{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T15:07:49Z","timestamp":1772032069226,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T00:00:00Z","timestamp":1199232000000},"content-version":"vor","delay-in-days":5055,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photochem &amp; Photobiology"],"published-print":{"date-parts":[[1994,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to evaluate the effect of light on helper\u2010 and suppressor\u2010T\u2010cell counts in HIV\u2010infected individuals, with and without a history of seasonal affective disorder (SAD), we treated 35 subjects with 45 min of light therapy in the morning, in a crossover design involving two 2 week treatment conditions: visible white light (half\u2010peak band width, 530\u2010620 nm; 10 000 lux) and visible red light (half\u2010peak band width, 615\u2010685 nm; 175 lux). We found small but significant differences between the two treatment conditions, with higher CD4 and CD8 levels during the white, as compared with the red, condition. There were no differences between baseline and treatment conditions. Both light treatment conditions were associated with significant mood improvements in the SAD, but not the non\u2010SAD, subjects. There was no evidence that the higher cell counts seen under the bright light conditions were mediated by the effects of light on mood or on plasma Cortisol levels. While the size of the light effect on T\u2010cells renders questionable the potential therapeutic value of this treatment modality for HIV, the finding is of theoretical interest and is reassuring for those HIV\u2010infected individuals who require light treatment for other reasons.<\/jats:p>","DOI":"10.1111\/j.1751-1097.1994.tb05040.x","type":"journal-article","created":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T19:52:38Z","timestamp":1199303558000},"page":"314-319","source":"Crossref","is-referenced-by-count":8,"title":["EFFECTS OF LIGHT ON T\u2010CELLS IN HIV\u2010INFECTED SUBJECTS ARE NOT DEPENDENT ON HISTORY OF SEASONAL AFFECTIVE DISORDER"],"prefix":"10.1111","volume":"59","author":[{"given":"Norman E.","family":"Rosenthal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan A.","family":"Oren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Galetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D.","family":"Malley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,1,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1985.tb11802.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0210213"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7434030"},{"key":"e_1_2_1_5_2","first-page":"99","volume-title":"Sleep and Biological Rhythms","author":"Lewy A.","year":"1990"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2734611"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1984.01790120076010"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0893-133X(89)90002-X"},{"key":"e_1_2_1_9_2","first-page":"551","volume-title":"Handbook of Affective Disorders","author":"Oren D. 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