{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:04:50Z","timestamp":1791266690662,"version":"4.1.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Familial hypertrophic cardiomyopathy (HCM) has been described previously in British Shorthair cats (BSH), but until now, no reports have been published describing the prevalence of the disease within this breed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study was to assess the prevalence of HCM in a large cohort of BSH and to evaluate the effect of sex, weight, and increasing age as potential risk factors for this disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Three hundred and twenty-nine BSH presented for routine HCM screening during a 4-year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective cross-sectional study in which all cats were screened for HCM by conventional echocardiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 329 cats were examined, 214 females and 115 males, with a median age of 2.3 years (range, 0.8\u201314.1). Twenty-eight cats (8.5%) were classified as HCM-positive, 14 (4.3%) as equivocal, 282 (85.7%) as HCM-negative, and 5 (2.1%) were diagnosed with other cardiac diseases. The median age for diagnosis of HCM was 2.7 years (range, 0.9\u201314.1). Male cats had a significantly higher occurrence of HCM (20.4%) compared with the females (2.1%) corresponding to an odds ratio of 7.89 (95 % CI, 2.54\u201328.08) for males versus females adjusted for age and weight (P &amp;lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The BSH in our cohort had a high prevalence of HCM, often of early onset and with a significant male sex predisposition. We strongly recommend echocardiographic screening in this breed, especially cats used for breeding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1939-1676.2011.0751.x","type":"journal-article","created":{"date-parts":[[2011,7,7]],"date-time":"2011-07-07T16:01:25Z","timestamp":1310054485000},"page":"866-871","source":"Crossref","is-referenced-by-count":51,"title":["Prevalence of Hypertrophic Cardiomyopathy in a Cohort of British Shorthair Cats in Denmark"],"prefix":"10.1093","volume":"25","author":[{"given":"S.","family":"Granstr\u00f6m","sequence":"first","affiliation":[{"name":"University of Copenhagen Department of Small Animal Clinical Sciences, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.T.","family":"Nyberg Godiksen","sequence":"additional","affiliation":[{"name":"Statens Serum Institut Department of Clinical Biochemistry and Immunology, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Statens Serum Institut Department of Clinical Biochemistry and Immunology, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.B.","family":"Pipper","sequence":"additional","affiliation":[{"name":"University of Copenhagen the Department of Basic Sciences and Environment, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.T.","family":"Willesen","sequence":"additional","affiliation":[{"name":"University of Copenhagen Department of Small Animal Clinical Sciences, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Koch","sequence":"additional","affiliation":[{"name":"University of Copenhagen Department of Small Animal Clinical Sciences, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,7,1]]},"reference":[{"key":"2026020303470654500_b1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1024\/0036-7281.149.2.65","article-title":"Prevalence of heart disease in symptomatic cats: An overview from 1998 to 2005","volume":"149","author":"Riesen","year":"2007","journal-title":"Schweiz Arch Tierheilkd"},{"key":"2026020303470654500_b2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1098-612X(02)00133-X","article-title":"Feline idiopathic cardiomyopathy: A retrospective study of 106 cats (1994\u20132001)","volume":"5","author":"Ferasin","year":"2003","journal-title":"J Feline Med Surg"},{"key":"2026020303470654500_b3","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1161\/01.CIR.92.9.2645","article-title":"Echocardiographic assessment of spontaneously occurring feline hypertrophic cardiomyopathy. 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