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Latex allergy, dental caries, difficulty in mouth opening, and sitting in a dental chair are common problems. There is a high risk of anaphylactic response during anaesthesia. There could be associated craniosynostosis causing maxillary deficiency, and malformed sella turcica might be seen. An association of the defects has been linked with orofacial clefts and Down syndrome.<\/jats:p>","DOI":"10.1111\/j.2041-1626.2012.00141.x","type":"journal-article","created":{"date-parts":[[2012,12,18]],"date-time":"2012-12-18T19:09:49Z","timestamp":1355857789000},"page":"3-8","source":"Crossref","is-referenced-by-count":7,"title":["Neural tube defects and their significance in clinical dentistry: a mini review"],"prefix":"10.1111","volume":"4","author":[{"given":"Anuradha","family":"Garg","sequence":"first","affiliation":[{"name":"Unit of Orthodontics Oral Health Sciences Centre Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Utreja","sequence":"additional","affiliation":[{"name":"Unit of Orthodontics Oral Health Sciences Centre Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satinder P.","family":"Singh","sequence":"additional","affiliation":[{"name":"Unit of Orthodontics Oral Health Sciences Centre Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh K.","family":"Angurana","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.44.s3.2.x"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30049"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/10454411000110030201"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/302310"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-4520.2006.00104.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199305000-00002"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30056"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.44.s3.3.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03720040050026"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67319-9"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38336.664352.82"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911113412001"},{"key":"e_1_2_12_14_1","volume-title":"Report of the birth defects registry of Western Australia 1980\u20102009","author":"Bower C","year":"2010"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30057"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.10982"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ddrr.88"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-010-1368-7"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420170113"},{"key":"e_1_2_12_20_1","first-page":"246","article-title":"Antibiotic prophylaxis for patients with hydrocephalus shunts: a survey of pediatric dentistry and neurosurgery program directors","volume":"14","author":"Acs G","year":"1992","journal-title":"Pediatr Dent"},{"key":"e_1_2_12_21_1","first-page":"57","article-title":"Spina bifida","volume":"64","author":"Deshmukh SS","year":"1997","journal-title":"Indian J Pediatr"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70359-2"},{"key":"e_1_2_12_23_1","first-page":"643","volume-title":"Children with disabilities","author":"Helpin ML","year":"1977"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2092(06)61118-6"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(96)00213-3"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513819609168714"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/20.4.443"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2005.04.003"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13080-2"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.11.1637"},{"key":"e_1_2_12_31_1","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1001\/jama.1980.03310240023017","article-title":"Prenatal detection of neural tube defects. 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