{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T22:51:04Z","timestamp":1767912664573,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T00:00:00Z","timestamp":1217894400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> We herein report the case of a 73\u2010year\u2010old woman with steroid and cyclosporine resistant collapsing focal segmental glomerulosclerosis (FSGS) whose refractory proteinuria and hypoproteinemia were controlled with low\u2010density lipoprotein apheresis (LDL\u2010A). She was initially treated with steroid therapy, including methylprednisolone pulse and cyclosporine therapy. However, her hypoproteinemia, accompanied with renal insufficiency, persisted despite these therapies. We treated her using LDL\u2010A and found improvement in her urine protein excretion, hyperlipidemia, hypoproteinemia, and renal function as a result of this treatment. This suggests that LDL\u2010A may therefore be an effective therapy for nephrotic syndrome due to collapsing FSGS.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2008.00596.x","type":"journal-article","created":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T06:47:20Z","timestamp":1217918840000},"page":"333-336","source":"Crossref","is-referenced-by-count":8,"title":["A Case Report of Nephrotic Syndrome Due to Collapsing Focal Segmental Glomerulosclerosis Treated With Low\u2010density Lipoprotein Apheresis"],"prefix":"10.1111","volume":"12","author":[{"given":"Motoaki","family":"Miyazono","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Tomiyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoya","family":"Kishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanobu","family":"Sakemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Sanai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Node","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,8,5]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000160"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(86)80052-X"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.493"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001903"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.185"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00041552-200103000-00006"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.07130.x"},{"key":"e_1_2_4_9_2","first-page":"1","article-title":"LDL adsorption improves the response of focal glomerulosclerosis to corticosteroid therapy","volume":"50","author":"Yokoyama K","year":"1998","journal-title":"Clin Nephrol"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.5414\/CNP67341"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2004.09.013"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.5414\/CNP60275"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-0968.2002.00458.x"},{"key":"e_1_2_4_14_2","first-page":"S27","article-title":"Role of dietary lipids and renal eicosanoids on the progression of renal disease","volume":"27","author":"Klahr S","year":"1989","journal-title":"Kidney Int Suppl"},{"key":"e_1_2_4_15_2","doi-asserted-by":"crossref","first-page":"S210","DOI":"10.1038\/sj.ki.4495441","article-title":"Rapid normalization of interleukin\u20108 production after low\u2010density lipoprotein apheresis in steroid\u2010resistant nephrotic syndrome","volume":"71","author":"Sakurai M","year":"1999","journal-title":"Kidney Int Suppl"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00769.x"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(99)70215-5"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050028"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-006-0312-2"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-9987.2008.00596.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-9987.2008.00596.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T14:05:18Z","timestamp":1697292318000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-9987.2008.00596.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1111\/j.1744-9987.2008.00596.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-9987.2008.00596.x","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}