{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:39:28Z","timestamp":1793813968008,"version":"4.6.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bacterial and parasitic agents are commonly implicated as causes of diarrhea in cats, but there is a paucity of information evaluating epidemiological and prevalence factors associated with most of these organisms in cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Determine the prevalence of selected enteropathogens in diarrheic and nondiarrheic cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>A total of 219 diarrheic and 54 nondiarrheic cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective study. Fresh fecal specimens were submitted for centrifugation flotation, culture, ELISA (Giardia, Cryptosporidium, Clostridium perfringens enterotoxin [CPE], and C. difficile toxin A [TcdA]) and polymerase chain reaction (PCR) testing (Tritrichomonas foetus and Campylobacter spp.). An epidemiologic questionnaire was completed for each cat.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Campylobacter was isolated from significantly fewer diarrheic (21\/219 or 9.6%) versus nondiarrheic cats (15\/54 or 27.8%, P\u00a0= .001), and was detected in 74 of 131 cats (56.5%) via PCR. Campylobacter jejuni, C. helveticus, and C. upsaliensis were detected in 6.8, 100, and 44.6% of the 74 cats. Multiple Campylobacter spp. were identified in 47.3% of these cats. All cats were negative on fecal culture for Salmonella and for C. difficile TcdA via ELISA. CPE was detected in 9\/219 diarrheic (4.1%) and in 1\/54 nondiarrheic cats (1.9%, P\u00a0= .69). Cats &amp;lt; 2\u00a0years were significantly more likely to be infected with intestinal parasites (P\u00a0&amp;lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Routine fecal cultures and toxin immunoassays for detection of bacteria are of limited diagnostic value in diarrheic cats. Molecular-based testing is superior to fecal cultures for detection and identification of Campylobacter spp., but positive test results do not correlate to the presence of disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1939-1676.2011.00843.x","type":"journal-article","created":{"date-parts":[[2011,12,19]],"date-time":"2011-12-19T09:59:20Z","timestamp":1324288760000},"page":"54-60","source":"Crossref","is-referenced-by-count":62,"title":["Prevalence of Selected Bacterial and Parasitic Agents in Feces from Diarrheic and Healthy Control Cats from Northern California"],"prefix":"10.1093","volume":"26","author":[{"given":"E.V.","family":"Queen","sequence":"first","affiliation":[{"name":"Veterinary Medical Teaching Hospital"},{"name":"Loomis Basin Veterinary Clinic , 3901 Sierra College Blvd., P.O. 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