{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:15:19Z","timestamp":1793646919189,"version":"4.5.1"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,5,24]],"date-time":"2012-05-24T00:00:00Z","timestamp":1337817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Digest Diseases"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:bold>OBJECTIVE:\u2003<\/jats:bold> This study was aimed to evaluate the prevalence of eosinophilic esophagitis (EoE) among patients with esophageal or upper gastrointestinal (UGI) symptoms.<\/jats:p><jats:p><jats:bold>METHODS:\u2003<\/jats:bold> Patients with esophageal or UGI symptoms including dysphagia food impaction, acid regurgitation, heartburn, chest pain, epigastric pain, nausea and\/or vomiting were prospectively collected. The enrolled patients responded to a symptomatic questionnaire and underwent an esophagogastroduodenoscopy and esophageal biopsies. Supportive endoscopic findings of EoE (ring\u2010like appearance, liner furrows, whitish papules, shearing or friability) were recorded. EoE was diagnosed if patients had chronic UGI or esophageal symptoms, the esophageal biopsy showed \u226515 eosinophils\/high\u2010power field and were unresponsive to 2\u20133 weeks of proton pump inhibitors.<\/jats:p><jats:p><jats:bold>RESULTS:\u2003<\/jats:bold> A total of 122 patients were enrolled and supportive endoscopic findings were found in 31 (25.4%) patients [whitish papules: 19 (15.6%), ring\u2010like appearance: 8 (6.6%), linear furrows: 5 (4.1%)]. One patient had a simultaneous ring\u2010like appearance and linear furrows. EoE was diagnosed in 8 (6.6%) patients and supportive endoscopic findings and past history of gastroesophageal reflux disease, allergic rhinitis and atopic dermatitis were more common in EoE positive than EoE negative patients. The diagnostic yield of endoscopic findings was 40.0% (2\/5) in linear furrows, 25.0% (2\/8) in ring\u2010like appearance and 15.8% (3\/19) in whitish papules.<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2003<\/jats:bold> Prevalence of EoE among patients with esophageal or UGI symptoms was 6.6%. Linear furrows and ring\u2010like appearance had a relatively high diagnostic value.<\/jats:p>","DOI":"10.1111\/j.1751-2980.2012.00589.x","type":"journal-article","created":{"date-parts":[[2012,2,27]],"date-time":"2012-02-27T12:16:12Z","timestamp":1330344972000},"page":"296-303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Prevalence and endoscopic features of eosinophilic esophagitis in patients with esophageal or upper gastrointestinal symptoms"],"prefix":"10.1111","volume":"13","author":[{"given":"Moon Kyung","family":"JOO","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Jae","family":"PARK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Ho","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Key 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