{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T17:41:44Z","timestamp":1770054104733,"version":"3.49.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,30]],"date-time":"2012-01-30T00:00:00Z","timestamp":1327881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopaedic Surgery"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p><jats:bold>Objectives:\u2002<\/jats:bold> To study the long\u2010term outcomes of inactivated bone reimplantation with preservation of the epiphysis in children with distal femoral osteosarcomas.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Over 10 years, five children (mean age 9.2 years, one boy and four girls) with distal femoral osteosarcomas underwent inactivated bone reimplantation with preservation of the epiphysis following chemotherapy in our hospital. Three patients were type I on MRI classification (one with pathological fracture), and two type II. The therapeutic regime was two cycles of preoperative chemotherapy, surgery and six cycles of postoperative chemotherapy.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Five patients were followed up for 60\u2013126 months (mean 82 months). No local tumor recurrences or metastases occurred. Three patients with fractures of inactivated bone were treated by open reduction, bone grafting and internal fixation; their fractures had united by 6 months after reoperation. The mean functional score of the affected limbs was 25.6 points (13\u201330 points).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Inactivated bone reimplantation with preservation of the epiphysis for distal femoral osteosarcomas in children optimizes recovery of limb function and preservation of limb length. The main measures for improving clinical outcomes include preoperative analysis of the lesion's boundaries and extent of tumor invasion, bone grafting between inactivated and host bone, and timely treatment of complications.<\/jats:p>","DOI":"10.1111\/j.1757-7861.2011.00167.x","type":"journal-article","created":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T00:55:16Z","timestamp":1327971316000},"page":"21-27","source":"Crossref","is-referenced-by-count":15,"title":["Long\u2010term outcomes of epiphyseal preservation and reconstruction with inactivated bone for distal femoral osteosarcoma of children"],"prefix":"10.1111","volume":"4","author":[{"given":"Xiu\u2010chun","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song\u2010feng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruo\u2010xian","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,30]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"565","article-title":"Inactivated bone replantation with preservation of the epiphysis: clinical report of two cases and literature review (Chin)","volume":"23","author":"Yu XC","year":"2002","journal-title":"Zhonghua Xiao Er Wai Ke Za Zhi"},{"key":"e_1_2_6_3_2","first-page":"874","article-title":"Value of MRI for detecting epiphyseal extension of osteosarcoma (Chin)","volume":"11","author":"Yu XC","year":"2003","journal-title":"Zhongguo Jiao Xing Wai Ke Za Zhi"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199301000-00035"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B1.8300655"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199901000-00014"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.84B8.13330"},{"key":"e_1_2_6_8_2","first-page":"813","article-title":"Limb salvage surgery for malignant bone tumor of the extremities (Chin)","volume":"26","author":"Wang Z","year":"2006","journal-title":"Zhonghua Gu Ke Za Zhi"},{"key":"e_1_2_6_9_2","first-page":"811","article-title":"Epiphyseal preservation and reconstruction with inactivated bone in distal femur for metaphyseal osteosarcoma in children (Chin)","volume":"15","author":"Yu XC","year":"2007","journal-title":"Zhongguo Jiao Xing Wai Ke Za Zhi"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.E.00253"}],"container-title":["Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1757-7861.2011.00167.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1757-7861.2011.00167.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:42:46Z","timestamp":1698644566000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1757-7861.2011.00167.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,30]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1111\/j.1757-7861.2011.00167.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1757-7861.2011.00167.x","archive":["Portico"],"relation":{},"ISSN":["1757-7853","1757-7861"],"issn-type":[{"value":"1757-7853","type":"print"},{"value":"1757-7861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,30]]}}}