{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T17:47:34Z","timestamp":1759513654812},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,3,12]],"date-time":"2008-03-12T00:00:00Z","timestamp":1205280000000},"content-version":"vor","delay-in-days":1928,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Background: The aim of this study was to evaluate the comparative efficacy of three commonly used analgesics (Panadeine, Diflunisal and Etodolac) in the control of pain after third molar surgery under local anaesthesia.<\/jats:p><jats:p>Methods: A randomized control study. Outcome of primary efficacy was judged by overall assessment of the area under the curve of graphs for pain intensity, measured from serial visual analogue scales over a 24\u2010hour period. Other measures of efficacy included the number (per cent) of patients who took \u2018additional\u2019 analgesics and the incidence of adverse effects occurring in each treatment group over the study period.<\/jats:p><jats:p>Results: The three drugs were effective in the control of post\u2010operative pain (p&lt;0.01). Variations in pain intensity and the use of additional medication between the treatment groups were observed over the study period. The Diflunisal group experienced less pain than the Panadeine or Etodolac group (p&lt;0.01). Furthermore, a lesser number of those in the Diflunisal group used additional medication compared to the other two groups (p&lt;0.01). The incidence of side effects from all three drugs was low.<\/jats:p><jats:p>Conclusion: Diflunisal is superior in the control of pain following third molar surgery under local anaesthesia than either Panadeine or Etodolac, and has few side effects.<\/jats:p>","DOI":"10.1111\/j.1834-7819.2002.tb00546.x","type":"journal-article","created":{"date-parts":[[2008,3,12]],"date-time":"2008-03-12T10:43:31Z","timestamp":1205318611000},"page":"327-330","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A study of the comparative efficacy of three common analgeisics in the control of pain after third molar surgery under local anaesthesia"],"prefix":"10.1111","volume":"47","author":[{"given":"MB","family":"Comfort","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ASK","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ACC","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"McGrath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,3,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-4356(93)90191-X"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(84)80017-4"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4806453"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1992.0180"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4804524"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4809512"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1986.0098"},{"key":"e_1_2_1_9_2","first-page":"1","volume-title":"The complete drug reference","author":"Parfitt K.","year":"1999"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4809081"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.313.7053.321"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4804728"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(87)80107-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(86)90255-0"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(86)90150-3"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(83)90070-1"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-4356(85)90025-7"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(90)90396-A"},{"key":"e_1_2_1_19_2","first-page":"103","volume-title":"The mouth, the face and the mind","author":"Feinmann C.","year":"1999"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1993.tb05474.x"},{"key":"e_1_2_1_21_2","first-page":"389","volume-title":"Human pharmacology: molecular to clinical","author":"Brody TM.","year":"1994"},{"key":"e_1_2_1_22_2","first-page":"96","volume-title":"Aspirin and the salicylates","author":"Rainsford KD.","year":"1984"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1977.tb04511.x"}],"container-title":["Australian Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1834-7819.2002.tb00546.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1834-7819.2002.tb00546.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T12:47:22Z","timestamp":1700311642000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1834-7819.2002.tb00546.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1111\/j.1834-7819.2002.tb00546.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1834-7819.2002.tb00546.x","archive":["Portico"],"relation":{},"ISSN":["0045-0421","1834-7819"],"issn-type":[{"value":"0045-0421","type":"print"},{"value":"1834-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,12]]},"assertion":[{"value":"2008-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}