{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:43:10Z","timestamp":1761662590404},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,3,10]],"date-time":"2008-03-10T00:00:00Z","timestamp":1205107200000},"content-version":"vor","delay-in-days":11026,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:p><jats:bold>SUMMARY<\/jats:bold> Ten Droughtmaster and 9 Hereford cattle were born in an enzootic babesiasis area and became naturally infected with <jats:italic>Babesia argentina<\/jats:italic> and <jats:italic>B. bigemina<\/jats:italic> during a 3 year period. They were then kept free of cattle ticks <jats:italic>(Boophilus microplus)<\/jats:italic> for the remainder of the experiment.<\/jats:p><jats:p>Annually for the next 3 years their individual infection status with <jats:italic>Babesia<\/jats:italic> was determined by sub\u2010inoculation of blood into splenectomised calves. At the end of this period the functional immunity of all cattle was challenged by blood inoculation of heterologous strains of <jats:italic>B. argentina<\/jats:italic> and <jats:italic>B. bigemina<\/jats:italic>.<\/jats:p><jats:p>Infection with <jats:italic>B. argentina<\/jats:italic> persisted in all Herefords for 2 years and in 7 for 3 years after they had been freed of <jats:italic>B. microplus.<\/jats:italic> The number of Droughtmasters with detectable <jats:italic>B. argentina<\/jats:italic> infection progressively declined, and at the end of 3 years only 2 of 10 were still infected. No Herefords were shown to be infected with <jats:italic>B. bigemina<\/jats:italic> following 1 year's freedom from <jats:italic>B. microplus<\/jats:italic> but latent <jats:italic>B. bigemina<\/jats:italic> infection of at least 2 year's duration was demonstrated in one of the Droughtmasters.<\/jats:p><jats:p>A marked degree of resistance was apparent in all cattle when the were challenged with an heterologous strain of <jats:italic>B. argentina.<\/jats:italic> There were no differences between the response to challenge of the Herefords and Droughtmasters nor between the reactions of cattle which had apparently naturally sterilised <jats:italic>B. argentina<\/jats:italic> infection and those which were still infected. The heterologous strain of <jats:italic>B. bigemina<\/jats:italic> produced parasitaemia in the majority of animals but only minimal fever and anaemia resulted with no significant differences between the breeds.<\/jats:p>","DOI":"10.1111\/j.1751-0813.1978.tb00262.x","type":"journal-article","created":{"date-parts":[[2008,3,10]],"date-time":"2008-03-10T20:16:16Z","timestamp":1205180176000},"page":"14-18","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["THE DURATION OF LATENT INFECTION AND FUNCTIONAL IMMUNITY IN DROUGHTMASTER AND HEREFORD CATTLE FOLLOWING NATURAL INFECTION WITH <i>BABESIA ARGENTINA AND BABESIA BIGEMINA<\/i>"],"prefix":"10.1111","volume":"54","author":[{"given":"L. A. Y.","family":"Johnston","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Leatch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,3,10]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1961.tb03857.x"},{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1974.tb09359.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1974.tb09361.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/217267a0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1955.tb05543.x"},{"key":"e_1_2_1_6_1","first-page":"V","volume":"87","author":"Hoyte H. M. D.","year":"1976","journal-title":"Proc. R. Soc. Qd."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1967.tb08866.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1968.tb04975.x"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1968.tb09131.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1961.tb03838.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1973.11686877"},{"key":"e_1_2_1_12_1","unstructured":"Queensland Bureau of Census and Statistics(1973)\u2014Bulletin Q161\/73 Beef Cattle Breeds."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1971.tb02166.x"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1751-0813.1978.tb00262.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1751-0813.1978.tb00262.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T13:14:42Z","timestamp":1696684482000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1751-0813.1978.tb00262.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1978,1]]}},"alternative-id":["10.1111\/j.1751-0813.1978.tb00262.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1751-0813.1978.tb00262.x","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1]]},"assertion":[{"value":"2008-03-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}