{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:06:36Z","timestamp":1791115596814,"version":"4.1.0"},"reference-count":179,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T00:00:00Z","timestamp":1343088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>In the last 50 years, the average self\u2010reported sleep duration in the United States has decreased by 1.5\u20132 hours in parallel with an increasing prevalence of obesity and diabetes. Epidemiological studies and meta\u2010analyses report a strong relationship between short or disturbed sleep, obesity, and abnormalities in glucose metabolism. This relationship is likely to be bidirectional and causal in nature, but many aspects remain to be elucidated. Sleep and the internal circadian clock influence a host of endocrine parameters. Sleep curtailment in humans alters multiple metabolic pathways, leading to more insulin resistance, possibly decreased energy expenditure, increased appetite, and immunological changes. On the other hand, psychological, endocrine, and anatomical abnormalities in individuals with obesity and\/or diabetes can interfere with sleep duration and quality, thus creating a vicious cycle. In this review, we address mechanisms linking sleep with metabolism, highlight the need for studies conducted in real\u2010life settings, and explore therapeutic interventions to improve sleep, with a potential beneficial effect on obesity and its comorbidities.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2012.06655.x","type":"journal-article","created":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T10:31:43Z","timestamp":1343125903000},"page":"110-134","source":"Crossref","is-referenced-by-count":158,"title":["Interacting epidemics? Sleep curtailment, insulin resistance, and obesity"],"prefix":"10.1111","volume":"1264","author":[{"given":"Eliane A.","family":"Lucassen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina I.","family":"Rother","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Cizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,24]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.39"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.01.003"},{"key":"e_1_2_10_4_2","unstructured":"Centers for Disease Control and Prevention.2011.National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States 2011. Available from:http:\/\/www.cdc.gov\/diabetes\/pubs\/pdf\/ndfs_2011.pdf."},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/27.4.661"},{"key":"e_1_2_10_6_2","first-page":"A146","article-title":"Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased Body Mass Index (BMI)","volume":"27","author":"Taheri S.","year":"2004","journal-title":"Sleep"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.2.205"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.11.2739"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05-0879"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/30.12.1667"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2008.00732.x"},{"key":"e_1_2_10_12_2","volume-title":"Sleep in America Poll","author":"National Sleep Foundation","year":"2005"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2011.07.003"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/31.5.619"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.63"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.4.483"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2008.249"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp230"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj280"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/31.4.517"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/87.2.310"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm298"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.3.289"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.10.1289"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm302"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.2.161"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.32.s3.3.x"},{"key":"e_1_2_10_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.16.1768"},{"key":"e_1_2_10_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.62"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.04.015"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1143"},{"key":"e_1_2_10_32_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1124"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.1.282"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.10.2464"},{"key":"e_1_2_10_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2008.09.016"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1634-x"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2008.12.001"},{"key":"e_1_2_10_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-008-0047-6"},{"key":"e_1_2_10_39_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200909-1423OC"},{"key":"e_1_2_10_40_2","first-page":"2551","article-title":"Sleep problems in the Elderly","volume":"59","author":"Neubauer D.N.","year":"1999","journal-title":"Am. Fam. Physician"},{"key":"e_1_2_10_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.09.006"},{"key":"e_1_2_10_42_2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cmet.2011.01.006","article-title":"Crosstalk between components of circadian and metabolic cycles in mammals","volume":"13","author":"Asher G.","journal-title":"Cell Metab."},{"key":"e_1_2_10_43_2","first-page":"793","article-title":"Chronic sleep deprivation and seasonality: implications for the obesity epidemic","volume":"34","author":"Cizza G.","year":"2011","journal-title":"J. Endocrinol. Invest."},{"key":"e_1_2_10_44_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.197517"},{"key":"e_1_2_10_45_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.38.3.285"},{"key":"e_1_2_10_46_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115396"},{"key":"e_1_2_10_47_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.20.9352"},{"key":"e_1_2_10_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03160568"},{"key":"e_1_2_10_49_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1991.260.4.E651"},{"key":"e_1_2_10_50_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-72-4-854"},{"key":"e_1_2_10_51_2","first-page":"11","article-title":"Slow wave sleep deprivation in relation to plasma growth hormone concentration","volume":"2","author":"Karacan I.","year":"1971","journal-title":"Behav. Neuropsychiatry"},{"key":"e_1_2_10_52_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119587"},{"key":"e_1_2_10_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(69)91300-5"},{"key":"e_1_2_10_54_2","first-page":"613","article-title":"The effect of growth hormone administration on human sleep: a dose\u2010response study","volume":"15","author":"Mendelson W.B.","year":"1980","journal-title":"Biol. Psychiatry"},{"key":"e_1_2_10_55_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.76.6.1428"},{"key":"e_1_2_10_56_2","doi-asserted-by":"crossref","first-page":"E86","DOI":"10.1152\/ajpendo.1990.258.1.E86","article-title":"Effects of a growth hormone pulse on total and forearm substrate fluxes in humans","volume":"258","author":"M\u00f8ller N.","year":"1990","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"e_1_2_10_57_2","unstructured":"Byrne M. J.Sturis J.D.Blackman K.S.Polonsky&E.van Cauter.1992.Decreased glucose tolerance during sleep may be partially mediated by GH. Program of the 74th Annual Meeting of The Endocrine Society San Antonio TX (Abstract 40)."},{"key":"e_1_2_10_58_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00505182"},{"key":"e_1_2_10_59_2","doi-asserted-by":"publisher","DOI":"10.1002\/dmr.5610040105"},{"key":"e_1_2_10_60_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116832"},{"key":"e_1_2_10_61_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1996.271.2.E246"},{"key":"e_1_2_10_62_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00015.2004"},{"key":"e_1_2_10_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2009.06.003"},{"key":"e_1_2_10_64_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-0425"},{"key":"e_1_2_10_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.189"},{"key":"e_1_2_10_66_2","doi-asserted-by":"publisher","DOI":"10.1089\/met.2011.0123"},{"key":"e_1_2_10_67_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm125"},{"key":"e_1_2_10_68_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-006-0969-2"},{"key":"e_1_2_10_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-010-1869-7"},{"key":"e_1_2_10_70_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05314blu"},{"key":"e_1_2_10_71_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199302043280502"},{"key":"e_1_2_10_72_2","doi-asserted-by":"publisher","DOI":"10.1038\/89522"},{"key":"e_1_2_10_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-351X(05)80179-X"},{"key":"e_1_2_10_74_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-60-6-1210"},{"key":"e_1_2_10_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0597-575"},{"key":"e_1_2_10_76_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1109951"},{"key":"e_1_2_10_77_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1978"},{"key":"e_1_2_10_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(01)80035-0"},{"key":"e_1_2_10_79_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00007.2010"},{"key":"e_1_2_10_80_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.9.8002"},{"key":"e_1_2_10_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn1226"},{"key":"e_1_2_10_82_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00460.2007"},{"key":"e_1_2_10_83_2","doi-asserted-by":"crossref","first-page":"4454","DOI":"10.4049\/jimmunol.158.9.4454","article-title":"Effects of sleep and circadian rhythm on human circulating immune cells","volume":"158","author":"Born J.","year":"1997","journal-title":"J. Immul."},{"key":"e_1_2_10_84_2","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2002.33357"},{"key":"e_1_2_10_85_2","doi-asserted-by":"publisher","DOI":"10.1159\/000127219"},{"key":"e_1_2_10_86_2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/clinchem\/47.3.426","article-title":"Absence of diurnal variation of C\u2010reactive protein concentration in healthy human subjects","volume":"47","author":"Meier\u2010Ewert H.K.","year":"2001","journal-title":"Clin. Chem."},{"key":"e_1_2_10_87_2","first-page":"42","article-title":"Variations in high\u2010sensitivity C\u2010reactive protein levels over 24 hours in patients with stable coronary artery disease","volume":"37","author":"Koc M.","year":"2010","journal-title":"Tex. Heart. Inst. J."},{"key":"e_1_2_10_88_2","first-page":"165","article-title":"Metabolic reflection of sleep deprivation","volume":"11","author":"Kuhn E.","year":"1969","journal-title":"Act. Nerv. Super"},{"key":"e_1_2_10_89_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-64-1-157"},{"key":"e_1_2_10_90_2","first-page":"487","article-title":"Effects of sleep deprivation and exercise on glucose tolerance","volume":"64","author":"VanHelder T.","year":"1993","journal-title":"Aviat. Space Environ. Med."},{"key":"e_1_2_10_91_2","first-page":"80","article-title":"Effect of sleep deprivation on insulin sensitivity and cortisol concentration in healthy subjects","volume":"13","author":"Gonz\u00e1les\u2010Ortiz M.","year":"2000","journal-title":"Diabetes Nutr. Metab."},{"key":"e_1_2_10_92_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2869.2000.00225.x"},{"key":"e_1_2_10_93_2","first-page":"307","article-title":"Efficacy and safety of prolonged\u2010release melatonin in insomnia patients with diabetes: a randomized, double\u2010blind, crossover study","volume":"4","author":"Garfinkel D.","year":"2011","journal-title":"Diabetes Metab. Syndr. Obes."},{"key":"e_1_2_10_94_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.112270"},{"key":"e_1_2_10_95_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.2003.01069.x"},{"key":"e_1_2_10_96_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00527.2003"},{"key":"e_1_2_10_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2007.04.003"},{"key":"e_1_2_10_98_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-2788"},{"key":"e_1_2_10_99_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2008.00662.x"},{"key":"e_1_2_10_100_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2010.00844.x"},{"key":"e_1_2_10_101_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.006460"},{"key":"e_1_2_10_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01376-8"},{"key":"e_1_2_10_103_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2000.279.3.R874"},{"key":"e_1_2_10_104_2","first-page":"6S11","article-title":"Impact of sleep debt on physiological rhythms","volume":"159","author":"Spiegel K.","year":"2003","journal-title":"Rev. Neurol."},{"key":"e_1_2_10_105_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-11-200412070-00008"},{"key":"e_1_2_10_106_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-1003"},{"key":"e_1_2_10_107_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031562"},{"key":"e_1_2_10_108_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.16.1756"},{"key":"e_1_2_10_109_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/30.9.1145"},{"key":"e_1_2_10_110_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0483"},{"key":"e_1_2_10_111_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.27984"},{"key":"e_1_2_10_112_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0969"},{"key":"e_1_2_10_113_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004589"},{"key":"e_1_2_10_114_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28523"},{"key":"e_1_2_10_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2010.05.041"},{"key":"e_1_2_10_116_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-2317"},{"key":"e_1_2_10_117_2","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1093\/sleep\/33.8.1115","article-title":"Changes in serum TSH and free T4 during human sleep restriction","volume":"33","author":"Kessler L.","year":"2010","journal-title":"Sleep"},{"key":"e_1_2_10_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2010.01.028"},{"key":"e_1_2_10_119_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-7-201010050-00006"},{"key":"e_1_2_10_120_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.3.371"},{"key":"e_1_2_10_121_2","doi-asserted-by":"publisher","DOI":"10.1177\/1099800410366301"},{"key":"e_1_2_10_122_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2010.08.006"},{"key":"e_1_2_10_123_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.013904"},{"key":"e_1_2_10_124_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0706446105"},{"key":"e_1_2_10_125_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0791"},{"key":"e_1_2_10_126_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.017632"},{"key":"e_1_2_10_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(95)90312-7"},{"key":"e_1_2_10_128_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/18.7.581"},{"key":"e_1_2_10_129_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2858"},{"key":"e_1_2_10_130_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00558.2001"},{"key":"e_1_2_10_131_2","doi-asserted-by":"publisher","DOI":"10.1159\/000127150"},{"key":"e_1_2_10_132_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109718"},{"key":"e_1_2_10_133_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.45.10.1373"},{"key":"e_1_2_10_134_2","article-title":"Beyond fast food and slow motion: weighty contributors to the obesity epidemic","author":"Cizza G.","year":"2012","journal-title":"J. Endocrinol. Invest.35: 236\u2013242."},{"key":"e_1_2_10_135_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.319"},{"key":"e_1_2_10_136_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017435"},{"key":"e_1_2_10_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2008.10.016"},{"key":"e_1_2_10_138_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.2.147"},{"key":"e_1_2_10_139_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.248"},{"key":"e_1_2_10_140_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2010.00870.x"},{"key":"e_1_2_10_141_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-05-01656.2001"},{"key":"e_1_2_10_142_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117495"},{"key":"e_1_2_10_143_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.suppl_2.S114"},{"key":"e_1_2_10_144_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp078030"},{"key":"e_1_2_10_145_2","doi-asserted-by":"publisher","DOI":"10.1080\/13813450802181047"},{"key":"e_1_2_10_146_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.05.035"},{"key":"e_1_2_10_147_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1119377"},{"key":"e_1_2_10_148_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2011.06.027"},{"key":"e_1_2_10_149_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2011.11.009"},{"key":"e_1_2_10_150_2","first-page":"61","article-title":"Effect of surgical weight loss on sleep architecture in adolescents with severe obesity","volume":"101","author":"Kalra M.","year":"1998","journal-title":"Pediatrics"},{"key":"e_1_2_10_151_2","first-page":"675","article-title":"The effects of a high\u2010protein, low\u2010fat, ketogenic diet on adolescents with morbid obesity: body composition, blood chemistries, and sleep abnormalities","volume":"18","author":"Willi S.M.","year":"2008","journal-title":"Obes. Surg."},{"key":"e_1_2_10_152_2","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1007\/s00125-011-2184-7","article-title":"Disturbed subjective sleep characteristics in adult patients with long\u2010standing type 1 diabetes mellitus","volume":"54","author":"van Dijk M.","journal-title":"Diabetologia"},{"key":"e_1_2_10_153_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.66"},{"key":"e_1_2_10_154_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2009.04.007"},{"key":"e_1_2_10_155_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039693"},{"key":"e_1_2_10_156_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2869.1999.00158.x"},{"key":"e_1_2_10_157_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00304.2005"},{"key":"e_1_2_10_158_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00026.2008"},{"key":"e_1_2_10_159_2","doi-asserted-by":"publisher","DOI":"10.1080\/07420520903044315"},{"key":"e_1_2_10_160_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2000.00695.x"},{"key":"e_1_2_10_161_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3000741"},{"key":"e_1_2_10_162_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12199-011-0222-1"},{"key":"e_1_2_10_163_2","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-1088"},{"key":"e_1_2_10_164_2","doi-asserted-by":"publisher","DOI":"10.1210\/endo.141.2.7311"},{"key":"e_1_2_10_165_2","first-page":"588","article-title":"Disrupted chronobiology of sleep and cytoprotection in obesity: possible therapeutic value of melatonin","volume":"32","author":"Cardinali D.P.","year":"2011","journal-title":"Neuro. Endocrinol. Lett."},{"key":"e_1_2_10_166_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2007.00527.x"},{"key":"e_1_2_10_167_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2106-8"},{"key":"e_1_2_10_168_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.290"},{"key":"e_1_2_10_169_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.1053"},{"key":"e_1_2_10_170_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2005.00287.x"},{"key":"e_1_2_10_171_2","first-page":"307","article-title":"Efficacy and safety of prolonged\u2010release melatonin in insomnia patients with diabetes: a randomized, double\u2010blind, crossover study","volume":"4","author":"Garfinkel D.","year":"2011","journal-title":"Diabetes Metab. Syndr. Obes."},{"key":"e_1_2_10_172_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2010.00835.x"},{"key":"e_1_2_10_173_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2008.00561.x"},{"key":"e_1_2_10_174_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/27.7.1255"},{"key":"e_1_2_10_175_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2008.0841"},{"key":"e_1_2_10_176_2","first-page":"1191","article-title":"Sleep disorders and medical conditions in women. 2008. Proceedings of the Women &\n\t\t\t\t\t\tSleep Workshop, National Sleep Foundation, Washington, DC, March 5\u20136, 2007","volume":"17","author":"Philips B.A.","journal-title":"J. Womens Health"},{"key":"e_1_2_10_177_2","doi-asserted-by":"publisher","DOI":"10.1177\/193229680900300418"},{"key":"e_1_2_10_178_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2008.02.024"},{"issue":"5","key":"e_1_2_10_179_2","first-page":"S6","article-title":"Impact of sleepiness and sleep deficiency on public health\u2010utility of biomarkers","volume":"7","author":"Czeisler C.A.","year":"2011","journal-title":"J. Clin. Sleep Med."},{"key":"e_1_2_10_180_2","doi-asserted-by":"publisher","DOI":"10.1177\/1740774510368298"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1749-6632.2012.06655.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1749-6632.2012.06655.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/j.1749-6632.2012.06655.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1749-6632.2012.06655.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T17:18:20Z","timestamp":1695662300000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.2012.06655.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,24]]},"references-count":179,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1111\/j.1749-6632.2012.06655.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1749-6632.2012.06655.x","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,24]]}}}