without complications. We describe a PLA by <jats:italic>F.\u2003nucleatum<\/jats:italic>, in a very rare location in an ADPKD patient undergoing hemodialysis without complicated cysts, managed with antibiotics and percutaneous drainage with satisfactory resolution.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2007.00548.x","type":"journal-article","created":{"date-parts":[[2008,2,2]],"date-time":"2008-02-02T04:34:52Z","timestamp":1201926892000},"page":"91-95","source":"Crossref","is-referenced-by-count":15,"title":["A Case Report of a Pyogenic Liver Abscess Caused by Fusobacterium Nucleatum in a Patient With Autosomal Dominant Polycystic Kidney Disease Undergoing Hemodialysis"],"prefix":"10.1111","volume":"12","author":[{"given":"Secundino","family":"Cigarr\u00e1n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Neches","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Lamas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Garc\u00eda\u2010Trio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesus","family":"Saavedra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2002.02787.x"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/95.12.797"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2004.03368.x"},{"key":"e_1_2_4_5_2","first-page":"257","article-title":"Hepatobiliary infections","volume":"17","author":"Rockey DC","year":"2001","journal-title":"Gastroenterol"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200410000-00019"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.1.131"},{"key":"e_1_2_4_8_2","first-page":"1","volume-title":"Advances in Nephrology","author":"Grunfeld JP","year":"1985"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)65154-4"},{"key":"e_1_2_4_10_2","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1007\/s00330-002-1398-y","article-title":"CT\u2010guided percutaneous drainage of intra\u2010abdominal abscesses: APACHE III store stratification of 1\u2010year results","volume":"12","author":"Betsch A","year":"2002","journal-title":"Eur Radiol"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/109629600321254"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(03)00088-9"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00012258"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198409000-00010"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1622.1999.01523.x"},{"key":"e_1_2_4_16_2","first-page":"530","volume-title":"Polycystic Kidney Disease","author":"Elzinga LW","year":"1996"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.9.1.55"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01658732"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(03)00088-9"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-39-4-246"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100002717"},{"key":"e_1_2_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9270(02)04776-7"},{"key":"e_1_2_4_23_2","first-page":"407","article-title":"Pyogenic hepatic abscess: results of current management","volume":"61","author":"Hashimoto L","year":"1995","journal-title":"Am Surg"},{"key":"e_1_2_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(95)71058-2"},{"key":"e_1_2_4_25_2","first-page":"1067","article-title":"Percutaneous catheter drainage of infected intra\u2010abdominal fluid collections. 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