{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:29:14Z","timestamp":1793240954708,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,8,11]],"date-time":"2011-08-11T00:00:00Z","timestamp":1313020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> The aim of this study was to evaluate the cardiovascular effects of maxillary infiltration using 2% lidocaine with 1:100\u200a000 adrenaline, 4% articaine with 1:200\u200a000 adrenaline, and 4% articaine with 1:100\u200a000 adrenaline in different stages during restorative dental procedures.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Twenty healthy patients randomly received 1.8\u2003mL of the three local anaesthetics. Systolic blood pressure, average blood pressure, diastolic blood pressure, and heart rate were evaluated by the oscillometric and photoplethysmograph methods in seven stages during the appointment.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Statistical analysis by ANOVA and Tukey tests of cardiovascular parameters did not show significant differences between the anaesthetic associations. There were significant differences for the parameters among different clinical stages.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> The variation of cardiovascular parameters was similar for lidocaine and articaine with both adrenaline concentrations and showed no advantage of one drug over the other. Cardiovascular parameters were influenced by the stages of the dental procedures, which showed the effect of anxiety during restorative dental treatment.<\/jats:p>","DOI":"10.1111\/j.1834-7819.2011.01345.x","type":"journal-article","created":{"date-parts":[[2011,8,11]],"date-time":"2011-08-11T04:02:31Z","timestamp":1313035351000},"page":"312-316","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cardiovascular responses to different stages of restorative dental treatment unaffected by local anaesthetic type"],"prefix":"10.1111","volume":"56","author":[{"given":"CGC","family":"Bispo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IP","family":"Tortamano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RG","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CE","family":"Francischone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MA","family":"Borsatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"JCB","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ACR","family":"Medeiros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,11]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"29","article-title":"Local anesthetic update","volume":"40","author":"Mackenzie TA","year":"1993","journal-title":"Anesth Prog"},{"key":"e_1_2_7_3_2","volume-title":"Handbook of Local Anesthesia","author":"Malamed SF","year":"1997"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0237"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2001.0152"},{"key":"e_1_2_7_6_2","first-page":"77","article-title":"Intraoral conduction anesthesia with epinephrine\u2010containing local anesthetics and arterial epinephrine plasma concentration","volume":"1","author":"Sack U","year":"1992","journal-title":"Anesth Pain Control Dent"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0011-8532(02)00021-6"},{"key":"e_1_2_7_8_2","first-page":"161","article-title":"Local anaesthetics and vasoconstrictors in patients with compromised cardiovascular systems","volume":"41","author":"Anderson LD","year":"1993","journal-title":"Gen Dent"},{"key":"e_1_2_7_9_2","first-page":"546","article-title":"An update on local anaesthetics in dentistry","volume":"68","author":"Haas DA","year":"2002","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.123866"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/19424396.1998.12221721"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.51.515"},{"key":"e_1_2_7_13_2","first-page":"197","article-title":"Onset and duration of articaine and lidocaine on maxillary infiltration","volume":"36","author":"Costa CG","year":"2005","journal-title":"Quintess Int"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.don.0000140576.36513.cb"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.11.009"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.DON.0000125317.21892.8F"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2008.10.020"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.05.002"},{"key":"e_1_2_7_19_2","first-page":"31","article-title":"Cardiac electrophysiological effects of articaine compared with bupivacaine and lidocaine","volume":"84","author":"Moller RA","year":"1994","journal-title":"Oral Health"},{"key":"e_1_2_7_20_2","first-page":"126","article-title":"Comparison of injection pain, heart rate increase, and post injection pain of articaine and lidocaine in a primary intraligamentary injection administered with a computer\u2010controlled local anesthetic delivery system","volume":"51","author":"Nusstein J","year":"2004","journal-title":"Anesth Prog"},{"key":"e_1_2_7_21_2","first-page":"822","article-title":"[Clinical comparative study of local anesthetics. 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