{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:42:37Z","timestamp":1789785757822,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,3,20]],"date-time":"2006-03-20T00:00:00Z","timestamp":1142812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> A preliminary study to investigate the intra\u2010observer and inter\u2010observer variability of measurements of vestibular schwannoma volume using an area\u2010tracing and linear dimension measurement method.<\/jats:p><jats:p><jats:bold>Design:\u2002<\/jats:bold> Prospective blinded measurements by two observers (one a consultant and one a sub\u2010specialty trainee in neuroradiology).<\/jats:p><jats:p><jats:bold>Setting:\u2002<\/jats:bold> Ambulatory patients with known vestibular schwannoma attending a tertiary referral centre.<\/jats:p><jats:p><jats:bold>Participants:\u2002<\/jats:bold> Twenty\u2010three patients with 26 vestibular schwannomas aged 29\u201380\u2003years old.<\/jats:p><jats:p><jats:bold>Main outcome measure:\u2002<\/jats:bold> Quantification of the variability in measured volume due to intra\u2010 and inter\u2010observer measurement differences, expressed as reliability coefficients within which 95% of repeated measurements are calculated to lie from each other in relative percentage terms.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> For the linear measurement method, intraobserver variability was calculated to have a reliability coefficient of 65% and for interobserver variability this was 155%. For the area tracing method, the corresponding coefficients were 26% for intraobserver variability and 44% for interobserver variability.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Volume measurements in vestibular schwannoma are variable even when the measurements are made by the same observer on identical images. The area tracing method, commonly regarded as the gold standard, is less variable than a linear method but still introduces more variability than commonly realized (for 95% of patients, repeated measurements by the same observer lie within around 25% of each other). Manual area tracing is not widely used in practice because it is time consuming and reliable automated methods are eagerly awaited.<\/jats:p>","DOI":"10.1111\/j.1749-4486.2006.01161.x","type":"journal-article","created":{"date-parts":[[2006,3,20]],"date-time":"2006-03-20T13:27:56Z","timestamp":1142861276000},"page":"123-129","source":"Crossref","is-referenced-by-count":34,"title":["Reproducibility of volume measurements of vestibular schwannomas \u2013 a preliminary study"],"prefix":"10.1111","volume":"31","author":[{"given":"J.J.","family":"Cross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Baguley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.M.","family":"Antoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.A.","family":"Moffat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.T.","family":"Prevost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,3,20]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199310000-00003"},{"key":"e_1_2_7_3_2","first-page":"244","article-title":"The Growth of Acoustic Neuromas in volumetric radiologic assessment","volume":"20","author":"Niemczyk K.","year":"1999","journal-title":"Am. 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