{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:40:33Z","timestamp":1761561633043},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T00:00:00Z","timestamp":1334016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective:<\/jats:bold> To evaluate the prevalence of <jats:italic>Schistosoma mansoni<\/jats:italic>\u2010related liver disease in school\u2010age children who live beside the Zambezi River in the Chitokoloki district, North Western Province, Zambia.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Liver ultrasounds of school students from the Chitokoloki day school, grades 1\u201312, were performed. Liver patterns, periportal branch wall thickening and portal hypertension were assessed to evaluate the presence of liver fibrosis due to <jats:italic>S. mansoni<\/jats:italic> infection. To obtain incidence rates of acute disease, stool specimens were examined from a subgroup for the presence of <jats:italic>S. mansoni<\/jats:italic> eggs using the formol detergent sedimentation technique.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Of 976 enrolled students, 764 (78.2%) were examined by ultrasound. Of those, 284 (37.2%) had findings indicative of periportal fibrosis on ultrasound. Stool specimen were collected from 414 (54%) students of which six (1.5%) were positive for <jats:italic>S.\u2003mansoni<\/jats:italic> eggs.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> School students living along the Zambezi River, Zambia have a relatively high prevalence of <jats:italic>S. mansoni<\/jats:italic>\u2010related liver disease. These findings suggest that all schoolchildren in this area should receive treatment against <jats:italic>S. mansoni<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/j.1754-9485.2012.02371.x","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T07:45:24Z","timestamp":1334043924000},"page":"390-397","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Ultrasound study of liver disease caused by <i>Schistosoma mansoni<\/i> in rural Zambian schoolchildren"],"prefix":"10.1111","volume":"56","author":[{"given":"Rodney","family":"Strahan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kan' ombi","family":"Chiyesu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal E","family":"Schneider\u2010Kolsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,10]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"221","volume-title":"Livingstone's African Journal 1853\u20131856","author":"Schapera I","year":"1963"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16728-7"},{"key":"e_1_2_6_4_2","first-page":"269","article-title":"Schistosomiasis in Zambia: an historical overview and review of the literature","volume":"18","author":"Michelson EH","year":"1989","journal-title":"Afr J Med Med Sci"},{"key":"e_1_2_6_5_2","unstructured":"MwanakasaleV.Research Network for Schistosomiasis in Africa RNSA. 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