{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T04:46:22Z","timestamp":1697345182781},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,5,30]],"date-time":"2011-05-30T00:00:00Z","timestamp":1306713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Citrate anticoagulation has not yet been described for hemodiafiltration (HDF) with high cut\u2010off (HCO) membranes, which can be used in the treatment of cast nephropathy secondary to multiple myeloma. A 57\u2010year\u2010old male patient with multiple myeloma and acute renal failure was treated with HDF using a HCO membrane (Theralite) each or every other day. Due to thrombocytopenia, citrate anticoagulation was done for the first 7\u2003h, and anticoagulant\u2010free HDF was performed for the last hour to avoid citrate accumulation. Magnesium, phosphate, and albumin were measured after 3, 6, and 8\u2003h, and were replaced as necessary. Thirty\u2010two post\u2010dilution HDF procedures (8\u2003h each, infusate 24\u2003L) were performed with blood flow at 300\u2013330\u2003mL\/h; sodium citrate 4% was infused at 300\u2003mL\/h and 1\u2003mol\/L calcium chloride was infused at a mean rate of 14.6\u2003\u00b1\u20031.1\u2003mL\/h. Calcium\u2010free dialysate\/infusate was used. Ionized calcium was stable (1.10\u2003\u00b1\u20030.06 before and 1.08\u2003\u00b1\u20030.06\u2003mmol\/L after HDF). Magnesium was stable (0.67\u2003\u00b1\u20030.12 before and 0.68\u2003\u00b1\u20030.05\u2003mmol\/L after HDF), with an average 390\u2003\u00b1\u2003180\u2003mg per procedure, substituted orally. There was no metabolic alkalosis or hypernatremia after the procedures, and no significant clotting was noted. The total\/ionized calcium ratio (1.87\u2003\u00b1\u20030.22 before vs. 1.56\u2003\u00b1\u20030.20 after 6\u2003h) and the corrected\/ionized calcium ratio (2.02\u2003\u00b1\u20030.21 before vs. 1.88\u2003\u00b1\u20030.27 after 6\u2003h) decreased during HDF, indicating no citrate accumulation. Citrate anticoagulation was effectively performed during 8\u2003h of HCO membrane HDF. There were no side effects of citrate anticoagulation, nor were any signs of citrate accumulation noted.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2011.00952.x","type":"journal-article","created":{"date-parts":[[2011,6,14]],"date-time":"2011-06-14T19:40:33Z","timestamp":1308080433000},"page":"283-286","source":"Crossref","is-referenced-by-count":4,"title":["Citrate Anticoagulation During Post\u2010Dilution Hemodiafiltration With a High Cut\u2010Off (Theralite) Membrane"],"prefix":"10.1111","volume":"15","author":[{"given":"Janko","family":"Kova\u010d","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakob","family":"Guben\u0161ek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreja Marn","family":"Pernat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jadranka","family":"Buturovi\u0107\u2010Ponikvar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u0161tjan","family":"Kersni\u010d","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u017ee","family":"Pretnar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Ponikvar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,5,30]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006080821"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04590908"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1594.1998.06072.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00671.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200104000-00010"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2009.00729.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/039139880803100408"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.07.041"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000084871.76568.E6"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1774-9987.2005.00267.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2007.00459.x"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-9987.2011.00952.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-9987.2011.00952.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T10:28:58Z","timestamp":1697279338000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-9987.2011.00952.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,30]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1111\/j.1744-9987.2011.00952.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-9987.2011.00952.x","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,30]]}}}