{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:52:28Z","timestamp":1790059948663,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T00:00:00Z","timestamp":1315440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Oral Microbiology"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Porphyromonas gingivalis<\/jats:italic>\n                    is a primary pathogen involved in the initiation and progression of adult chronic periodontitis. Its colonization on oral surfaces is a necessary first step leading to infection. FimA, a subunit protein of major (long) fimbriae, is a well\u2010known virulence factor. Based on its nucleotide sequence, FimA is classified into several genotypes. We compared here the transcriptional levels of the\n                    <jats:italic>fimA<\/jats:italic>\n                    gene in several\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    strains using real\u2010time polymerase chain reaction analysis, fimbrial display on the\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    surface using transmission electronic microscopy, and the adherence competencies of\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    strains carrying different types of FimAs towards saliva and\n                    <jats:italic>Streptococcus gordonii<\/jats:italic>\n                    surfaces using mutagenesis analysis. We demonstrated differential expression of each\n                    <jats:italic>fimA<\/jats:italic>\n                    gene in these\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    strains. A correlation of the transcription level of\n                    <jats:italic>fimA<\/jats:italic>\n                    and binding activity of\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    was revealed. We show that\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    strains with genotype I and II of FimA are efficient in interaction with saliva or\n                    <jats:italic>S.\u00a0gordonii<\/jats:italic>\n                    . This work highlights the important role of FimA type I and II in\n                    <jats:italic>P.\u00a0gingivalis<\/jats:italic>\n                    attachment to oral surfaces.\n                  <\/jats:p>","DOI":"10.1111\/j.2041-1014.2011.00626.x","type":"journal-article","created":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T08:46:08Z","timestamp":1315471568000},"page":"388-395","source":"Crossref","is-referenced-by-count":33,"title":["Differential expression and adherence of\n                    <i>Porphyromonas gingivalis<\/i>\n                    FimA genotypes"],"prefix":"10.1111","volume":"26","author":[{"given":"C.","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.5.1426-1430.1999"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2003.00065.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00366-08"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.10.1661"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1993.2467"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.62.5.1696-1704.1994"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2006.00825.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2009.00511.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00797-06"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2005.00779.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2002.01637.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2007.00406.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2004.04291.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.00797.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.00797.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2009.00519.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1097(04)00064-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2005.00107.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01411.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2006.00312.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2009.00545.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2008.01116.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2007.00975.x"}],"container-title":["Molecular Oral Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.2041-1014.2011.00626.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.2041-1014.2011.00626.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T04:05:27Z","timestamp":1697256327000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.2041-1014.2011.00626.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,8]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1111\/j.2041-1014.2011.00626.x"],"URL":"https:\/\/doi.org\/10.1111\/j.2041-1014.2011.00626.x","archive":["Portico"],"relation":{},"ISSN":["2041-1006","2041-1014"],"issn-type":[{"value":"2041-1006","type":"print"},{"value":"2041-1014","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,8]]}}}