{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:06:24Z","timestamp":1787015184344,"version":"build-2736575974"},"reference-count":118,"publisher":"Tech Science Press","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1353,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Congenit Heart Dis"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1111\/j.1747-0803.2011.00601.x","type":"journal-article","created":{"date-parts":[[2011,12,19]],"date-time":"2011-12-19T00:07:55Z","timestamp":1324253275000},"page":"312-323","source":"Crossref","is-referenced-by-count":30,"title":["Pediatric Coronary Allograft Vasculopathy-A Review of Pathogenesis and Risk Factors"],"prefix":"10.32604","volume":"7","author":[{"given":"Kurt R.","family":"Schumacher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Gajarski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Urschel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"17807","published-online":{"date-parts":[[2011,12,18]]},"reference":[{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0022-3476(05)82871-9","article-title":"Coronary arteriosclerosis in pediatric heart transplant survivors: limitation of long-term survival","volume":"116","author":"Pahl","year":"1990","journal-title":"J Pediatr"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1432-2277.2005.00255.x","article-title":"Cardiac allograft vasculopathy in pediatric heart transplant recipients","volume":"19","author":"Hathout","year":"2006","journal-title":"Transpl Int"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1399-0012.2010.01307.x","article-title":"Cardiac allograft vasculopathy: current knowledge and future direction","volume":"25","author":"Colvin-Adams","year":"2011","journal-title":"Clin Transplant"},{"issue":"3","key":"10.1111\/j.1747-0803.2011.00601.x-BIB4|cit4","first-page":"S38","article-title":"Histopathology of graft coronary disease","volume":"11","author":"Billingham","year":"1992","journal-title":"J Heart Lung Transplant"},{"issue":"4","key":"10.1111\/j.1747-0803.2011.00601.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0735-1097(95)00564-1","article-title":"Dichotomous pattern of coronary atherosclerosis 1 to 9 years after transplantation: insights from systematic intravascular ultrasound imaging","volume":"27","author":"Tuzcu","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.healun.2010.08.009","article-title":"The Registry of the International Society for Heart and Lung Transplantation: thirteenth official pediatric heart transplantation report-2010","volume":"29","author":"Kirk","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB7|cit7","volume-title":"Allograft Vasculopathy: Detection, Risk Factors, Natural History, and Treatment","author":"Pahl","year":"2007"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.athoracsur.2010.03.043","article-title":"Donor age is associated with chronic allograft vasculopathy after adult heart transplantation: implications for donor allocation","volume":"90","author":"Nagji","year":"2010","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1111\/j.1747-0803.2011.00601.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1016\/S0041-1345(02)03283-9","article-title":"Activation of proinflammatory mediators in heart transplants from brain-dead donors: evidence from a model of chronic rat cardiac allograft rejection","volume":"34","author":"Wilhelm","year":"2002","journal-title":"Transplant Proc"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/00007890-199608150-00005","article-title":"Changes in organ perfusion after brain death in the rat and its relation to circulating catecholamines","volume":"62","author":"Herijgers","year":"1996","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/CIRCRESAHA.109.194977","article-title":"Complement-dependent inflammation and injury in a murine model of brain dead donor hearts","volume":"105","author":"Atkinson","year":"2009","journal-title":"Circ Res"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1097\/00007890-200206150-00027","article-title":"Brain death impairs coronary endothelial function","volume":"73","author":"Szabo","year":"2002","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.healun.2004.01.021","article-title":"Endothelial activation in the transplanted human heart from organ retrieval to 3 months after transplantation: an observational study","volume":"24","author":"Stoica","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/01.TP.0000080981.90718.EB","article-title":"Cardiac allograft vasculopathy: central role of endothelial injury leading to transplant \u201catheroma.\u201d","volume":"76","author":"Valantine","year":"2003","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.trim.2008.03.002","article-title":"Immunologic targets in the etiology of allograft vasculopathy: endothelium versus media","volume":"19","author":"Currie","year":"2008","journal-title":"Transpl Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1749-8090-5-52","article-title":"Neutrophil mediated smooth muscle cell loss precedes allograft vasculopathy","volume":"5","author":"King","year":"2010","journal-title":"J Cardiothorac Surg"},{"issue":"6","key":"10.1111\/j.1747-0803.2011.00601.x-BIB17|cit17","first-page":"S142","article-title":"Cardiac allograft vasculopathy: the central pathogenetic role of ischemia-induced endothelial cell injury","volume":"14","author":"Day","year":"1995","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.trim.2005.02.006","article-title":"Aortic allograft vasculopathy is mediated by CD8(+) T cells in Cyclosporin A immunosuppressed mice","volume":"15","author":"Vessie","year":"2005","journal-title":"Transpl Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1097\/TP.0b013e3181d3f271","article-title":"B cells and plasma cells in coronaries of chronically rejected cardiac transplants","volume":"89","author":"Wehner","year":"2010","journal-title":"Transplantation"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/labinvest.3700215","article-title":"The role of shear stress in the pathogenesis of atherosclerosis","volume":"85","author":"Cunningham","year":"2005","journal-title":"Lab Invest"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1136\/hrt.2009.187898","article-title":"Coronary endothelial dysfunction is associated with a reduction in coronary artery compliance and an increase in wall shear stress","volume":"96","author":"Takumi","year":"2010","journal-title":"Heart"},{"issue":"6","key":"10.1111\/j.1747-0803.2011.00601.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"H3148","DOI":"10.1152\/ajpheart.01281.2006","article-title":"Effects of transmural pressure and wall shear stress on LDL accumulation in the arterial wall: a numerical study using a multilayered model","volume":"292","author":"Sun","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2","key":"10.1111\/j.1747-0803.2011.00601.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.pcl.2010.01.018","article-title":"Immunosuppression armamentarium in 2010: mechanistic and clinical considerations","volume":"57","author":"Urschel","year":"2010","journal-title":"Pediatr Clin North Am"},{"issue":"5","key":"10.1111\/j.1747-0803.2011.00601.x-BIB24|cit24","first-page":"II224","article-title":"Decreasing incidence of coronary disease in pediatric cardiac transplant recipients using increased immunosuppression","volume":"88","author":"Addonizio","year":"1993","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.healun.2005.02.002","article-title":"Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients","volume":"24","author":"Eisen","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1056\/NEJMoa022171","article-title":"Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients","volume":"349","author":"Eisen","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1161\/01.CIR.0000070421.38604.2B","article-title":"Use of rapamycin slows progression of cardiac transplantation vasculopathy","volume":"108","author":"Mancini","year":"2003","journal-title":"Circulation"},{"issue":"5","key":"10.1111\/j.1747-0803.2011.00601.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1016\/j.athoracsur.2007.05.095","article-title":"Influence of pretransplant panel-reactive antibody on outcomes in 8160 heart transplant recipients in recent era","volume":"84","author":"Nwakanma","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1399-3046.2005.00425.x","article-title":"Anti-HLA alloantibodies in pediatric solid organ transplantation","volume":"10","author":"Girnita","year":"2006","journal-title":"Pediatr Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.humimm.2004.12.008","article-title":"Impact of ELISA-detected anti-HLA antibodies on pediatric cardiac allograft outcome","volume":"66","author":"Di Filippo","year":"2005","journal-title":"Hum Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.healun.2007.03.015","article-title":"Survival in allosensitized children after listing for cardiac transplantation","volume":"26","author":"Feingold","year":"2007","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1111\/j.1747-0803.2011.00601.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"S232","DOI":"10.1016\/j.healun.2008.11.486","article-title":"Association between donor-specific HLA antibodies and adverse outcome following paediatric cardiac transplantation","volume":"28","author":"Irving","year":"2009","journal-title":"J Heart Lung Transplant"},{"issue":"2","key":"10.1111\/j.1747-0803.2011.00601.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"S232","DOI":"10.1016\/j.healun.2008.11.485","article-title":"Impact of panel-reactive antibodies on long-term outcome in pediatric heart transplant patients: an analysis of the united network of organ sharing database","volume":"28","author":"Rossano","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1600-6143.2009.02877.x","article-title":"Absence of donor-specific anti-HLA antibodies after ABO-incompatible heart transplantation in infancy: altered immunity or age?","volume":"10","author":"Urschel","year":"2010","journal-title":"Am J Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0735-1097(00)00701-4","article-title":"The medium-term findings in coronary arteries by intravascular ultrasound in infants and children after heart transplantation","volume":"36","author":"Kuhn","year":"2000","journal-title":"J Am Coll Cardiol"},{"issue":"25","key":"10.1111\/j.1747-0803.2011.00601.x-BIB36|cit36","first-page":"A13877","article-title":"Abstract 13877: has late rejection decreased in pediatric heart transplantation in the current era? A multi-institutional study","volume":"122","author":"Ameduri","year":"2010","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.healun.2004.03.021","article-title":"The impact and outcome of transplant coronary artery disease in a pediatric population: a 9-year multi-institutional study","volume":"24","author":"Pahl","year":"2005","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0735-1097(00)01037-8","article-title":"Late rejection is a predictor of transplant coronary artery disease in children","volume":"37","author":"Mulla","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB39|cit39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.healun.2003.10.013","article-title":"Pravastatin therapy is associated with reduction in coronary allograft vasculopathy in pediatric heart transplantation","volume":"24","author":"Mahle","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB40|cit40","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.healun.2006.03.022","article-title":"Surveillance for transplant coronary artery disease in infant, child and adolescent heart transplant recipients: an intravascular ultrasound study","volume":"25","author":"Nicolas","year":"2006","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB41|cit41","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/01.TP.0000155246.52249.AC","article-title":"Development of posttransplant antidonor HLA antibodies is associated with acute humoral rejection and early graft dysfunction","volume":"79","author":"Zhang","year":"2005","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB42|cit42","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.healun.2003.07.027","article-title":"Clinical impact of cytokine gene polymorphisms in heart and lung transplantation","volume":"23","author":"Holweg","year":"2004","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB43|cit43","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0065-2776(08)60623-9","article-title":"Leukocyte migration and adhesion","volume":"58","author":"Imhof","year":"1995","journal-title":"Adv Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB44|cit44","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0198-8859(01)00208-7","article-title":"Identification of ICAM-1 polymorphism that is associated with protection from transplant associated vasculopathy after cardiac transplantation","volume":"62","author":"Borozdenkova","year":"2001","journal-title":"Hum Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB45|cit45","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1161\/01.CIR.92.4.748","article-title":"Cardiac release of cytokines and inflammatory responses in acute myocardial infarction","volume":"92","author":"Neumann","year":"1995","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB46|cit46","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0165-2478(89)90056-4","article-title":"Interleukin 6 primes human neutrophil and monocyte oxidative burst response","volume":"21","author":"Kharazmi","year":"1989","journal-title":"Immunol Lett"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB47|cit47","first-page":"1248","article-title":"L-arginine prevents heart transplant arteriosclerosis by modulating the vascular cell proliferative response to insulin-like growth factor-I and interleukin-6","volume":"15","author":"Lou","year":"1996","journal-title":"J Heart Lung Transplant"},{"issue":"12","key":"10.1111\/j.1747-0803.2011.00601.x-BIB48|cit48","doi-asserted-by":"crossref","first-page":"3773","DOI":"10.1002\/j.1460-2075.1989.tb08554.x","article-title":"Dual control of C-reactive protein gene expression by interleukin-1 and interleukin-6","volume":"8","author":"Ganter","year":"1989","journal-title":"EMBO J"},{"issue":"5","key":"10.1111\/j.1747-0803.2011.00601.x-BIB49|cit49","first-page":"L1057","article-title":"Endothelial permeability and IL-6 production during hypoxia: role of ROS in signal transduction","volume":"277","author":"Ali","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB50|cit50","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1172\/JCI2629","article-title":"The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis","volume":"102","author":"Fishman","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB51|cit51","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.healun.2004.03.016","article-title":"Interleukin-6 polymorphism: a genetic risk factor for cardiac transplant related coronary vasculopathy?","volume":"24","author":"Densem","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB52|cit52","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/00007890-200105270-00018","article-title":"The transforming growth factor-beta1 codon 10 gene polymorphism and accelerated graft vascular disease after clinical heart transplantation","volume":"71","author":"Holweg","year":"2001","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB53|cit53","first-page":"363","article-title":"Transforming growth factor-beta: a general review","volume":"7","author":"Lawrence","year":"1996","journal-title":"Eur Cytokine Netw"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB54|cit54","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.trim.2004.06.005","article-title":"Donor and recipient-transforming growth factor-beta 1 polymorphism and cardiac transplant-related coronary artery disease","volume":"13","author":"Densem","year":"2004","journal-title":"Transpl Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB55|cit55","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S1053-2498(01)00358-8","article-title":"Influence of tumor necrosis factor-alpha gene-308 polymorphism on the development of coronary vasculopathy after cardiac transplantation","volume":"20","author":"Densem","year":"2001","journal-title":"J Heart Lung Transplant"},{"issue":"6","key":"10.1111\/j.1747-0803.2011.00601.x-BIB56|cit56","first-page":"H2535","article-title":"Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation","volume":"266","author":"Wang","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB57|cit57","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0002-9149(97)00972-7","article-title":"Levels of circulating adhesion molecules in congestive heart failure and after heart transplantation","volume":"81","author":"Andreassen","year":"1998","journal-title":"Am J Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB58|cit58","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.healun.2004.02.019","article-title":"Tumor necrosis factor gene polymorphism and cardiac allograft vasculopathy","volume":"24","author":"Ternstrom","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB59|cit59","first-page":"935","article-title":"The role of fibrinolytic genes and proteins in the development of allograft vascular disease","volume":"30","author":"Benza","year":"2011","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB60|cit60","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1161\/01.CIR.98.21.2248","article-title":"Gene polymorphisms for plasminogen activator inhibitor-1\/tissue plasminogen activator and development of allograft coronary artery disease","volume":"98","author":"Benza","year":"1998","journal-title":"Circulation"},{"issue":"15","key":"10.1111\/j.1747-0803.2011.00601.x-BIB61|cit61","doi-asserted-by":"crossref","first-page":"6972","DOI":"10.1016\/S0021-9258(19)62711-0","article-title":"The human tissue plasminogen activator gene","volume":"261","author":"Degen","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB62|cit62","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1161\/01.ATV.11.1.183","article-title":"Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity","volume":"11","author":"Dawson","year":"1991","journal-title":"Arterioscler Thromb"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB63|cit63","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1080\/07853890310025243","article-title":"Role of angiogenic growth factors in transplant coronary artery disease","volume":"36","author":"Lemstrom","year":"2004","journal-title":"Ann Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB64|cit64","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.healun.2006.02.006","article-title":"Genetic polymorphism in platelet-derived growth factor and vascular endothelial growth factor are significantly associated with cardiac allograft vasculopathy","volume":"25","author":"Tambur","year":"2006","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB65|cit65","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1681\/ASN.V131260","article-title":"Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection","volume":"13","author":"Shahbazi","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB66|cit66","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/01.TP.0000147199.60464.F9","article-title":"Combined vascular endothelial growth factor and platelet-derived growth factor inhibition in rat cardiac allografts: beneficial effects on inflammation and smooth muscle cell proliferation","volume":"79","author":"Nykanen","year":"2005","journal-title":"Transplantation"},{"issue":"2-3","key":"10.1111\/j.1747-0803.2011.00601.x-BIB67|cit67","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ijcard.2003.05.027","article-title":"The renin-angiotensin hypothesis for the pathogenesis of cardiac allograft vasculopathy","volume":"95","author":"Yousufuddin","year":"2004","journal-title":"Int J Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB68|cit68","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.healun.2004.06.005","article-title":"The effect of combined Angiotensin-converting enzyme inhibition and calcium antagonism on allograft coronary vasculopathy validated by intravascular ultrasound","volume":"24","author":"Erinc","year":"2005","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB69|cit69","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1432-2277.2003.tb00219.x","article-title":"Two good reasons for an angiotensin-II type 1 receptor blockade with losartan after cardiac transplantation: reduction of incidence and severity of transplant vasculopathy","volume":"16","author":"Richter","year":"2003","journal-title":"Transpl Int"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB70|cit70","first-page":"197","article-title":"Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels","volume":"51","author":"Tiret","year":"1992","journal-title":"Am J Hum Genet"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB71|cit71","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1136\/hrt.74.6.584","article-title":"Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction","volume":"74","author":"Arbustini","year":"1995","journal-title":"Br Heart J"},{"issue":"6396","key":"10.1111\/j.1747-0803.2011.00601.x-BIB72|cit72","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/359641a0","article-title":"Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction","volume":"359","author":"Cambien","year":"1992","journal-title":"Nature"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB73|cit73","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/S1053-2498(00)00213-8","article-title":"ACE-gene polymorphism is associated with the development of allograft vascular disease in heart transplant recipients","volume":"19","author":"Pethig","year":"2000","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB74|cit74","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1053\/euhj.1997.0587","article-title":"Donor ACE gene polymorphism: a genetic risk factor for accelerated coronary sclerosis following cardiac transplantation","volume":"19","author":"Cunningham","year":"1998","journal-title":"Eur Heart J"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB75|cit75","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1056\/NEJM199509073331003","article-title":"Effect of pravastatin on outcomes after cardiac transplantation","volume":"333","author":"Kobashigawa","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB76|cit76","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S1053-2498(03)00193-1","article-title":"Hypercholesterolemia is common after pediatric heart transplantation: initial experience with pravastatin","volume":"23","author":"Seipelt","year":"2004","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB77|cit77","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.healun.2006.06.003","article-title":"Hyperlipidemia in children after heart transplantation","volume":"25","author":"Singh","year":"2006","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB78|cit78","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/0002-9149(94)90856-7","article-title":"Cardiac allograft vasculopathy assessed by intravascular ultrasonography and nonimmunologic risk factors","volume":"74","author":"Escobar","year":"1994","journal-title":"Am J Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB79|cit79","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1056\/NEJM199108083250601","article-title":"A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction","volume":"325","author":"Stampfer","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB80|cit80","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1399-3046.2007.00690.x","article-title":"Low HDL-C predicts the onset of transplant vasculopathy in pediatric cardiac recipients on pravastatin therapy","volume":"11","author":"Hedman","year":"2007","journal-title":"Pediatr Transplant"},{"issue":"6","key":"10.1111\/j.1747-0803.2011.00601.x-BIB81|cit81","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1161\/01.CIR.81.6.2004","article-title":"Hyperhomocyst(e)inemia. A common and easily reversible risk factor for occlusive atherosclerosis","volume":"81","author":"Malinow","year":"1990","journal-title":"Circulation"},{"issue":"5","key":"10.1111\/j.1747-0803.2011.00601.x-BIB82|cit82","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/0735-1097(90)90542-W","article-title":"Plasma homocyst(e)ine levels in men with premature coronary artery disease","volume":"16","author":"Genest","year":"1990","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB83|cit83","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0735-1097(95)00508-0","article-title":"Homocysteine and coronary atherosclerosis","volume":"27","author":"Mayer","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB84|cit84","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S1053-2498(99)00013-3","article-title":"Effect of immunosuppressive therapy, serum creatinine, and time after transplant on plasma total homocysteine in patients following heart transplantation","volume":"18","author":"Cook","year":"1999","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB85|cit85","doi-asserted-by":"crossref","first-page":"S235","DOI":"10.1111\/j.1432-2277.2000.tb02026.x","article-title":"Elevated plasma homocysteine concentrations after pediatric heart transplantations","volume":"13","author":"Parisi","year":"2000","journal-title":"Transpl Int"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB86|cit86","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.healun.2003.09.004","article-title":"Increased plasma homocysteine concentrations accelerate cardiac allograft vasculopathy","volume":"23","author":"Kutschka","year":"2004","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB87|cit87","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1034\/j.1399-0012.2001.150407.x","article-title":"Hyperhomocysteinemia and transplant coronary artery disease in cardiac transplant recipients","volume":"15","author":"Miner","year":"2001","journal-title":"Clin Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB88|cit88","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1056\/NEJM199804093381507","article-title":"Homocysteine and atherothrombosis","volume":"338","author":"Welch","year":"1998","journal-title":"N Engl J Med"},{"issue":"5","key":"10.1111\/j.1747-0803.2011.00601.x-BIB89|cit89","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1161\/01.CIR.95.5.1119","article-title":"Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans","volume":"95","author":"Tawakol","year":"1997","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB90|cit90","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S1053-2498(02)00666-6","article-title":"Treatment of hyperhomocysteinemia in pediatric heart transplant recipients","volume":"22","author":"Parisi","year":"2003","journal-title":"J Heart Lung Transplant"},{"issue":"9","key":"10.1111\/j.1747-0803.2011.00601.x-BIB91|cit91","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1111\/j.1600-6143.2005.01015.x","article-title":"Homocysteine-lowering therapy and early progression of transplant vasculopathy: a prospective, randomized, IVUS-based study","volume":"5","author":"Potena","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB92|cit92","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1097\/TP.0b013e31816b2602","article-title":"Long-term effect of folic acid therapy in heart transplant recipients: follow-up analysis of a randomized study","volume":"85","author":"Potena","year":"2008","journal-title":"Transplantation"},{"issue":"1-2","key":"10.1111\/j.1747-0803.2011.00601.x-BIB93|cit93","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1023\/A:1024759311013","article-title":"The relationship between human cytomegalovirus infection and atherosclerosis development","volume":"249","author":"Chen","year":"2003","journal-title":"Mol Cell Biochem"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB94|cit94","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1001\/jama.1989.03420240075030","article-title":"Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis","volume":"261","author":"Grattan","year":"1989","journal-title":"JAMA"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB95|cit95","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/modpathol.3880032","article-title":"CMV and transplant-related coronary atherosclerosis: an immunohistochemical, in situ hybridization, and polymerase chain reaction in situ study","volume":"13","author":"Sambiase","year":"2000","journal-title":"Mod Pathol"},{"issue":"1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB96|cit96","first-page":"25","article-title":"Role of CMV in transplant coronary artery disease and survival after heart transplantation","volume":"1","author":"Valantine","year":"1999","journal-title":"Transpl Infect Dis"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB97|cit97","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1097\/01.TP.0000090163.48433.48","article-title":"Cytomegalovirus infection status predicts progression of heart-transplant vasculopathy","volume":"76","author":"Fateh-Moghadam","year":"2003","journal-title":"Transplantation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB98|cit98","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1161\/CIRCULATIONAHA.106.627570","article-title":"Positive pretransplantation cytomegalovirus serology is a risk factor for cardiac allograft vasculopathy in children","volume":"115","author":"Hussain","year":"2007","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB99|cit99","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1161\/CIRCULATIONAHA.107.718874","article-title":"Endothelial dysfunction and cytomegalovirus replication in pediatric heart transplantation","volume":"117","author":"Simmonds","year":"2008","journal-title":"Circulation"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB100|cit100","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.healun.2009.07.011","article-title":"Does cytomegalovirus serology impact outcome after pediatric heart transplantation?","volume":"28","author":"Mahle","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB101|cit101","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1056\/NEJM200105173442002","article-title":"Association of viral genome with graft loss in children after cardiac transplantation","volume":"344","author":"Shirali","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB102|cit102","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S1053-2498(00)00419-8","article-title":"Association of viral genome with transplant coronary arteriopathy and graft loss in children following cardiac transplantation","volume":"20","author":"Bowles","year":"2001","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB103|cit103","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.jacc.2010.02.060","article-title":"Viral endomyocardial infection is an independent predictor and potentially treatable risk factor for graft loss and coronary vasculopathy in pediatric cardiac transplant recipients","volume":"56","author":"Moulik","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1111\/j.1747-0803.2011.00601.x-BIB104|cit104","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1111\/j.1600-6143.2009.02801.x","article-title":"Viral infection induces de novo lesions of coronary allograft vasculopathy through a natural killer cell-dependent pathway","volume":"9","author":"Graham","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB105|cit105","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report","volume":"289","author":"Chobanian","year":"2003","journal-title":"JAMA"},{"issue":"9349","key":"10.1111\/j.1747-0803.2011.00601.x-BIB106|cit106","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/S0140-6736(02)11911-8","article-title":"Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies","volume":"360","author":"Lewington","year":"2002","journal-title":"Lancet"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB107|cit107","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/1010-7940(90)90207-G","article-title":"Risk factors for development of accelerated coronary artery disease in cardiac transplant recipients","volume":"4","author":"Radovancevic","year":"1990","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB108|cit108","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1056\/NEJM199301213280303","article-title":"A preliminary study of diltiazem in the prevention of coronary artery disease in heart-transplant recipients","volume":"328","author":"Schroeder","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB109|cit109","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/0002-9149(89)90182-3","article-title":"Frequency of angiographic detection and quantitative assessment of coronary arterial disease one and three years after cardiac transplantation","volume":"63","author":"O'Neill","year":"1989","journal-title":"Am J Cardiol"},{"issue":"9","key":"10.1111\/j.1747-0803.2011.00601.x-BIB110|cit110","first-page":"II69","article-title":"Outcome of cardiac transplantation in children. Survival in a contemporary multi-institutional experience. Pediatric Heart Transplant Study","volume":"94","author":"Shaddy","year":"1996","journal-title":"Circulation"},{"issue":"2S1","key":"10.1111\/j.1747-0803.2011.00601.x-BIB111|cit111","doi-asserted-by":"crossref","first-page":"S124","DOI":"10.1016\/j.healun.2008.11.174","article-title":"The presence of cardiac allograft vasculopathy in infant and pediatric heart transplant recipients: a 10-year intravascular ultrasound study","volume":"28","author":"Kuhn","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB112|cit112","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.healun.2009.11.108","article-title":"Impact of B-Cell memory on development of donor-specific tolerance in ABO-incompatible heart transplantation in early childhood","volume":"29","author":"Urschel","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB113|cit113","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/S0264-410X(98)00098-X","article-title":"Infant B-cell response to polysaccharide determinants","volume":"16","author":"Rijkers","year":"1998","journal-title":"Vaccine"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB114|cit114","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1056\/NEJM200103153441102","article-title":"ABO-incompatible heart transplantation in infants","volume":"344","author":"West","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB115|cit115","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1600-6143.2009.02934.x","article-title":"Equivalent outcomes for pediatric heart transplantation recipients: ABO-blood group incompatible versus ABO-compatible","volume":"10","author":"Dipchand","year":"2010","journal-title":"Am J Transplant"},{"issue":"3","key":"10.1111\/j.1747-0803.2011.00601.x-BIB116|cit116","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.4049\/jimmunol.176.3.1962","article-title":"Effacing of the T cell compartment by cardiac transplantation in infancy","volume":"176","author":"Ogle","year":"2006","journal-title":"J Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB117|cit117","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1128\/CDLI.12.5.563-565.2005","article-title":"Levels of recent thymic emigrant cells decrease in children undergoing partial thymectomy during cardiac surgery","volume":"12","author":"Madhok","year":"2005","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1111\/j.1747-0803.2011.00601.x-BIB118|cit118","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.healun.2006.09.020","article-title":"Cardiac re-transplantation in pediatrics: a multi-institutional study","volume":"25","author":"Chin","year":"2006","journal-title":"J Heart Lung Transplant"}],"container-title":["Congenital Heart Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1747-0803.2011.00601.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T19:00:31Z","timestamp":1640026831000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1111\/j.1747-0803.2011.00601.x"}},"subtitle":["Pediatric CAV Pathogenesis"],"short-title":[],"issued":{"date-parts":[[2011,12,18]]},"references-count":118,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,7]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1747-0803.2011.00601.x","relation":{},"ISSN":["1747-079X"],"issn-type":[{"value":"1747-079X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12,18]]}}}