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The adjunctive use of locally delivered antimicrobials has been proven to be beneficial, especially in areas where mechanical therapy might fail. This article describes the management of a patient with DS who had aggressive periodontitis. The treatment used a local drug delivery system with tetracycline fibers as an adjunct to scaling and root planing.<\/jats:p>","DOI":"10.1111\/j.1754-4505.2012.00237.x","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T03:49:05Z","timestamp":1331783345000},"page":"61-65","source":"Crossref","is-referenced-by-count":6,"title":["Adjunctive use of tetracycline fibers with nonsurgical periodontal therapy in an adult with Down syndrome: a case report"],"prefix":"10.1111","volume":"32","author":[{"given":"Penmetsa Subadhra","family":"Gautami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alluri Venkata","family":"Ramaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madiraju","family":"GunaShekhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,15]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"E211","article-title":"Periodontal disease associated to systemic genetic disorders","volume":"12","author":"Nualart Grollmus ZC","year":"2007","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_5_3_2","first-page":"139","article-title":"The oral cavity in Down syndrome","volume":"14","author":"Borea G","year":"1990","journal-title":"J Pedod"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.3.368"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.3104\/reports.1998"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2010.00134.x"},{"key":"e_1_2_5_7_2","first-page":"201","article-title":"Chlorhexidine chip and tetracycline fibers as adjunct to scaling and root planing: a clinical study","volume":"8","author":"Srivastava R","year":"2009","journal-title":"Braz J Oral Sci"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01122.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00620.x"},{"key":"e_1_2_5_10_2","first-page":"70","volume-title":"Periodontal instrumentation","author":"Pattison AM","year":"1992"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540460058033"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.7.1061"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1387"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.1992.tb01220.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/104454704773660912"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2004.00763.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.72.9.1241"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.3.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.85668"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb01767.x"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572010000600017"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.6.916"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.11.1029"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070247"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.9.s1.11.x"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1754-4505.2012.00237.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1754-4505.2012.00237.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T02:19:27Z","timestamp":1698632367000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1754-4505.2012.00237.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1111\/j.1754-4505.2012.00237.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1754-4505.2012.00237.x","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}