{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:27:12Z","timestamp":1788280032433,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,17]],"date-time":"2012-12-17T00:00:00Z","timestamp":1355702400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>The myasthenia gravis activities of daily living (MG\u2010ADL) profile is an eight\u2010item patient\u2010reported scale developed to assess MG symptoms and their effects on daily activities. The MG\u2010ADL profile correlated well with the Quantitative MG (QMG) score (<jats:italic>r<\/jats:italic>= 0.58, <jats:italic>P<\/jats:italic> &lt; 0.001) in 254 consecutive patient visits. Further analysis during clinical trials confirmed the excellent correlation with the QMG test and provided additional evidence that the MG\u2010ADL profile is responsive to clinical improvement. MG\u2010ADL performance was further analyzed during a recent multicenter, prospective scale validation study for two new outcome measures. At the first visit, there was a strong positive correlation between the MG\u2010ADL and the MG Composite (<jats:italic>r<\/jats:italic>= 0.85, <jats:italic>P<\/jats:italic> &lt; 0.0001) and between the MG\u2010ADL and the MG\u2010Quality of life15 (MG\u2010QOL15) (<jats:italic>r<\/jats:italic>= 0.76, <jats:italic>P<\/jats:italic> &lt; 0.0001). Test\u2013retest analysis demonstrated a high reliability coefficient. Sensitivity\/specificity analysis revealed that a 2\u2010point improvement has the best trade\u2010off attributes to predict clinical improvement. The MG\u2010ADL profile also performed well on Rasch analysis. The MG\u2010ADL scoring system is useful as a secondary outcome measure and in routine clinical management.<\/jats:p>","DOI":"10.1111\/j.1749-6632.2012.06817.x","type":"journal-article","created":{"date-parts":[[2012,12,18]],"date-time":"2012-12-18T19:02:49Z","timestamp":1355857369000},"page":"114-119","source":"Crossref","is-referenced-by-count":66,"title":["The Myasthenia Gravis\u2010Specific Activities of Daily Living Profile"],"prefix":"10.1111","volume":"1274","author":[{"given":"Srikanth","family":"Muppidi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,17]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21713"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb11015.x"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.7.1487"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000147242.92691.71"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10224"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1185\/030079904125004385"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10472"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.47.0513"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000312374.95186.cc"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000312373.67493.7f"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21142"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dc1b1e"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21883"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22140"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1254.061"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1749-6632.2012.06817.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1749-6632.2012.06817.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T06:18:23Z","timestamp":1695017903000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.2012.06817.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/j.1749-6632.2012.06817.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1749-6632.2012.06817.x","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}