{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:23:33Z","timestamp":1770218613198,"version":"3.49.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Several Bartonella species (spp.) have been identified in dogs diagnosed with infectious endocarditis (IE) or myocarditis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To interrogate cardiac tissues of dogs with suspected IE for the presence of Bartonella spp. DNA of dogs in the Rocky Mountain states.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Nine dogs with a clinical diagnosis of endocarditis from January 1990 to June 2008 were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective study, medical records at the Veterinary Teaching Hospital were searched. Animals were excluded if there was no diagnosis of IE in the original necropsy report. Paraffin embedded tissue blocks and medical records were available from 9 dogs. Total DNA was extracted from the cardiac tissues and assessed for Bartonella spp. DNA by 3 polymerase chain reaction (PCR) methods. For positive samples, the Bartonella spp. were determined by genetic sequencing or fluorogenic real-time PCR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Bartonella henselae DNA was amplified from the tissues of 7 dogs; Bartonella vinsonii subsp berkhoffii DNA was amplified concurrently from 3 dogs. Six dogs were from Colorado and 1 was from Wyoming. Flea or tick infestations were reported in 2 dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Bartonella spp. should be on the differential list for dogs in the Rocky Mountain states. The results emphasize the need for routine use of external parasite control products even in regions perceived to have low risk for flea and tick infestations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1939-1676.2011.0722.x","type":"journal-article","created":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T11:09:18Z","timestamp":1304420958000},"page":"613-616","source":"Crossref","is-referenced-by-count":23,"title":["<i>Bartonella<\/i>\n                    spp. DNA in Cardiac Tissues from Dogs in Colorado and Wyoming"],"prefix":"10.1093","volume":"25","author":[{"given":"A.","family":"Fenimore","sequence":"first","affiliation":[{"name":"Colorado State University Department of Clinical Sciences, , Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Varanat","sequence":"additional","affiliation":[{"name":"North Carolina State University Department of Clinical Sciences, , Raleigh, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Maggi","sequence":"additional","affiliation":[{"name":"North Carolina State University Department of Clinical Sciences, , Raleigh, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Schultheiss","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostic Laboratory, Colorado State University , Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Breitschwerdt","sequence":"additional","affiliation":[{"name":"North Carolina State University Department of Clinical Sciences, , Raleigh, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. R.","family":"Lappin","sequence":"additional","affiliation":[{"name":"Colorado State University Department of Clinical Sciences, , Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,5,1]]},"reference":[{"key":"2026020303442430600_b1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1128\/jcm.33.1.154-160.1995","article-title":"Endocarditis in a dog due to infection with a novel Bartonella subspecies","volume":"33","author":"Breitschwerdt","year":"1995","journal-title":"J Clin Microbiol"},{"key":"2026020303442430600_b2","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.3201\/eid1212.060724","article-title":"Bartonella quintana endocarditis in dogs","volume":"12","author":"Kelly","year":"2006","journal-title":"Emerg Inf Dis"},{"key":"2026020303442430600_b3","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1128\/JCM.39.10.3548-3554.2001","article-title":"Aortic valve endocarditis in a dog due to Bartonella clarridgeiae","volume":"39","author":"Chomel","year":"2001","journal-title":"J Clin Microbiol"},{"key":"2026020303442430600_b4","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.vetmic.2009.08.005","article-title":"Molecular detection of Bartonella henselae and Bartonella koehlerae from aortic valves of Boxer dogs with infective endocarditis","volume":"141","author":"Ohad","year":"2010","journal-title":"Vet Microbiol"},{"key":"2026020303442430600_b5","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1128\/JCM.37.11.3618-3626.1999","article-title":"Bartonella vinsonii subsp. berkhoffii and related members of the alpha subdivision of the Proteobacteria in dogs with cardiac arrhythmias, endocarditis, or myocarditis","volume":"37","author":"Breitschwerdt","year":"1999","journal-title":"J Clin Microbiol"},{"key":"2026020303442430600_b6","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.jfms.2009.12.018","article-title":"Successful treatment of Bartonella henselae endocarditis in a cat","volume":"12","author":"Perez","year":"2010","journal-title":"J Feline Med Surg"},{"key":"2026020303442430600_b7","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1128\/JCM.41.11.5337-5339.2003","article-title":"Fatal case of endocarditis associated with Bartonella henselae type I infection in a domestic cat","volume":"41","author":"Chomel","year":"2003","journal-title":"J Clin Microbiol"},{"key":"2026020303442430600_b8","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1365-3164.2009.00800.x","article-title":"Presence of Bartonella species and Rickettsia species DNA in the blood, oral cavity, skin and claw beds of cats in the United States","volume":"20","author":"Lappin","year":"2009","journal-title":"Vet Derm"},{"key":"2026020303442430600_b9","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1128\/JCM.43.3.1171-1176.2005","article-title":"Potential limitations of the 16S\u201323S rRNA intergenic region for the molecular detection of Bartonella species","volume":"43","author":"Maggi","year":"2005","journal-title":"J Clin Microbiol"},{"key":"2026020303442430600_b10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.mcp.2005.11.002","article-title":"A Bartonella vinsonii berkhoffi i typing scheme based upon 16S\u201323S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates","volume":"20","author":"Maggi","year":"2006","journal-title":"Mol Cell Probes"},{"key":"2026020303442430600_b11","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.3201\/eid1112.050969","article-title":"Bartonella henselae in porpoise blood","volume":"11","author":"Maggi","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"2026020303442430600_b12","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1354\/vp.08-VP-0259-B-BC","article-title":"Cross-contamination in the molecular detection of Bartonella from paraffin-embedded tissues","volume":"46","author":"Varanat","year":"2009","journal-title":"Vet Pathol"},{"key":"2026020303442430600_b13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.mimet.2007.01.010","article-title":"A combined approach for the enhanced detection and isolation of Bartonella species in dog blood samples: Pre-enrichment liquid culture followed by PCR and subculture onto agar plates","volume":"69","author":"Duncan","year":"2007","journal-title":"J Microbiol Methods"}],"container-title":["Journal of Veterinary Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1939-1676.2011.0722.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/25\/3\/613\/66682025\/j.1939-1676.2011.0722.x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/25\/3\/613\/66682025\/j.1939-1676.2011.0722.x.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T08:44:59Z","timestamp":1770108299000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jvim\/article\/25\/3\/613\/8451289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,1]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,5,1]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1939-1676.2011.0722.x","relation":{},"ISSN":["1939-1676"],"issn-type":[{"value":"1939-1676","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2011,5]]},"published":{"date-parts":[[2011,5,1]]}}}