{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:09:52Z","timestamp":1788844192157,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,2,21]],"date-time":"2011-02-21T00:00:00Z","timestamp":1298246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>Congenital hepatic fibrosis (CHF) and bile duct hamartomas (von Meyenburg complexes) are hepatobiliary fibropolycystic diseases. There have been several reports of liver neoplasias arising in hepatobiliary fibropolycystic diseases. However, most of them were cholangiocarcinomas and cases involving hepatocellular carcinoma (HCC) are rare. A 51\u2010year\u2010old woman was found to have multiple hepatic tumors by ultrasonography and enhanced computed tomography (CT) during a regular work\u2010up for the recurrence of lung cancer and thyroid cancer, which had been surgically removed 4 and 3\u2003years ago, respectively. Nodules were observed at S3, S5, and S6 (2\u2003cm in diameter). All of the nodules were hyperattenuated at the early arterial phase, and the main tumor at S5 showed hypoattenuation at the delayed phase on dynamic CT and magnetic resonance imaging (MRI). HCC was suspected from these findings. She also suffered from multiple small cystic lesions in the liver. The surgically removed liver showed HCC arising in CHF, which is a rare histological finding.<\/jats:p>","DOI":"10.1111\/j.1872-034x.2010.00761.x","type":"journal-article","created":{"date-parts":[[2011,2,22]],"date-time":"2011-02-22T01:23:33Z","timestamp":1298337813000},"page":"277-281","source":"Crossref","is-referenced-by-count":5,"title":["Hepatocellular carcinoma occurring in hepatobiliary fibropolycystic disease"],"prefix":"10.1111","volume":"41","author":[{"given":"Hideaki","family":"Kinugasa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiro","family":"Nouso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetuya","family":"Yasunaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Onishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin\u2010ichiro","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenori","family":"Shiraha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Toshimori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kuwaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Hagihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fusao","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinobu","family":"Takaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Kobashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhide","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,21]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840160434"},{"key":"e_1_2_4_3_2","first-page":"477","article-title":"Uber die cystenleber","volume":"64","author":"von\u2010Meyenburg H","year":"1918","journal-title":"Beitr Path Anat"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(86)80073-3"},{"key":"e_1_2_4_5_2","first-page":"113","article-title":"Bile duct carcinoma: a late complication of congenital hepatic fibrosis. Am J","volume":"73","author":"Scott J","year":"1980","journal-title":"Gastroenterology"},{"issue":"4","key":"e_1_2_4_6_2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/annonc\/10.suppl_4.S122","article-title":"Mechanisms of biliary carcinogenesis : a pathogenetic multi\u2010stage cascade towards cholangiocarcinoma","volume":"10","author":"Holzinger F","year":"1999","journal-title":"Ann Oncol"},{"key":"e_1_2_4_7_2","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.5858\/2000-124-1704-COIALW","article-title":"Cholangiocarcinoma occurring in a liver with multiple bile duct hamartomas (von Meyenburg complexes)","volume":"124","author":"Rocken C","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_4_8_2","first-page":"333","article-title":"Cholangiocarcinoma asising from preexisting biliary hamartoma of liver\u2010report of a case","volume":"50","author":"Orii T","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(98)80297-3"},{"key":"e_1_2_4_10_2","first-page":"450","article-title":"Hepatocellular carcinoma arising in congenital hepatic fibrosis","volume":"89","author":"Bauman ME","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2006.12.003"},{"key":"e_1_2_4_12_2","first-page":"1490","article-title":"[A case of hepatocellular carcinoma complicated with Caroli's disease]","volume":"107","author":"Ijima M","year":"2010","journal-title":"Nippon Shokakibyo Gakkai Zasshi"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.24"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2009.066613"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30225"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i8.1321"}],"container-title":["Hepatology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1872-034X.2010.00761.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1872-034X.2010.00761.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T11:35:37Z","timestamp":1697369737000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1872-034X.2010.00761.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,21]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1111\/j.1872-034X.2010.00761.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1872-034x.2010.00761.x","archive":["Portico"],"relation":{},"ISSN":["1386-6346","1872-034X"],"issn-type":[{"value":"1386-6346","type":"print"},{"value":"1872-034X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,21]]}}}