{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T05:09:11Z","timestamp":1755925751183},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,4,7]],"date-time":"2013-04-07T00:00:00Z","timestamp":1365292800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatology Research"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:p>In this report we introduce percutaneous transportal outflow\u2010vessel\u2010occluded sclerotherapy (PTOS) for gastric varices unmanageable by balloon\u2010occluded retrograde transvenous obliteration (BRTO) in two cases and evaluate its safety and efficacy. The PTOS is a technique which could obstruct gastric varices subsequent to the occlusion of the outflow route, being based on the rationale of BRTO. In the PTOS procedure, coil embolization of the outflow vessel is first conducted through a microcatheter advanced beyond the gastric varices via the percutaneous transhepatic approach; sclerosing agent (5% ethanolamine oleate) is then injected into the gastric varices after confirmation of static blood flow in the varices. Two patients underwent initial BRTO that eventually failed because of the presence of numerous fine and abruptly angled outflow vessels (case 1), and the presence of a tortuous and elongated outflow vessel accompanied by numerous small collateral outflows that could not be occluded (case 2). Cases 1 and 2 received PTOS using 5% ethanolamine oleate (15\u2003mL and 10\u2003mL, respectively). Portal venous pressure following PTOS showed an increase from 29 to 34\u2003mmHg in case 1 and remained at 24\u2003mmHg in case 2. No major complication was encountered in either patient. One\u2010year follow\u2010up gastroendoscopy showed no recurrence of gastric varices in either patient. Although PTOS is slightly more invasive than BRTO, PTOS can be used as an alternative catheter treatment procedure for gastric varices that are unmanageable by BRTO.<\/jats:p>","DOI":"10.1111\/j.1872-034x.2012.01078.x","type":"journal-article","created":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T03:46:08Z","timestamp":1365392768000},"page":"430-435","source":"Crossref","is-referenced-by-count":6,"title":["Percutaneous transportal outflow\u2010vessel\u2010occluded sclerotherapy for gastric varices unmanageable by balloon\u2010occluded retrograde transvenous obliteration"],"prefix":"10.1111","volume":"43","author":[{"given":"Nobuyuki","family":"Kawai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Minamiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morio","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ikoma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Sanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouhei","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takami","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoki","family":"Nakai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Sonomura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,7]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.1996.tb00010.x"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.167.5.8911204"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002709900206"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61912-5"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-005-0039-7"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000094615.61428.2e"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000157297.91510.21"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02575474"},{"key":"e_1_2_4_10_2","first-page":"1412","article-title":"Outcome of 100 patients after transjugular intrahepatic portosystemic shunt for variceal hemorrhage","volume":"92","author":"Sahagun G","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-004-0346-4"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000126809.59487.88"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-005-0372-y"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92281-9"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1148\/129.2.327"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.129.2.237"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.146.3.6600846"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.130.1.1"}],"container-title":["Hepatology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1872-034X.2012.01078.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1872-034X.2012.01078.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T21:16:28Z","timestamp":1697318188000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1872-034X.2012.01078.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/j.1872-034X.2012.01078.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1872-034x.2012.01078.x","archive":["Portico"],"relation":{},"ISSN":["1386-6346","1872-034X"],"issn-type":[{"value":"1386-6346","type":"print"},{"value":"1872-034X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}