{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T13:45:33Z","timestamp":1775742333284,"version":"3.50.1"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To report the clinical presentation, imaging characteristics, treatment results, and histopathological findings of a previously undescribed vertebral malformation in the Basset Hound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals and Methods<\/jats:title>\n                    <jats:p>Retrospective case series study. Eighteen Basset Hounds presented for evaluation of a suspected cervical spinal cord problem. All dogs underwent computed tomography myelography or magnetic resonance imaging of the cervical region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen male and 5 female Basset Hounds between 6\u00a0months and 10.8\u00a0years of age (median: 1.4\u00a0years) were studied. Clinical signs varied from cervical hyperesthesia to nonambulatory tetraparesis. Imaging demonstrated a well-defined and smooth hypertrophy of the dorsal lamina and spinous process of \u22652 adjacent vertebrae. Although this bony abnormality could decrease the ventrodorsal vertebral canal diameter, dorsal midline spinal cord compression was predominantly caused by ligamentum flavum hypertrophy. The articulation between C4 and C5 was most commonly affected. Three dogs were lost to follow-up, 10 dogs underwent dorsal laminectomy, and medical management was initiated in 5 dogs. Surgery resulted in a good outcome with short hospitalization times (median: 4.5\u00a0days) in all dogs, whereas medical management produced more variable results. Histopathology confirmed ligamentum flavum hypertrophy and demonstrated the fibrocartilaginous nature of this anomaly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Dorsal lamina and spinous process hypertrophy leading to ligamentum flavum hypertrophy should be included in the differential diagnosis of Basset Hounds with cervical hyperesthesia or myelopathy. Prognosis after decompressive surgery is favorable. Although a genetic component is suspected, additional studies are needed to determine the specific etiology of this disorder.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1939-1676.2012.00990.x","type":"journal-article","created":{"date-parts":[[2012,9,15]],"date-time":"2012-09-15T00:51:55Z","timestamp":1347670315000},"page":"1374-1382","source":"Crossref","is-referenced-by-count":8,"title":["Cervical Vertebral Stenosis Associated with a Vertebral Arch Anomaly in the Basset Hound"],"prefix":"10.1093","volume":"26","author":[{"given":"S.","family":"De Decker","sequence":"first","affiliation":[{"name":"Royal Veterinary College, University of London Department of Veterinary Clinical Sciences, , Hawkshed Lane, North Mymms, Hatfield, Hertfordshire,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"De Risio","sequence":"additional","affiliation":[{"name":"Centre for Small Animal Studies, Animal Health Trust , Lanwades Park, Kentford, Newmarket, Suffolk,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lowrie","sequence":"additional","affiliation":[{"name":"Davies Veterinary Specialists , Manor Farm Business Park, Higham Gobion, Higham Gobion, Hertfordshire,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Mauler","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Ghent University Department of Small Animal Medicine and Clinical Biology, , Merelbeke,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Beltran","sequence":"additional","affiliation":[{"name":"Centre for Small Animal Studies, Animal Health Trust , Lanwades Park, Kentford, Newmarket, Suffolk,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Giedja","sequence":"additional","affiliation":[{"name":"Royal Veterinary College, University of London Department of Veterinary Basic Sciences, , London,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.J.","family":"Kenny","sequence":"additional","affiliation":[{"name":"Royal Veterinary College, University of London Department of Veterinary Clinical Sciences, , Hawkshed Lane, North Mymms, Hatfield, Hertfordshire,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Gielen","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Ghent University Department of Medical Imaging of Domestic Animals and Orthopedics of Small Animals, , Merelbeke,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Garosi","sequence":"additional","affiliation":[{"name":"Davies Veterinary Specialists , Manor Farm Business Park, Higham Gobion, Higham Gobion, Hertfordshire,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Volk","sequence":"additional","affiliation":[{"name":"Royal Veterinary College, University of London Department of Veterinary Clinical Sciences, , Hawkshed Lane, North Mymms, Hatfield, Hertfordshire,","place":["England"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2012,11,1]]},"reference":[{"key":"2026020600173718800_jvim990-bib-0001","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.cvsm.2010.06.002","article-title":"Differential diagnosis of spinal diseases","volume":"40","author":"Da Costa","year":"2010","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"2026020600173718800_jvim990-bib-0002","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.cvsm.2010.05.009","article-title":"Congenital spinal malformations in small animals","volume":"40","author":"Westworth","year":"2010","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"2026020600173718800_jvim990-bib-0003","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1038\/ng.2007.4","article-title":"Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs","volume":"19","author":"Salmon Hillbertz","year":"2007","journal-title":"Nat Genet"},{"issue":"6","key":"2026020600173718800_jvim990-bib-0004","first-page":"1","article-title":"Spinal dysraphism in the dog. 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