{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:49:39Z","timestamp":1772160579636,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,10,28]],"date-time":"2011-10-28T00:00:00Z","timestamp":1319760000000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Otolaryngology"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>\n                    <jats:italic>Clin. Otolaryngol.<\/jats:italic>\n                    2011,\n                    <jats:bold>36<\/jats:bold>\n                    , 475\u2013481\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objectives:\u2002<\/jats:bold>\n                    To assess a cohort of patients who underwent adenotonsillectomy for obstructive sleep apnoea, 4\u2003years after surgery for evidence of continued and long\u2010term improvement in quality of life. We also sought to compare our results to Child Health Questionnaire scores obtained from our previous study. We also compared our data with a healthy UK children population from normative data available.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:\u2002<\/jats:bold>\n                    Longitudinal study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Settings:\u2002<\/jats:bold>\n                    University Hospital Tertiary Referral Centre.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Participants:\u2002<\/jats:bold>\n                    A 4\u2010year follow\u2010up study of 37 children who underwent adenotonsillectomy for obstructive sleep apnoea confirmed on polysomnography. There were 19 boys and 18 girls from our initial cohort. The primary caregiver completed the validated Child Health Questionnaire Parental Form version\u201028, 4\u2003years after initial surgery. Our control group consist of 221 healthy children aged 6\u201318 that were included as \u2018normal\u2019 controls in a study looking at children with juvenile arthritis. The children were defined as healthy by a physician and\/or after declaration by the parent.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Main outcome measure:\u2002<\/jats:bold>\n                    Child Health Questionnaire Parental Form version\u201028 scores.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    A total of 33 patients (89%) from our initial cohort were contacted. The mean age was 10.6 (median, 11; range, 5\u201316). When compared with results obtained 3\u2003months postoperatively, the mean scores were higher in five domains and were statistically significant in three subscales (Role Limitations\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.00001; Bodily Pain\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.002; and Global Health\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.02). There was a significant deterioration in Behaviour subscale (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.0007) in spite of surgery. Compared with controls, 4\u2010year follow\u2010up scores were higher in five domains with the Global Health domain (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.0004) being statistically significant. When the 4\u2010year follow\u2010up scores were compared with preoperative values, these were higher in all 13 domains with statistically significant improvements in nine domains, indicating that improvements had persisted 4\u2003years after surgery. At 4\u2003years, however, the means scores in many domains remain lower when compared with controls.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:\u2002<\/jats:bold>\n                    Quality\u2010of\u2010life data are an important measure when deciding on a specific clinical intervention. In the short term, quality\u2010of\u2010life measures have been shown to improve after adenotonsillectomy for obstructive sleep apnoea. Our study demonstrates that the benefits of surgery are still persistent and the children continue to improve in the long term.\n                  <\/jats:p>","DOI":"10.1111\/j.1749-4486.2011.02383.x","type":"journal-article","created":{"date-parts":[[2011,8,20]],"date-time":"2011-08-20T10:16:07Z","timestamp":1313835367000},"page":"475-481","source":"Crossref","is-referenced-by-count":14,"title":["Long\u2010term quality\u2010of\u2010life outcomes in children undergoing adenotonsillectomy for obstructive sleep apnoea: a longitudinal study"],"prefix":"10.1111","volume":"36","author":[{"given":"P.S.","family":"Randhawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Cetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Chilvers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Georgalas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.A.","family":"Narula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,10,28]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-135MG"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1918"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007343"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.105254"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.130.2.190"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.11.003"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/26.8.999"},{"key":"e_1_2_8_9_2","first-page":"457","article-title":"Diagnosis and treatment of sleep apnea in adolescents","volume":"21","author":"Burg C.J.","year":"2010","journal-title":"Adolesc. 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