{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:12:59Z","timestamp":1758636779249},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T00:00:00Z","timestamp":1214611200000},"content-version":"vor","delay-in-days":2919,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2000,7]]},"abstract":"<jats:p>PROBLEM: Although leukocytes do not possess significant numbers of ovarian steroid hormone receptors, their numbers in the endometrium vary consistently, relative to the menstrual cycle. The possibility that cell types within the endometrium express leukocyte\u2010attracting genes in response to ovarian hormones was investigated.\u2028 METHOD OF STUDY: Endometrial biopsies were collected 10 days post\u2010leutinizing hormone surge; the cell types were separated and cultured individually for 5 days in the presence of increasing amounts of estrogen or progesterone. Following culture, RNA was collected from cells and reverse\u2010transcription\u2010polymerase chain reaction was used to determine relative levels of gene expression of monocyte chemotactic proteins (MCP)\u20101, \u20102, and \u20103, and interleukin (IL)\u201012p35 and p40.\u2028 RESULTS: Although both endometrial stroma and glands were able to make MCP mRNA, steady\u2010state levels of gene expression did not vary significantly relative to hormone treatment. The same was found for the p35 molecule of the <jats:italic>IL\u201012<\/jats:italic> gene; however, differences were observed for the p40 subunit.\u2028 CONCLUSIONS: Within the human endometrium, chemokines other than MCP and IL\u201012 are most likely responsible for cycle\u2010related leukocyte recruitment.<\/jats:p>","DOI":"10.1111\/j.8755-8920.2000.440103.x","type":"journal-article","created":{"date-parts":[[2003,12,17]],"date-time":"2003-12-17T11:57:18Z","timestamp":1071662238000},"page":"16-21","source":"Crossref","is-referenced-by-count":6,"title":["Stimulation of Uterine Cell Cytokine Production By Ovarian Hormones"],"prefix":"10.1111","volume":"44","author":[{"given":"J.A.","family":"DELOIA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"STEWART\u2010AKERS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"BREKOSKY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"KUBIK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"STEWART\u2010AKERS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,6,28]]},"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.8755-8920.2000.440103.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.8755-8920.2000.440103.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.8755-8920.2000.440103.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T06:40:50Z","timestamp":1698561650000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.8755-8920.2000.440103.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["10.1111\/j.8755-8920.2000.440103.x"],"URL":"https:\/\/doi.org\/10.1111\/j.8755-8920.2000.440103.x","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}