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In this work we investigated effects of LLLT and diclofenac on functional outcomes in the acute stage after muscle strain injury in rats. Muscle strain was induced by overloading the tibialis anterior muscle of rats during anesthesia. The injured groups received either no treatment, or a single treatment with diclofenac 30\u2003min prior to injury, or LLLT (810\u2003nm, 100\u2003mW) with doses of 1, 3, 6 or 9\u2003J, at 1\u2003h after injury. Functional outcome measures included a walking index and assessment of electrically induced muscle performance. All treatments (except 9\u2003J LLLT) significantly improved the walking index 12\u2003h postinjury compared with the untreated group. The 3\u2003J group also showed a significantly better walking index than the drug group. All treatments significantly improved muscle performance at 6 and 12\u2003h. LLLT dose of 3\u2003J was as effective as the pharmacological agent in improving functional outcomes in the early phase after a muscle strain injury in rats.<\/jats:p>","DOI":"10.1111\/j.1751-1097.2011.01030.x","type":"journal-article","created":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T15:09:31Z","timestamp":1320419371000},"page":"154-160","source":"Crossref","is-referenced-by-count":29,"title":["Infrared (810\u2003nm) Low\u2010Level Laser Therapy in Experimental Model of Strain\u2010Induced Skeletal Muscle Injury in Rats: Effects on Functional Outcomes"],"prefix":"10.1111","volume":"88","author":[{"given":"Luciano","family":"Ramos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto Cesar Pinto","family":"Leal Junior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney Capp","family":"Pallotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucio","family":"Frigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Labat","family":"Marcos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Helena Catelli","family":"de Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Magnus","family":"Bjordal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo \u00c1lvaro Brand\u00e3o","family":"Lopes\u2010Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,11,22]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1177\/036354659602406S02","article-title":"Muscle strain injuries","volume":"24","author":"Garret W. 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