{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:06:42Z","timestamp":1791266802189,"version":"4.1.0"},"reference-count":110,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2011,5,20]],"date-time":"2011-05-20T00:00:00Z","timestamp":1305849600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>The University of Geneva brain collection was founded at the beginning of the 20th century. Today, it consists of 10,154 formaldehyde\u2010 or buffered formaldehyde\u2013fixed brains obtained from the autopsies of the Department of Psychiatry and, since 1971, from the Department of Geriatrics. More than 100,000 paraffin\u2010embedded blocks and 200,000 histological slides have also been collected since 1901. From the time of its creation, this collection has served as an important resource for pathological studies and clinicopathological correlations, primarily in the field of dementing illnesses and brain aging research. These materials have permitted a number of original neuropathological observations, such as the classification of Pick's disease by Constantinidis, or the description of dyshoric angiopathy and laminar sclerosis by Morel. The large number of cases, including some very rare conditions, provides a unique resource and an opportunity for worldwide collaborations.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2011.06008.x","type":"journal-article","created":{"date-parts":[[2011,5,20]],"date-time":"2011-05-20T21:52:35Z","timestamp":1305928355000},"source":"Crossref","is-referenced-by-count":17,"title":["The Geneva brain collection"],"prefix":"10.1111","volume":"1225","author":[{"given":"Enik\u00f6","family":"K\u00f6vari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick R.","family":"Hof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin","family":"Bouras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1007\/BF01949287","article-title":"De la d\u00e9viation conjugu\u00e9e des yeux et de la rotation de la t\u00eate dans certains cas d\u2019h\u00e9mipl\u00e9gie","volume":"70","author":"Pr\u00e9vost J.l.","year":"1877","journal-title":"Virchow Arch."},{"key":"e_1_2_6_3_2","article-title":"Erythropsie dans la paralysie g\u00e9n\u00e9rale","volume":"273","author":"Ladame P.L.","year":"1889","journal-title":"Congr\u00e8s Int. M\u00e9d. Ment. Paris"},{"key":"e_1_2_6_4_2","article-title":"Alcoolisme et paralysie g\u00e9n\u00e9rale","volume":"144","author":"Ladame P.L.","year":"1891","journal-title":"Congr\u00e8s Int. M\u00e9d. Ment. Lyon"},{"key":"e_1_2_6_5_2","first-page":"40","article-title":"Un cas d\u2019astasie\u2010abasie sous forme d\u2019attaques","volume":"19","author":"Ladame P.L.","year":"1890","journal-title":"Arch. Neurol."},{"key":"e_1_2_6_6_2","article-title":"Les sympt\u00f4mes psychiques de la chor\u00e9e d\u2019Huntington","volume":"721","author":"Ladame P.L.","year":"1899","journal-title":"Rev. M\u00e9d. Suisse Romande"},{"key":"e_1_2_6_7_2","volume-title":"Les Services Psychiatriques de Gen\u00e8ve","year":"1976"},{"key":"e_1_2_6_8_2","first-page":"13","article-title":"La question d\u2019aphasie motrice sous\u2010corticale","volume":"10","author":"Ladame P.L.","year":"1902","journal-title":"Rev. Neurol."},{"key":"e_1_2_6_9_2","first-page":"73","article-title":"Aphasie motrice sous\u2010corticale","volume":"1","author":"Ladame P.L.","year":"1902","journal-title":"Rev. M\u00e9d. Suisse Romande."},{"key":"e_1_2_6_10_2","first-page":"305","article-title":"H\u00e9mianesth\u00e9sie bilat\u00e9rale d\u2019origine c\u00e9r\u00e9brale","volume":"1","author":"Long E.","year":"1921","journal-title":"Rev. Neurol."},{"key":"e_1_2_6_11_2","first-page":"113","article-title":"Un cas d\u2019h\u00e9mipl\u00e9gie de cause c\u00e9r\u00e9brale avec h\u00e9mianesth\u00e9sie persitante","volume":"1","author":"Long E.","year":"1904","journal-title":"Rev. Neurol."},{"key":"e_1_2_6_12_2","first-page":"1","article-title":"De quelques alt\u00e9rations du tissu c\u00e9r\u00e9bral dues \u00e0 la pr\u00e9sence de tumeurs","volume":"2","author":"Weber R.","year":"1905","journal-title":"Nouv. Iconogr. Salp\u00eatri\u00e8re."},{"key":"e_1_2_6_13_2","first-page":"1","article-title":"De quelques alt\u00e9rations du tissu c\u00e9r\u00e9bral dues \u00e0 la pr\u00e9sence de tumeurs","volume":"5","author":"Weber R.","year":"1908","journal-title":"Nouv. Iconogr. Salp\u00eatri\u00e8re."},{"key":"e_1_2_6_14_2","first-page":"8","article-title":"De quelques alt\u00e9rations du tissu c\u00e9r\u00e9bral dues \u00e0 la pr\u00e9sence de tumeurs","volume":"4","author":"Weber R.","year":"1907","journal-title":"Nouv. Iconogr. Salp\u00eatri\u00e8re."},{"key":"e_1_2_6_15_2","first-page":"1","article-title":"De quelques alt\u00e9rations du tissu c\u00e9r\u00e9bral dues \u00e0 la pr\u00e9sence de tumeurs","volume":"3","author":"Weber R.","year":"1906","journal-title":"Nouv. Iconogr. Salp\u00eatri\u00e8re."},{"key":"e_1_2_6_16_2","first-page":"137","article-title":"Note sur la d\u00e9g\u00e9n\u00e9rescence secondaire cons\u00e9cutive \u00e0 un foyer de ramollissement de la r\u00e9gion calcarine","volume":"11","author":"Weber R.","year":"1905","journal-title":"Arch. Neurol."},{"key":"e_1_2_6_17_2","first-page":"116","article-title":"L\u2019histologie pathologioque des maladies mentales","volume":"4","author":"Ladame C.","year":"1909","journal-title":"Enc\u00e9phale"},{"key":"e_1_2_6_18_2","first-page":"244","article-title":"A propos de la syphilis c\u00e9r\u00e9brale diffuse","volume":"2","author":"Ladame C.","year":"1907","journal-title":"Enc\u00e9phale"},{"key":"e_1_2_6_19_2","first-page":"373","article-title":"Syphilis c\u00e9r\u00e9brale diffuse","volume":"2","author":"Ladame C.","year":"1907","journal-title":"Enc\u00e9phale"},{"key":"e_1_2_6_20_2","first-page":"265","article-title":"Paralysie g\u00e9n\u00e9rale, syphilis c\u00e9r\u00e9brale diffuse et psychose art\u00e9rioscl\u00e9rotique","volume":"31","author":"Ladame C.","year":"1911","journal-title":"Rev. M\u00e9d. Suisse. Romande."},{"key":"e_1_2_6_21_2","first-page":"13","article-title":"Enc\u00e9phalite sous\u2010corticale chronique","volume":"7","author":"Ladame C.","year":"1912","journal-title":"Enc\u00e9phale"},{"key":"e_1_2_6_22_2","unstructured":"Ladame C.1933.Asile\u2010clinique Psychiatrique Bel\u2010Air Ch\u00eane(Gen\u00e8ve)."},{"key":"e_1_2_6_23_2","first-page":"270","article-title":"L\u2019hyperostose frontale interne avec adipose et troubles c\u00e9r\u00e9braux","volume":"25","author":"Morel F.","year":"1929","journal-title":"Schweiz. Arch. Neurol. Psychiatr."},{"key":"e_1_2_6_24_2","first-page":"280","article-title":"Une forme anatomo\u2010clinique particuli\u00e8re de l\u2019alcoolisme chronique: scl\u00e9rose corticale laminaire alcoolique","volume":"71","author":"Morel F.","year":"1939","journal-title":"Rev. Neurol."},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1159\/000148423"},{"key":"e_1_2_6_26_2","first-page":"174","article-title":"Contribution \u00e0 la connaissance des diff\u00e9rentes alt\u00e9rations c\u00e9r\u00e9brales du grand \u00e2ge","volume":"76","author":"Morel F.","year":"1955","journal-title":"Schweiz. Arch. Neurol. Psychiatr."},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1159\/000139788"},{"key":"e_1_2_6_28_2","first-page":"18","article-title":"Etat granulaire syst\u00e9matis\u00e9 cardiopathique de l\u2019\u00e9corce c\u00e9r\u00e9brale (atrophie granulaire): \u00e9tude anatomo\u2010clinique","volume":"15","author":"Wildi E.","year":"1959","journal-title":"Bull. Schweiz. Akad. Med. Wiss."},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1159\/000125950"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1159\/000114320"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02146939"},{"key":"e_1_2_6_32_2","first-page":"5","article-title":"Diff\u00e9rences dans le comportement du sang humain et du rat \u00e0 l\u2019\u00e9gard de la 3,4\u2010dihydroxy\u2010L\u2010ph\u00e9nylalanine et du 5\u2010hydroxy\u2010L\u2010tryptophane in vitro","volume":"16","author":"Geissbuhler F.","year":"1978","journal-title":"J. Clin. Chem. Biochem."},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)91056-3"},{"key":"e_1_2_6_34_2","first-page":"213","article-title":"An immunohistochemical study of six biologically active peptides in the human brain","volume":"5","author":"Bouras C.","year":"1986","journal-title":"Hum. Neurobiol."},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(87)92959-9"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(84)90146-5"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(86)90409-X"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-199040100-00003"},{"key":"e_1_2_6_39_2","doi-asserted-by":"publisher","DOI":"10.1159\/000125110"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(89)90392-8"},{"key":"e_1_2_6_41_2","first-page":"207","article-title":"Distribution and colocalization of delta sleep\u2010inducing peptide and luteinizing hormone\u2010releasing hormone in the aged human brain: an immunohistochemical study","volume":"3","author":"Vallet P.G.","year":"1990","journal-title":"J. Chem. Neuroanat."},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(88)90790-2"},{"key":"e_1_2_6_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(91)90194-O"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/79690"},{"key":"e_1_2_6_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(91)90055-X"},{"key":"e_1_2_6_46_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/4.2.138"},{"key":"e_1_2_6_47_2","first-page":"348","article-title":"Dementia in the oldest\u2010old: quantitative analysis of 12 cases from a psychiatric hospital","volume":"5","author":"Giannakopoulos P.","year":"1994","journal-title":"Dementia"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00294172"},{"key":"e_1_2_6_49_2","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/BF00334669","article-title":"1993. Quantitative immunohistochemical analysis of the distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of nonagenarians and centenarians","volume":"85","author":"Giannakopoulos P.","journal-title":"Acta Neuropathol."},{"key":"e_1_2_6_50_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000063311.58879.01"},{"key":"e_1_2_6_51_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010051163"},{"key":"e_1_2_6_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)91173-6"},{"key":"e_1_2_6_53_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199003000-00008"},{"key":"e_1_2_6_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_6_55_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.140.6.566"},{"key":"e_1_2_6_56_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.5.689"},{"key":"e_1_2_6_57_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.1.71"},{"key":"e_1_2_6_58_2","doi-asserted-by":"publisher","DOI":"10.1159\/000017263"},{"key":"e_1_2_6_59_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004019900166"},{"key":"e_1_2_6_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2007.03.007"},{"key":"e_1_2_6_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(93)90305-5"},{"key":"e_1_2_6_62_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.jnen.0000203077.53080.2c"},{"key":"e_1_2_6_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00294173"},{"key":"e_1_2_6_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00056-8"},{"key":"e_1_2_6_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00942-9"},{"key":"e_1_2_6_66_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00389496"},{"key":"e_1_2_6_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-5846(95)00103-3"},{"key":"e_1_2_6_68_2","doi-asserted-by":"publisher","DOI":"10.1159\/000197881"},{"key":"e_1_2_6_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2007.00827.x"},{"key":"e_1_2_6_70_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00304630"},{"key":"e_1_2_6_71_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/62.1.55"},{"key":"e_1_2_6_72_2","doi-asserted-by":"publisher","DOI":"10.1515\/REVNEURO.1995.6.2.97"},{"key":"e_1_2_6_73_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540280065020"},{"key":"e_1_2_6_74_2","first-page":"1075","article-title":"The neuropathological changes associated with normal brain aging","volume":"11","author":"Hof P.R.","year":"1996","journal-title":"Histol. Histopathol."},{"key":"e_1_2_6_75_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb00187.x"},{"key":"e_1_2_6_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2005.11.003"},{"key":"e_1_2_6_77_2","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/358531"},{"key":"e_1_2_6_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2005.02.008"},{"key":"e_1_2_6_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2004.12.005"},{"key":"e_1_2_6_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-003-0705-2"},{"key":"e_1_2_6_81_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000110791.51378.4E"},{"key":"e_1_2_6_82_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000166052.89772.b5"},{"key":"e_1_2_6_83_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm228"},{"key":"e_1_2_6_84_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000257094.10655.9a"},{"key":"e_1_2_6_85_2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s00401-002-0617-6","article-title":"Induction of MC\u20101 immunoreactivity in axons after injection of the Fc fragment of human immunoglobulins in macaque monkeys","volume":"105","author":"Bouras C.","year":"2003","journal-title":"Acta Neuropathol."},{"key":"e_1_2_6_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2004.09.009"},{"key":"e_1_2_6_87_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200301200-00022"},{"key":"e_1_2_6_88_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010100392"},{"key":"e_1_2_6_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2009.08.003"},{"key":"e_1_2_6_90_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2010.01101.x"},{"key":"e_1_2_6_91_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.548545"},{"key":"e_1_2_6_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00189-1"},{"key":"e_1_2_6_93_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019442-200502000-00011"},{"key":"e_1_2_6_94_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00309628"},{"key":"e_1_2_6_95_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010000208"},{"key":"e_1_2_6_96_2","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1999.7263"},{"key":"e_1_2_6_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-9961(02)00011-6"},{"key":"e_1_2_6_98_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-004-0881-8"},{"key":"e_1_2_6_99_2","first-page":"55","article-title":"Asymmetrical cerebral atrophy in Alzheimer's disease","volume":"10","author":"Bugiani O.","year":"1991","journal-title":"Clin. Neuropathol."},{"key":"e_1_2_6_100_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.2.312"},{"key":"e_1_2_6_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(89)90169-9"},{"key":"e_1_2_6_102_2","first-page":"73","article-title":"Frontal arachnoid cyst. A case of bilateral frontal arachnoid cyst without clinical signs","volume":"12","author":"Golaz J.","year":"1993","journal-title":"Clin. Neuropathol."},{"key":"e_1_2_6_103_2","first-page":"491","article-title":"Lowe syndrome: clinical and neuropathological studies of an adult case","volume":"34","author":"Giannakopoulos P.","year":"1990","journal-title":"J. Ment. Defic. Res."},{"key":"e_1_2_6_104_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2006.00719.x"},{"key":"e_1_2_6_105_2","doi-asserted-by":"publisher","DOI":"10.1159\/000112903"},{"key":"e_1_2_6_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(92)90846-Y"},{"key":"e_1_2_6_107_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00296179"},{"key":"e_1_2_6_108_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010050436"},{"key":"e_1_2_6_109_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2009.01039.x"},{"key":"e_1_2_6_110_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00427214"},{"key":"e_1_2_6_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(84)90217-9"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1749-6632.2011.06008.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1749-6632.2011.06008.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T20:13:05Z","timestamp":1695672785000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.2011.06008.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":110,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1111\/j.1749-6632.2011.06008.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1749-6632.2011.06008.x","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}