{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:52:39Z","timestamp":1792057959109,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,10,2]],"date-time":"2006-10-02T00:00:00Z","timestamp":1159747200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p><jats:bold>Objectives:<\/jats:bold> This study summarises the results of a National Audit of sino\u2010nasal surgery carried out in England and Wales. It describes patient and operative characteristics as well as patient outcomes up to 36\u2003months after surgery.<\/jats:p><jats:p><jats:bold>Design:<\/jats:bold> Prospective cohort study.<\/jats:p><jats:p><jats:bold>Setting:<\/jats:bold> NHS hospitals in England and Wales.<\/jats:p><jats:p><jats:bold>Participants:<\/jats:bold> Consecutive patients undergoing surgery for nasal polyposis and\/or chronic rhinosinusitis.<\/jats:p><jats:p><jats:bold>Main outcome measure:<\/jats:bold> The total score derived from a 22\u2010item version of the Sino\u2010Nasal Outcome Test (SNOT\u201022). Lower scores represent better health\u2010related quality of life.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> A total of 3128 consecutive patients at 87 NHS hospitals were enrolled. There is a large improvement in SNOT\u201022 scores from the pre\u2010operative period (mean\u2003=\u200342.0) to 3\u2003months after surgery (mean\u2003=\u200325.5). The scores for patients undergoing nasal polypectomy improved from 41.0 before surgery to 23.1 at 3\u2003months after surgery, while the scores for patients undergoing surgery for chronic rhinosinusitis alone improved from 44.2 to 31.2. The SNOT\u201022 scores reported at 12 and 36\u2003months after surgery were similar to those reported at 3\u2003months. Excessive bleeding occurred in 5% of patients during the operation and in 1% of patients after the operation. Intra\u2010orbital complications were reported in 0.2%. Of those patients undergoing primary surgery for bilateral grade I or II polyposis, 18% had not received a pre\u2010operative course of steroid treatment. At the 36\u2010month follow\u2010up, 11.4% of patients had undergone revision surgery.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The audit confirms that sino\u2010nasal surgery is generally safe and effective. There is some evidence that patient selection for surgery could be improved.<\/jats:p>","DOI":"10.1111\/j.1749-4486.2006.01275.x","type":"journal-article","created":{"date-parts":[[2006,10,2]],"date-time":"2006-10-02T08:45:29Z","timestamp":1159778729000},"page":"390-398","source":"Crossref","is-referenced-by-count":173,"title":["The national comparative audit of surgery for nasal polyposis and chronic rhinosinusitis"],"prefix":"10.1111","volume":"31","author":[{"given":"C.","family":"Hopkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Browne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Slack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Lund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Topham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Copley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Van Der Meulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,2]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Delivering the NHS Plan","author":"Department of Health.","year":"2002"},{"key":"e_1_2_6_3_2","volume-title":"Good Medical Practice","author":"General Medical Council.","year":"2001"},{"key":"e_1_2_6_4_2","volume-title":"Report of the Public Inquiry into Children's Heart Surgery at the Bristol Royal Infirmary 1984\u20131995","author":"Department of Health.","year":"2001"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480252814199"},{"key":"e_1_2_6_6_2","volume-title":"Hospital Episode Statistics: Total Operations 2001 to 2002","author":"Department of Health.","year":"2002"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02439732"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.121022"},{"key":"e_1_2_6_9_2","first-page":"111","article-title":"New classification of physical status","volume":"24","author":"American Society of Anesthesiologists","year":"1963","journal-title":"Anesthesiology"},{"key":"e_1_2_6_10_2","first-page":"183","article-title":"Staging in rhinosinusitis","volume":"107","author":"Lund V.J.","year":"1993","journal-title":"Rhinology"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-198903001-00015"},{"key":"e_1_2_6_12_2","first-page":"2","article-title":"Functional endoscopic sinus surgery: 5\u2003year follow up and results of a prospective, randomised, stratified, double\u2010blind, placebo controlled study of postoperative fluticasone propionate aqueous nasal spray","volume":"43","author":"Rowe\u2010Jones J.M.","year":"2005","journal-title":"Rhinology"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1997.00888.x"},{"key":"e_1_2_6_14_2","volume-title":"Hospital Episode Statistics: Total Operations 2000 to 2001","author":"Department of Health.","year":"2002"},{"key":"e_1_2_6_15_2","volume-title":"National Joint Registry for England and Wales. 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