{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:08:35Z","timestamp":1759482515160},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T00:00:00Z","timestamp":1344297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Residual renal function preservation in patients with renal failure has been shown to be related to better outcomes not only in the pre\u2010dialysis phase but also after hemodialysis initiation. However, the effect of factors such as antihypertensive agents on residual renal function preservation has not been investigated adequately in prevalent hemodialysis patients. This study examined factors related to the rate of residual renal function preservation in 1\u2010year hemodialysis patients who had residual renal function. We enrolled 191 consecutive maintenance hemodialysis patients who underwent hemodialysis for 1\u2003year and maintained a urine output of more than 200\u2003mL\/day, to assess residual renal function loss. The rate of residual renal function loss was 19.9%. Multivariate analysis using residual renal function as the dependent variable revealed significant independent relationships with renin\u2010angiotensin system inhibitor use (hazard ratio, 0.438; <jats:italic>P<\/jats:italic>\u2003=\u20030.027), history of cardiovascular disease (hazard ratio, 2.475; <jats:italic>P<\/jats:italic>\u2003=\u20030.024), and rate of weight gain between dialysis sessions (hazard ratio, 1.348; <jats:italic>P<\/jats:italic>\u2003=\u20030.013). No relationship was observed with calcium channel blocker use. Renin\u2010angiotensin system inhibitor use, rate of body weight gain between dialysis sessions, and cardiovascular diseases are independently associated with residual renal function preservation in patients with residual renal function after 1\u2003year of hemodialysis. A further intervention study is required to investigate whether treatment with renin\u2010angiotensin system inhibitors and suppression of body weight gain preserves residual renal function for a longer time in hemodialysis patients.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2012.01087.x","type":"journal-article","created":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T06:31:14Z","timestamp":1344321074000},"page":"554-559","source":"Crossref","is-referenced-by-count":12,"title":["Effect of Renin\u2010Angiotensin System Inhibitor on Residual Glomerular Filtration Rate in Hemodialysis Patients"],"prefix":"10.1111","volume":"16","author":[{"given":"Yoko","family":"Itoh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Fujikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Toya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Mitsuhashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimasa","family":"Ohnishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhito","family":"Hirawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Umemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,8,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67814-2"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000024416.33113.0A"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011489"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp056"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042167"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000180589"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V12102158"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1177\/089686080002000411","article-title":"Residual renal function in a large cohort of peritoneal dialysis patients: change over time, impact on mortality and nutrition","volume":"20","author":"Shemin D","year":"2000","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.25198"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000117976.29592.93"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V113556"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00505.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1975.98"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1093\/ndt\/10.12.2274","article-title":"Time course of inulin and creatinine clearance in the interval between two haemodialysis treatments","volume":"10","author":"van Olden RW","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00090-1"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.3317\/jraas.2004.032"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604113341502"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)04433-X"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M601320200"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-1391"},{"key":"e_1_2_6_22_2","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/089686080002000410","article-title":"Rate of decline of residual renal function in patients on continuous peritoneal dialysis and factors affecting it","volume":"20","author":"Singhal MK","year":"2000","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/089686080802803s35"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1159\/000187976"},{"key":"e_1_2_6_25_2","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1177\/089686080902900110","article-title":"Subclinical peripheral artery disease in patients undergoing peritoneal dialysis: risk factors and outcome","volume":"29","author":"Liu JH","year":"2009","journal-title":"Perit Dial Int"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-9987.2012.01087.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-9987.2012.01087.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T05:08:30Z","timestamp":1697260110000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-9987.2012.01087.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,7]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/j.1744-9987.2012.01087.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-9987.2012.01087.x","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,7]]}}}