{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:51:58Z","timestamp":1789883518903,"version":"4.0.1"},"reference-count":24,"publisher":"Hindawi Limited","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1153,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1111\/j.1865-1682.2012.01354.x","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T14:48:05Z","timestamp":1341499685000},"page":"351-359","source":"Crossref","is-referenced-by-count":35,"title":["Pathogenicity and Distribution of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in Pigs"],"prefix":"10.1155","volume":"60","author":[{"given":"S. P.","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. G.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z. J.","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. H.","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. J.","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2012,7,5]]},"reference":[{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB101|cit1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3201\/eid1602.090005","article-title":"Origin of highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus, China","volume":"16","author":"An","year":"2010","journal-title":"Emerg. Infect. Dis."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB1|cit2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jviromet.2008.07.006","article-title":"Reverse transcription loop-mediated isothermal amplification for the detection of highly pathogenic porcine reproductive and respiratory syndrome virus","volume":"153","author":"Chen","year":"2008","journal-title":"J. Virol. Methods"},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB2|cit3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1053\/jcpa.1998.0257","article-title":"Distribution of a Korean strain of porcine reproductive and respiratory syndrome virus in experimentally infected pigs, as demonstrated immunohistochemically and by in-situ hybridization","volume":"120","author":"Cheon","year":"1999","journal-title":"Comp Path."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB3|cit4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1177\/104063879700900419","article-title":"Seroprevalence of antibody to porcine reproductive and respiratory syndrome virus using enzyme-linked immunosorbent assay in selected herds in Korea","volume":"9","author":"Cheon","year":"1997a","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB4|cit5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0021-9975(97)80032-1","article-title":"Detection of nucleic acids of porcine reproductive and respiratory syndrome virus in the lungs of naturally infected piglets as determined by in-situ hybridization","volume":"117","author":"Cheon","year":"1997b","journal-title":"J. Comp. Pathol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB5|cit6","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1177\/104063879400600219","article-title":"Development of a streptavidin-biotin immunoperoxidase procedure for the detection of porcine reproductive and respiratory syndrome virus antigen in porcine lung","volume":"6","author":"Halbur","year":"1994","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB6|cit7","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/030098589503200606","article-title":"Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus","volume":"32","author":"Halbur","year":"1995","journal-title":"Vet. Pathol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB7|cit8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1177\/030098589603300205","article-title":"Comparison of the antigen distribution of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus","volume":"33","author":"Halbur","year":"1996","journal-title":"Vet. Pathol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB8|cit9","first-page":"10","article-title":"Highly pathogenic porcine reproductive and respiratory syndrome","volume":"23","author":"Helen","year":"2009","journal-title":"Int. Dis. Monit. Situat. Assess."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB9|cit10","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.tvjl.2007.07.032","article-title":"Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China","volume":"174","author":"Li","year":"2007","journal-title":"Vet J."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB10|cit11","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1128\/CVI.00517-09","article-title":"Dynamic changes in inflammatory cytokines in pigs infected with highly pathogenic porcine reproductive and respiratory syndrome virus","volume":"17","author":"Liu","year":"2010","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB11|cit12","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1128\/JCM.32.9.2197-2203.1994","article-title":"Detection of porcine reproductive and respiratory syndrome virus and efficient differentiation between Canadian and European strains by reverse transcription and PCR amplification","volume":"32","author":"Mardassi","year":"1994","journal-title":"J. Clin. Microbiol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB12|cit13","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1006\/viro.1993.1008","article-title":"Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV","volume":"192","author":"Meulenberg","year":"1993","journal-title":"Virology"},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB13|cit14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/01652176.1991.9694298","article-title":"Pathological, ultrastructural, and immunohistochemical changes caused by Lelystad virus in experimentally induced infections of mystery disease (synonym: porcine epidemic abortion and respiratory syndrome (PEARS))","volume":"13","author":"Pol","year":"1991","journal-title":"Veterinary Quarter."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB14|cit15","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1177\/030098589503200404","article-title":"Pathogenesis of porcine reproductive and respiratory syndrome virus infection in gnotobiotic pigs","volume":"32","author":"Rossow","year":"1995","journal-title":"Vet. Pathol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB15|cit16","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1177\/030098589603300510","article-title":"Chronological immunohistochemical detection and localization of porcine reproductive and respiratory syndrome virus in gnotobiotic pigs","volume":"33","author":"Rossow","year":"1996","journal-title":"Vet. Pathol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB16|cit17","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1099\/0022-1317-79-5-961","article-title":"The molecular biology of arteriviruses","volume":"79","author":"Snijder","year":"1998","journal-title":"J. Gen. Virol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB17|cit18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0378-1135(98)00245-4","article-title":"Influence of pig age on virus titer and bactericidal activity of porcine reproductive and respiratory syndrome virus (PRRSV)-infected pulmonary intravascular macrophages (PIMs)","volume":"63","author":"Thanawongnuwech","year":"1998","journal-title":"Vet. Microbiol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB18|cit19","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1371\/journal.pone.0000526","article-title":"Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark","volume":"2","author":"Tian","year":"2007","journal-title":"PLoS One"},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB19|cit20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.vetmic.2009.03.003","article-title":"An attenuated live vaccine based on highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) protects piglets against HP-PRRS","volume":"138","author":"Tian","year":"2009","journal-title":"Vet. Microbiol."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB20|cit21","first-page":"323","article-title":"Identification and molecular epidemiology of the very virulent porcine reproductive and respiratory syndrome viruses emerged in China","volume":"31","author":"Tong","year":"2007","journal-title":"Chin J Prev Vet Med."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB21|cit22","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1177\/104063879200400203","article-title":"Antigenic comparison of Lelystad virus and swine infertility and respiratory syndrome (SIRS) virus","volume":"4","author":"Wensvoort","year":"1992","journal-title":"J. Vet. Diagn. Invest."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB22|cit23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1743-422X-8-410","article-title":"Generation of an infections clone of HuN4-F112, an attenuated live vaccine strain of porcine reproductive and respiratory syndrome virus","volume":"8","author":"Zhang","year":"2011","journal-title":"Virology Journal."},{"key":"10.1111\/j.1865-1682.2012.01354.x-BIB23|cit24","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1865-1682.2008.01020.x","article-title":"Highly virulent porcine reproductive and respiratory syndrome virus emerged in China","volume":"55","author":"Zhou","year":"2008","journal-title":"Transbound Emerg. Dis."}],"container-title":["Transboundary and Emerging Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1865-1682.2012.01354.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1865-1682.2012.01354.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T15:42:40Z","timestamp":1675957360000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1865-1682.2012.01354.x"}},"subtitle":["Pathogenicity and Distribution of HP-PRRSV"],"short-title":[],"issued":{"date-parts":[[2012,7,5]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1865-1682.2012.01354.x","relation":{},"ISSN":["1865-1674"],"issn-type":[{"value":"1865-1674","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7,5]]}}}