{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:01:56Z","timestamp":1783774916776,"version":"3.55.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T00:00:00Z","timestamp":1357516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Infarctions of the anterior choroidal artery affect multiple anatomical structures, leading to a wide spectrum of neurological deficits with frequent symptom fluctuation or progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To assess etiological mechanisms, frequency, and predicttorsof symptom progression, as well as its impact on prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Anterior choroidal artery infarct patients were prospectively identified via predefined infarct locations with ischemic lesions \u2a7e1\u00b75 cm vertical diameter in cerebral imaging. Definition of neurological progression was \u2a7e2 National Institutes of Health Stroke Scale points in motor function or \u2a7e4 in total National Institutes of Health Stroke Scale. Stroke etiology was determined according to Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. We assessed demographical data, risk factors, and acute phase parameters in order to find predictors of neurological progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty patients fulfilled the inclusion criteria. Eighteen patients (60%) had neurological progression during days 1\u20133. Despite similar stroke severity at admission (median National Institutes of Health Stroke Scale in progressive infarcts 4\u00b75 versus 4; P = 0\u00b772), patients with progression had more severe deficits at day 3 (median National Institutes of Health Stroke Scale 9 vs. 3\u00b75; P = 0\u00b704) and worse three-month outcome. Only 31% of patients with progression scored &lt;2 in the modified Rankin Scale compared with 89% without progression ( P = 0\u00b701) after three-months. No statistically significant differences regarding possible predictors of progression were found. Magnetic resonance imaging findings and etiological assessment suggest overlapping mechanisms of small and large vessel disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Neurological deterioration is frequent in anterior choroidal artery infarcts and is associated with worse outcome. While mechanisms of small and large vessel disease seem to overlap in anterior choroidal artery infarction, we were not able to identify predictors of neurological progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1747-4949.2012.00953.x","type":"journal-article","created":{"date-parts":[[2013,1,7]],"date-time":"2013-01-07T10:07:23Z","timestamp":1357553243000},"page":"134-137","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["The Progressive Course of Neurological Symptoms in Anterior Choroidal Artery Infarcts"],"prefix":"10.1177","volume":"10","author":[{"given":"Sabine","family":"Derflinger","sequence":"first","affiliation":[{"name":"Department of Neurology, Klinikum Rechts der Isar, Technical University of Munich, M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen B.","family":"Fiebach","sequence":"additional","affiliation":[{"name":"Center for Stroke Research, Campus Benjamin Franklin, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"B\u00f6ttger","sequence":"additional","affiliation":[{"name":"Department of Neurology, St\u00e4dtisches Klinikum M\u00fcnchen GmbH, Klinikum Harlaching, M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman L.","family":"Haberl","sequence":"additional","affiliation":[{"name":"Department of Neurology, St\u00e4dtisches Klinikum M\u00fcnchen GmbH, Klinikum Harlaching, M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich J.","family":"Audebert","sequence":"additional","affiliation":[{"name":"Center for Stroke Research, Campus Benjamin Franklin, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,1,7]]},"reference":[{"key":"bibr1-j.1747-4949.2012.00953.x","first-page":"269","volume":"64","author":"Uz A","year":"2005","journal-title":"Folia Morphol (Warsz)"},{"key":"bibr2-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1986.00520070039015"},{"key":"bibr3-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00980.x"},{"key":"bibr4-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.4.825"},{"key":"bibr5-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0855"},{"key":"bibr6-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.32.8.871"},{"key":"bibr7-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000016326.78014.FE"},{"key":"bibr8-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.4.481"},{"key":"bibr9-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.02.323"},{"key":"bibr10-j.1747-4949.2012.00953.x","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.4.837"}],"container-title":["International Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1747-4949.2012.00953.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/j.1747-4949.2012.00953.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1111\/j.1747-4949.2012.00953.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1111\/j.1747-4949.2012.00953.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:46:15Z","timestamp":1777610775000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1111\/j.1747-4949.2012.00953.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,7]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/j.1747-4949.2012.00953.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1747-4949.2012.00953.x","relation":{},"ISSN":["1747-4930","1747-4949"],"issn-type":[{"value":"1747-4930","type":"print"},{"value":"1747-4949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,7]]}}}