{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:19:41Z","timestamp":1782278381224,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,8,22]],"date-time":"2011-08-22T00:00:00Z","timestamp":1313971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p><jats:bold>Objective\u2003<\/jats:bold>To describe the use of intralesional amphotericin B in localised lesions for the treatment of 26 cats from Rio de Janeiro, Brazil, with sporotrichosis refractory to oral itraconazole.<\/jats:p><jats:p><jats:bold>Design\u2003<\/jats:bold>Uncontrolled intervention study.<\/jats:p><jats:p><jats:bold>Method\u2003<\/jats:bold>The 26 cats in this study were diagnosed with sporotrichosis, confirmed by isolation of<jats:italic>Sporothrix schenckii<\/jats:italic>, and presented residual localised skin lesions refractory to treatment with oral itraconazole for a minimum period of 8 weeks. The animals received weekly applications of intralesional amphotericin B in conjunction with oral itraconazole. In cases of owner unavailability, a maximum of 2 weeks between the infiltrations was accepted.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold>Twenty\u2010two (84.6%) of the 26 treated cats achieved clinical remission, 16 (72.7%) of which were cured, and in the remaining six (27.3%) the lesions recurred at the same site. Lack of clinical response was observed in one animal and three owners abandoned treatment.<\/jats:p><jats:p><jats:bold>Conclusion\u2003<\/jats:bold>The proposed therapeutic regimen is an adjunctive treatment option for cats with sporotrichosis presenting as residual skin lesions refractory to itraconazole.<\/jats:p>","DOI":"10.1111\/j.1751-0813.2011.00804.x","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T12:31:20Z","timestamp":1444739480000},"page":"346-351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole"],"prefix":"10.1111","volume":"89","author":[{"given":"IDF","family":"Gremi\u00e3o","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TMP","family":"Schubach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SA","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AM","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CO","family":"Honse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MBL","family":"Barros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,22]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"325","volume-title":"Medical mycology \u2013 The pathogenic fungi and pathogenic actinomycetes","author":"Rippon J","year":"1988"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.1623"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.22456\/1679-9216.16781","article-title":"Aspectos terap\u00eauticos da esporotricose felina","volume":"37","author":"Pereira SA","year":"2009","journal-title":"Acta Sci Vet"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3282f44c52"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/649891"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/381200"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.1123"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.166.10.290"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01087.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2004.02.001"},{"key":"e_1_2_6_12_2","first-page":"542","volume-title":"Infectious Diseases of the Dog and Cat","author":"Greene CE","year":"2006"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1993.tb03168.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb01512.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)80325-9"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70139-4"},{"key":"e_1_2_6_17_2","first-page":"3","article-title":"Sporotrichosis in a cat","volume":"16","author":"Mackay BM","year":"1986","journal-title":"Aust Vet Pract"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.01.012"},{"key":"e_1_2_6_19_2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.22456\/1679-9216.15281","article-title":"Tratamento cir\u00fargico associado \u00e0 terapia antif\u00fangica convencional na esporotricose felina","volume":"34","author":"Gremi\u00e3o IDF","year":"2006","journal-title":"Acta Sci Vet"},{"key":"e_1_2_6_20_2","first-page":"69","article-title":"Procedimento operacional padr\u00e3o para o manejo de gatos com suspeita de esporotricose","volume":"65","author":"Gremi\u00e3o IDF","year":"2006","journal-title":"Clin Vet"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00763.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1996.tb10003.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1959.01560140046007"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1959.03010320051012"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1967.tb11505.x"},{"key":"e_1_2_6_26_2","first-page":"326","article-title":"Chromoblastomycosis of the ear. 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