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The MGC, which takes less than five minutes to complete, is made up of three ocular, three bulbar, one respiratory, one neck, and two limb items. After its construction, the MGC was validated in an 11\u2010center scale validity study. During the validation study, which included test\u2013retest analysis, it was determined that a 3\u2010point improvement in MGC score reliably indicates clinical improvement. A 3\u2010point improvement in MGC also appears to be meaningful to the patient. Rasch analysis of the MGC confirmed that all 10 items belong and can be summed to provide a total score, and that the weights given to the response categories of the items are appropriate.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2012.06812.x","type":"journal-article","created":{"date-parts":[[2012,12,18]],"date-time":"2012-12-18T19:02:49Z","timestamp":1355857369000},"page":"99-106","source":"Crossref","is-referenced-by-count":38,"title":["The MG composite: an outcome measure for myasthenia gravis for use in clinical trials and everyday practice"],"prefix":"10.1111","volume":"1274","author":[{"given":"Ted M.","family":"Burns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,17]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70063-8"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198703193161205"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00314245"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1993.tb22937.x"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb11015.x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.7.1487"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.1.16"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050585"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1254.056"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1254.057"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1254.058"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000163988.28892.79"},{"key":"e_1_2_9_14_2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10072-004-0366-5","article-title":"Myasthenia gravis self\u2010administered questionnaire: development of regional domains","volume":"25","author":"Padua L.","year":"2005","journal-title":"Neurol. 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