{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:14:21Z","timestamp":1697444061112},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T00:00:00Z","timestamp":1316044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest & Clin Dent"],"published-print":{"date-parts":[[2012,8]]},"abstract":"Abstract<\/jats:bold> Aim:\u2002<\/jats:bold> Previous work has indicated that environmental stresses on bacteria might lead to an upregulation of stress response. LED curing lights (315\u2013400\u2003nm) and other UV lights used in tooth whitening cosmetic procedures might act as stresses. We examined the effect of UV\u2010C light, as a high\u2010energy surrogate to the lower\u2010energy UV\u2010A light used in such instruments, to examine its effect on the antibiotic susceptibility of viridans group streptococci.<\/jats:p>Methods:\u2002<\/jats:bold> Twelve species of viridans group streptococci were examined in this study: Streptococcus anginosus<\/jats:italic>, Streptococcus australis<\/jats:italic>, Streptococcus cristatus<\/jats:italic>, Streptococcus gordonii<\/jats:italic>, Streptococcus infantis<\/jats:italic>, Streptococcus mitis<\/jats:italic>, Streptococcus mutans<\/jats:italic>, Streptococcus oralis<\/jats:italic>, Streptococcus parasanguinis<\/jats:italic>, Streptococcus pneumoniae<\/jats:italic>, Streptococcus salivarius<\/jats:italic>, and Streptococcus sanguinis.<\/jats:italic> These organisms were exposed to varying degrees of sublethal UV\u2010C radiation, and their minimum inhibitory concentration susceptibility was determined by broth dilution assay against three classes of commonly\u2010used antibiotics: \u03b2\u2010lactams (penicillin), macrolides (erythromycin), and fluoroquinolones (ciprofloxacin).<\/jats:p>Results:\u2002<\/jats:bold> There was no significant difference between antibiotic susceptibility before UV\u2010C exposure and following maximum sublethal stress, prior to cell death due to fatal UV\u2010C exposure.<\/jats:p>Conclusions:\u2002<\/jats:bold> Exposure to UV\u2010C light will not result in altered antibiotic susceptibility patterns on viridans group streptococci. Given that UV\u2010C is more toxic and mutagenic than UV\u2010A light, it is unlikely than UV\u2010A light would yield any difference in response to such exposure.<\/jats:p>","DOI":"10.1111\/j.2041-1626.2011.00100.x","type":"journal-article","created":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T09:22:27Z","timestamp":1316164947000},"page":"198-202","source":"Crossref","is-referenced-by-count":1,"title":["UV\u2010C\u2010irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to \u03b2\u2010lactam, macrolide, and fluoroquinolone antibiotic agents"],"prefix":"10.1111","volume":"3","author":[{"given":"Yasunori","family":"Maeda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson A.","family":"Coulter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin E.","family":"Goldsmith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Cherie Millar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00578-06"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.15.4669-4672.1999"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2004.02401.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-2244(99)00060-6"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1159572"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp213"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2008.07.006"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1039\/b813132e"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.16.2.189-208.2003"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2010.03.004"},{"key":"e_1_2_6_12_2","volume-title":"Performance standards for antimicrobial susceptibility testing","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2005"}],"container-title":["Journal of Investigative and Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.2041-1626.2011.00100.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.2041-1626.2011.00100.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T02:04:43Z","timestamp":1697335483000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.2041-1626.2011.00100.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,15]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1111\/j.2041-1626.2011.00100.x"],"URL":"https:\/\/doi.org\/10.1111\/j.2041-1626.2011.00100.x","archive":["Portico"],"relation":{},"ISSN":["2041-1618","2041-1626"],"issn-type":[{"value":"2041-1618","type":"print"},{"value":"2041-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,15]]}}}