{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:44:41Z","timestamp":1773927881694,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,3,6]],"date-time":"2012-03-06T00:00:00Z","timestamp":1330992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Primary central nervous system lymphoma (PCNSL) is an uncommon but important variant of non\u2010Hodgkin lymphoma and represents up to 6% of all primary central nervous system (CNS) malignancies. Recognition of this entity by radiologist on MRI may avoid unnecessary neurosurgical resection and redirect to biopsy. The pretreatment MRI of patients with biopsy proven PCNSL from the last 5\u2003years at our institution was reviewed. Selected examples were used to construct a pictorial essay to illustrate some of the typical and atypical MR features of PCNSL. MRI of other CNS conditions with imaging similarities to PCNSL was included to demonstrate possible mimics. The typical features of PCNSL lymphoma are intra\u2010axial homogenous single or multiple contrast enhancing lesions, with marked surrounding oedema and restricted diffusion, usually contacting a cerebrospinal fluid (CSF) surface. Necrosis, peripheral enhancement, haemorrhage or calcification are unusual and other diagnoses should be considered if any of these features are present. Potential mimics include high grade glioma, infarcts, metastatic disease, demyelination, abscess and secondary lymphoma. Careful assessment of the MR features and correlation with the clinical findings should enable the radiologists to raise the possibility of PCNSL and minimise the risk of unnecessary resection.<\/jats:p>","DOI":"10.1111\/j.1754-9485.2012.02345.x","type":"journal-article","created":{"date-parts":[[2012,3,7]],"date-time":"2012-03-07T03:16:13Z","timestamp":1331090173000},"page":"179-186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Magnetic resonance features of primary central nervous system lymphoma in the immunocompetent patient: A pictorial essay"],"prefix":"10.1111","volume":"56","author":[{"given":"Kelvin K","family":"Yap","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaine","family":"Liew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Con J","family":"Tartaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Trost","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,6]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2004.10.007"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22989"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-004-3390-7"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1447"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70091-2"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2171"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.3.393"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-010-0258-x"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00593213"},{"issue":"10","key":"e_1_2_9_11_2","first-page":"2446","article-title":"Radiologic morphology of low\u2010grade primary central nervous system lymphoma in immunocompetent patients","volume":"26","author":"Jahnke K","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-001-0024-6"},{"issue":"3","key":"e_1_2_9_13_2","first-page":"563","article-title":"The variable MR appearance of primary lymphoma of the central nervous system: comparison with histopathologic features","volume":"18","author":"Johnson BA","year":"1997","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"e_1_2_9_14_2","first-page":"1207","article-title":"MR of primary CNS lymphoma in immunologically normal patients","volume":"13","author":"Roman\u2010Goldstein SM","year":"1992","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2007.00231.x"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2006.02.001"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1754-9485.2012.02345.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1754-9485.2012.02345.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T00:22:37Z","timestamp":1697329357000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1754-9485.2012.02345.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,6]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1754-9485.2012.02345.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1754-9485.2012.02345.x","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,6]]},"assertion":[{"value":"2012-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}