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The case was complicated by the presence of markedly elevated serum liver enzyme activities, hyperbilirubinaemia, coagulopathy and ultrasonographic evidence of gall bladder choleliths and extrahepatic bile duct obstruction. The choleliths consisted of 100 per cent bilirubin, likely because of chronic haemolysis and haeme degradation. In conclusion, haemosiderosis and bilirubin cholelithiasis can be a consequence of chronic haemolysis in pyruvate kinase\u2010deficient cats, as seen in human beings with a variety of chronic haemolytic disorders.<\/jats:bold> <\/jats:p>","DOI":"10.1111\/j.1748-5827.2008.00568.x","type":"journal-article","created":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T10:30:21Z","timestamp":1217932221000},"page":"479-482","source":"Crossref","is-referenced-by-count":20,"title":["Bilirubin cholelithiasis and haemosiderosis in an anaemic pyruvate kinase\u2010deficient Somali cat"],"prefix":"10.1111","volume":"49","author":[{"given":"C.","family":"Van Geffen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Savary\u2010Bataille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Chiers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Giger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Daminet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,9,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00383-002-0804-5","article-title":"Should cholecystectomy be performed concomitantly with splenectomy in children with sickle\u2010cell disease?","volume":"19","author":"Al\u2010Salem A. 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