{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:30:55Z","timestamp":1790742655202,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T00:00:00Z","timestamp":1334016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p><jats:bold>O<jats:sc>bjective<\/jats:sc>: To determine the effect of signalment on the incidence and presentation of patients suffering from cranial cruciate ligament disease.<\/jats:bold><\/jats:p><jats:p><jats:bold>M<jats:sc>ethods<\/jats:sc>: Data relating to 426 dogs (44 breeds) that met specific selection criteria were obtained from the hospital archive (2002 to 2008). Cases were followed up for 2 years.<\/jats:bold><\/jats:p><jats:p><jats:bold>R<jats:sc>esults<\/jats:sc>: The breeds most commonly presented with cranial cruciate ligament disease were Labrador retriever (16%), Rottweiler (15%), golden retriever (12%) and boxer (9%). Rottweilers were significantly more likely (69%; P=0\u00b705) to develop and present with (50%; P=0\u00b703) bilateral cranial cruciate ligament disease. Rottweilers presenting with cranial cruciate ligament disease were significantly younger (median 977 days; P&lt;0\u00b70001) than other breeds; golden retrievers being significantly older at presentation (median 1994 days; P=0\u00b7004). Neither sex nor neutered status significantly affected the incidence of developing (P=0\u00b777 and P=0\u00b730, respectively) or presenting with (P=0\u00b762 and P=0\u00b735, respectively) bilateral cranial cruciate ligament disease. Entire dogs were significantly younger than neutered dogs at presentation (P=0\u00b70004). Entire female dogs presented significantly younger than neutered females (P=0\u00b70002), entire males (P=0\u00b701) and neutered males (P=0\u00b70001).<\/jats:bold><\/jats:p><jats:p><jats:bold>C<jats:sc>linical<\/jats:sc>S<jats:sc>ignificance<\/jats:sc>: Breed affects the incidence of developing and presenting with bilateral cranial cruciate ligament disease. Breed and sex both affect the age that patients present with cranial cruciate ligament disease.<\/jats:bold><\/jats:p>","DOI":"10.1111\/j.1748-5827.2011.01202.x","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T12:45:26Z","timestamp":1334061926000},"page":"273-277","source":"Crossref","is-referenced-by-count":32,"title":["Effect of signalment on the presentation of canine patients suffering from cranial cruciate ligament disease"],"prefix":"10.1111","volume":"53","author":[{"given":"J. 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