{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:23:07Z","timestamp":1791181387155,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,8,25]],"date-time":"2011-08-25T00:00:00Z","timestamp":1314230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Evidence suggests that frequent and direct exposure to domestic animals has made farmers less susceptible to symptomatic <jats:italic>Escherichia coli<\/jats:italic> O157 infection than other members of the community. We have quantified the seroprevalence of antibodies to <jats:italic>E.\u00a0coli<\/jats:italic> O157 lipopolysaccharide (LPS) from a representative cohort of farm workers in three geographically distinct regions of the United Kingdom during two sampling rounds over a 2\u2010year period. All participants completed a questionnaire to determine the range and extent of recent animal contact alongside other potential occupational and environmental exposure routes. A total of 31\/946 (3.3%) serum samples contained antibodies to <jats:italic>E<\/jats:italic>.\u00a0<jats:italic>coli<\/jats:italic> O157 LPS (from both rounds combined). On the second sampling round, a significant difference in seropositivity was apparent between the three regions, with enhanced seroprevalence linked to recent contact with beef cattle, having a private water supply and contact with a child under 5\u2003years old. Only five seropositive people reported symptoms of a gastrointestinal tract infection, although these symptoms were mild. These results further support the premise of acquired immunity to <jats:italic>E<\/jats:italic>.\u00a0<jats:italic>coli<\/jats:italic> O157 associated with prolonged antigenic exposures within the farming environment.<\/jats:p>","DOI":"10.1111\/j.1863-2378.2011.01430.x","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T01:54:50Z","timestamp":1314842090000},"page":"83-88","source":"Crossref","is-referenced-by-count":7,"title":["Seroprevalence and Risk Factors Associated with <i>Escherichia coli<\/i> O157 in a Farming Population"],"prefix":"10.1111","volume":"59","author":[{"given":"R. S.","family":"Quilliam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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