{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:05:55Z","timestamp":1791266755956,"version":"4.1.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"DESV residency program of Vetoquinol"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary hypertrophic cardiomyopathy (HCM) is the most common feline heart disease and has been demonstrated to be inherited in some breeds. However, few studies have compared HCM phenotypes and survival according to breed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare epidemiological characteristics, clinical findings, left ventricular (LV) geometric patterns, and survival in several breeds of cats with HCM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Three hundred and forty-four cats from 5 different breeds (Persian, Domestic Shorthair [DS], Sphynx, Maine coon [MC], and Chartreux) with primary HCM diagnosed by conventional echocardiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study. Cats were classified according to breed and clinical status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Age at the time of diagnosis was lower (P\u00a0&amp;lt;\u00a0.001) in MC (median age, 2.5\u00a0years) and Sphynx (3.5\u00a0years) than in other breeds (OB), ie, 8.0, 8.0, and 11.0\u00a0years for DS, Chartreux, and Persians, respectively. The prevalence of LV outflow tract obstruction was higher (P\u00a0&amp;lt;\u00a0.001) in Persians (23\/41; 56%) than in OB (115\/303; 38%). Age at the first cardiac event was lower (P\u00a0&amp;lt;\u00a0.01) in MC (median age, 2.5\u00a0years) than in OB (7.0\u00a0years). All cats surviving &amp;gt;\u00a015\u00a0years of age were DS, Persians, or Chartreux. Sudden death (representing 24% of all cardiac deaths) was observed only in 3 breeds (DS, MC, and Sphynx).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Importance<\/jats:title>\n                    <jats:p>As in humans, feline HCM is characterized by marked phenotypic variability with several breed-dependent features regarding epidemiology, LV geometric patterns, and clinical course (ie, age at diagnosis, 1st cardiac event, and cause of death).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1939-1676.2012.00906.x","type":"journal-article","created":{"date-parts":[[2012,3,24]],"date-time":"2012-03-24T04:53:05Z","timestamp":1332564785000},"page":"532-541","source":"Crossref","is-referenced-by-count":73,"title":["Comparative Echocardiographic and Clinical Features of Hypertrophic Cardiomyopathy in 5 Breeds of Cats: A Retrospective Analysis of 344 Cases (2001\u20132011)"],"prefix":"10.1093","volume":"26","author":[{"given":"E.","family":"Trehiou-Sechi","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris-Est, Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de Cardiologie d'Alfort (UCA), Centre Hospitalier Universitaire V\u00e9t\u00e9rinaire d'Alfort (CHUVA), 7 avenue du g\u00e9n\u00e9ral de Gaulle , 94704 Maisons-Alfort cedex,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Tissier","sequence":"additional","affiliation":[{"name":"INSERM, U955, Equipe 03, 51 avenue du Mar\u00e9chal de Lattre de Tassigny , 94010 Cr\u00e9teil cedex,","place":["France"]},{"name":"Universit\u00e9 Paris-Est, Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de Pharmacie-Toxicologie , 7 avenue du g\u00e9n\u00e9ral de Gaulle 94704 Maisons-Alfort cedex,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Gouni","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Est, Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de Cardiologie d'Alfort (UCA), Centre Hospitalier Universitaire V\u00e9t\u00e9rinaire d'Alfort (CHUVA), 7 avenue du g\u00e9n\u00e9ral de Gaulle , 94704 Maisons-Alfort cedex,","place":["France"]},{"name":"INSERM, U955, Equipe 03, 51 avenue du Mar\u00e9chal de Lattre de Tassigny , 94010 Cr\u00e9teil cedex,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Misbach","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Est, Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de Cardiologie d'Alfort (UCA), Centre Hospitalier Universitaire V\u00e9t\u00e9rinaire d'Alfort (CHUVA), 7 avenue du g\u00e9n\u00e9ral de Gaulle , 94704 Maisons-Alfort 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