{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:43:15Z","timestamp":1758634995902,"version":"3.40.3"},"reference-count":16,"publisher":"Wiley","issue":"s2","license":[{"start":{"date-parts":[[2012,9,7]],"date-time":"2012-09-07T00:00:00Z","timestamp":1346976000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Nephropathia epidemica (NE) caused by<jats:italic>Puumala<\/jats:italic>hantavirus (PUUV) is a mild variant of haemorrhagic fever with renal syndrome, which is endemic in Germany. We describe the case of a 67\u2010year\u2010old man initially presenting with acute bilateral angle\u2010closure glaucoma, an atypical clinical presentation of PUUV infection. Subsequently, the patient developed a severe course of disease additionally complicated by profound hepatitis and interstitial nephritis, both phenomena which are rarely described in association with hantavirus infection. Serologic diagnosis was complicated by delayed antibody production until the 10th day of illness; however, PUUV RNA was detectable early in disease. To further analyse this unusual case, sequencing of the PUUV S segment was performed from the patient and regional reservoir host which showed a close relation.<\/jats:p>","DOI":"10.1111\/j.1863-2378.2011.01452.x","type":"journal-article","created":{"date-parts":[[2012,9,7]],"date-time":"2012-09-07T12:04:00Z","timestamp":1347019440000},"page":"110-115","source":"Crossref","is-referenced-by-count":8,"title":["Atypical Severe<i>Puumala<\/i>Hantavirus Infection and Virus Sequence Analysis of the Patient and Regional Reservoir Host"],"prefix":"10.1111","volume":"59","author":[{"given":"I.","family":"Eckerle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Jakob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schmidt\u2010Bacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ettinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Schnitzler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.3201\/eid1309.070552","article-title":"Risk factors for hantavirus infection in Germany, 2005","volume":"13","author":"Abu Sin M.","year":"2007","journal-title":"Emerg. 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