{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:34:15Z","timestamp":1785368055602,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,7,9]],"date-time":"2012-07-09T00:00:00Z","timestamp":1341792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><\/jats:sec><jats:sec><jats:label\/><jats:p>To describe clinical characteristics of fibromyalgia in an Australian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data was collected from 150 consecutive patients with clinical features of fibromyalgia seen in an Australian public hospital clinic. Demographic information and clinical characteristics were recorded. Significant correlations between clinical characteristics were identified, then used in multiple regression analyses to identify factors influencing outcome in physical function, pain, fatigue and sleep disturbance. Clinical features in groups who were or were not using different treatment strategies were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most patients were female and Caucasian. The majority reported a recognizable trigger factor and many had associated conditions, most commonly headache and irritable bowel syndrome. Physical function was significantly accounted for by pain levels (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001); pain score was significantly predicted by tenderness (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.002) and physical function level (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001); fatigue levels were significantly influenced by age (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.007) and sleep disturbance (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and sleep disturbance was significantly predicted by fatigue (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Just over one\u2010third (34%) of patients were using fibromyalgia medications (low\u2010dose tricyclic antidepressant, pregabalin or duloxetine); however, they had less anxiety (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.006) and better reported physical function (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) than those who were not. Less than half (43.6%) of the patients were regularly exercising; however, they had reduced overall illness impact scores (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.004), better physical function (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.01) and less fatigue (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03), anxiety (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02) and depressive features (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.008) than non\u2010exercisers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Baseline clinical characteristics in this group were comparable to other study populations. The use of management modalities with proven benefit in fibromyalgia was limited; however, those patients who were engaged in regular exercise or using medication had better self\u2010reported outcome measures than those who were not.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1756-185x.2012.01767.x","type":"journal-article","created":{"date-parts":[[2012,7,9]],"date-time":"2012-07-09T05:10:54Z","timestamp":1341810654000},"page":"348-357","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical characteristics of 150 consecutive fibromyalgia patients attending an Australian public hospital clinic"],"prefix":"10.1111","volume":"15","author":[{"given":"Emma K.","family":"Guymer","sequence":"first","affiliation":[{"name":"Department of Rheumatology Monash Medical Centre  Clayton Victoria Australia"},{"name":"Department of Medicine Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Maruff","sequence":"additional","affiliation":[{"name":"Centre for Neuroscience University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey O.","family":"Littlejohn","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Monash Medical Centre  Clayton Victoria Australia"},{"name":"Department of Medicine Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.60.11.1040"},{"key":"e_1_2_8_3_1","first-page":"1577","article-title":"The London Fibromyalgia Epidemiology Study: comparing the demographic and clinical characteristics in 100 random community cases of fibromyalgia versus controls","volume":"26","author":"White KP","year":"1999","journal-title":"J Rheumatol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780380104"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01638.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01480.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330203"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780401103"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.4065\/74.4.385"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-002-0038-5"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(96)80011-4"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20042"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi013"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1006\/nbdi.1999.0262"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-002-0260-5"},{"key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/sj.mp.4001568","article-title":"An association between fibromyalgia and the dopamine D4 receptor exon III repeat polymorphism and relationship to novelty seeking personality traits","volume":"9","author":"Buskila D","year":"2004","journal-title":"Mol Psychiatry"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-05468-6_5"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.41.2.104"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20485"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.02.024"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2008.11.009"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080734"},{"key":"e_1_2_8_23_1","first-page":"502","article-title":"A randomized, double\u2010blind, placebo\u2010controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia","volume":"35","author":"Mease PJ","year":"2008","journal-title":"J Rheumatol"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20983"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.02.027"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003786.pub2"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02908299"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-001-0009-2"},{"key":"e_1_2_8_29_1","first-page":"1280","article-title":"Improving physical functional status in patients with fibromyalgia: a brief cognitive behavioral intervention","volume":"29","author":"Williams DA","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22778"},{"key":"e_1_2_8_31_1","unstructured":"Australian Institute of Health and Welfare website.Table S13:Selected health conditions by disability status and age group Australia 2007\u201308 (percent). Australian Institute of Health and Welfare website Australian Government 2010 (Accessed 11 December 2010)."},{"key":"e_1_2_8_32_1","first-page":"728","article-title":"The fibromyalgia impact questionnaire: development and validation","volume":"18","author":"Burckhardt CS","year":"1991","journal-title":"J Rheumatol"},{"key":"e_1_2_8_33_1","first-page":"S154","article-title":"The Fibromyalgia Impact Questionnaire (FIQ): a review of its development, current version, operating characteristics and uses","volume":"23","author":"Bennett R","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20140"},{"key":"e_1_2_8_35_1","first-page":"151","article-title":"Aspects of fibromyalgia in the general population: sex, pain threshold, and fibromyalgia symptoms","volume":"22","author":"Wolfe F","year":"1995","journal-title":"J Rheumatol"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.100594"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/art1.10180"},{"key":"e_1_2_8_38_1","first-page":"714","article-title":"A randomized, controlled clinical trial of education and physical training for women with fibromyalgia","volume":"21","author":"Burckhardt CS","year":"1994","journal-title":"J Rheumatol"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.4065\/81.6.749"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00116-5"},{"key":"e_1_2_8_41_1","first-page":"1130","article-title":"Exercise for fibromyalgia: a systematic review","volume":"35","author":"Busch AJ","year":"2008","journal-title":"J Rheumatol"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2010"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-11-134"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1756-185X.2012.01767.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1756-185X.2012.01767.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T06:37:30Z","timestamp":1698734250000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1756-185X.2012.01767.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,9]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1111\/j.1756-185X.2012.01767.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1756-185x.2012.01767.x","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,9]]},"assertion":[{"value":"2012-07-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}