{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T09:53:05Z","timestamp":1696240385253},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,6,6]],"date-time":"2012-06-06T00:00:00Z","timestamp":1338940800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>Molecular compositions and functions of tight junctions (TJs), that is, continuous, cell\u2013cell\u2010connecting zonulae occludentes serving as barrier structures for the paracellular transport of molecules and particles, have hitherto been determined for simple epithelia and for endothelia. In 2002, special TJ structures with barrier functions were identified in the stratum granulosum of mammalian epidermis. In addition, using biochemical and immunocytochemical methods, various types of TJ\u2010type junctions have also been described that also contain claudins and\/or occludin as well as typical TJ plaque proteins, in cell layers of all stratified squamous epithelia (e.g., various types of epidermis, gingiva, lingual, and other kinds of oral mucosa, pharynx, esophagus, trachea, vagina, and exocervix), including tissues without a lumen, such as the reticulum and Hassall corpuscles of the thymus, and tumors derived from such epithelia, notably squamous cell carcinomas. Biological and pathological aspects of TJ\u2010related structures in such tissues are discussed.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2012.06504.x","type":"journal-article","created":{"date-parts":[[2012,6,6]],"date-time":"2012-06-06T21:27:16Z","timestamp":1339018036000},"page":"152-157","source":"Crossref","is-referenced-by-count":8,"title":["Diverse types of junctions containing tight junction proteins in stratified mammalian epithelia"],"prefix":"10.1111","volume":"1257","author":[{"given":"Werner W.","family":"Franke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich\u2010Frank","family":"Pape","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.17.2.375"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.58.2.390"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7696(08)60940-7"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.38.5.404"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1201\/9781420038538"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.123.6.1777"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.141.7.1539"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200510043"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.143.2.391"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.110.9.1113"},{"key":"e_1_2_7_12_2","first-page":"a002907","article-title":"Molecular basis of the core structure of tight junctions","volume":"1","author":"Furuse M.","year":"2009","journal-title":"Cold Spring Harb. 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