{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:39:11Z","timestamp":1789609151220,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,10,2]],"date-time":"2008-10-02T00:00:00Z","timestamp":1222905600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study describes the efficacy of plasmapheresis for the treatment of toxic epidermal necrolysis (TEN), as reported in Japan. TEN patients treated with plasmapheresis were collected from Japanese literature. The type of plasmapheresis, number of sessions, efficacy of plasmapheresis, and present outcome were examined. Forty\u2010seven TEN patients treated with plasmapheresis have been reported in the literature: 19 men and 28 women with ages ranging from 1 to 96\u2003years (mean 50.3\u2003years). Twenty\u2010five of these treatments included simple plasma exchange (PE), 13 included double filtration plasmapheresis (DFPP), and one included PE and DFPP. The number of plasmapheresis sessions ranged from 1 to 6 and the mean number of sessions was 3.1. The efficacy of plasmapheresis for the treatment of TEN was as follows: excellent, 30 cases; good, 8 cases; fair, 3 cases; no effect, 5 cases; and unknown, 1 case. The rate of effectiveness was 80.9%; eleven patients died; and the mortality rate was 23.4%. In summary, plasmapheresis, including both PE and DFPP, were found to be effective treatments for Japanese patients with TEN, who had been unresponsive to corticosteroids, and for those who show severe clinical manifestations.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2008.00609.x","type":"journal-article","created":{"date-parts":[[2008,10,2]],"date-time":"2008-10-02T11:04:16Z","timestamp":1222945456000},"page":"355-359","source":"Crossref","is-referenced-by-count":44,"title":["Status of Plasmapheresis for the Treatment of Toxic Epidermal Necrolysis in Japan"],"prefix":"10.1111","volume":"12","author":[{"given":"Hiromichi","family":"Yamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Takamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,10,2]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1967.tb11434.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1994.tb00362.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.1998.tb00094.x"},{"key":"e_1_2_6_5_2","first-page":"1267","article-title":"A case of toxic epidermal necrolysis treated successfully with double filtration plasmapheresis","volume":"111","author":"Kaneko C","year":"2001","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_6_2","first-page":"968","article-title":"A case of toxic epidermal necrolysis caused by allopurinol","volume":"116","author":"Okuyama Y","year":"2006","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1001\/archderm.1985.01660120074023","article-title":"Plasmapheresis in severe drug\u2010induced toxic epidermal necrolysis","volume":"121","author":"Kamanabroo D","year":"1985","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1177\/039139889101401006","article-title":"Plasma exchange (PE) treatment in drug\u2010induced toxic epidermal necrolysis (TEN)","volume":"14","author":"Sakellario G","year":"1991","journal-title":"Artifi Organs"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00192.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70497-4"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051063"},{"key":"e_1_2_6_12_2","first-page":"952","article-title":"A case of toxic epidermal necrolysis treated successfully with double filtration plasmapheresis","volume":"98","author":"Hanada K","year":"1988","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_13_2","first-page":"47","volume-title":"Comprehensive Handbook of Clinical Dermatology","author":"Iijima M","year":"2004"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-924.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512143332404"},{"key":"e_1_2_6_16_2","first-page":"1581","article-title":"Clinical study of deceased cases of toxic epidermal necrolysis (TEN) in Japan; Comparative study with surviving cases of TEN and with deceased cases of Stevens\u2013Johnson syndrome","volume":"109","author":"Aihara M","year":"1999","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_17_2","first-page":"145","article-title":"Severe adverse drug reaction and drug eruption in Japan","volume":"25","author":"Nanko H","year":"2003","journal-title":"Pract Dermatol"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.1.33"},{"key":"e_1_2_6_19_2","first-page":"259","article-title":"Lyell's syndrome: treatment by plasma exchange","volume":"5","author":"Gerard A","year":"1984","journal-title":"Plasma Ther Transfus Technol"},{"key":"e_1_2_6_20_2","first-page":"433","article-title":"Long term remission successfully achieved in severe types of pemphigus vulgaris and bullous pemphigus by the use of plasmapheresis","volume":"3","author":"Takamori K","year":"1993","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-0968.2002.00409.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.282.5388.490"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64284-8"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-9987.2008.00609.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-9987.2008.00609.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T02:07:45Z","timestamp":1697249265000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-9987.2008.00609.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1111\/j.1744-9987.2008.00609.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-9987.2008.00609.x","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}