{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:09:58Z","timestamp":1791317398564,"version":"4.3.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2017,3,12]],"date-time":"2017-03-12T00:00:00Z","timestamp":1489276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2017,3,12]],"date-time":"2017-03-12T00:00:00Z","timestamp":1489276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Appl Microbiol"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1111\/jam.13400","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T02:10:40Z","timestamp":1483927840000},"page":"911-920","source":"Crossref","is-referenced-by-count":155,"title":["Artepillin C and phenolic compounds responsible for antimicrobial and antioxidant activity of green propolis and\n                    <i>Baccharis dracunculifolia<\/i>\n                    DC"],"prefix":"10.1093","volume":"122","author":[{"given":"R.S.","family":"Veiga","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3383-9422","authenticated-orcid":false,"given":"S.","family":"De Mendon\u00e7a","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.B.","family":"Mendes","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Paulino","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Mimica","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas da Santa Casa de S\u00e3o Paulo; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.A.","family":"Lagareiro Netto","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.S.","family":"Lira","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.G.-C.","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Plant Biology and Pharmacy Course; Institute of Biology; University of Campinas; UNICAMP; Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Negr\u00e3o","sequence":"additional","affiliation":[{"name":"Apis Brasil - Green Eucalypt Propolis Ltd; Pindamonhangaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.C.","family":"Marcucci","sequence":"additional","affiliation":[{"name":"Universidade Anhanguera; P\u00f3s-Gradua\u00e7\u00e3o em Farm\u00e1cia; S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,3,12]]},"reference":[{"key":"10.1111\/jam.13400-BIB0001|jam13400-cit-0001","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1271\/bbb.58.945","article-title":"Isolation and identification of antimicrobial compounds in Brazilian propolis","volume":"58","author":"Aga","year":"1994","journal-title":"Biosci Biotechnol Biochem"},{"key":"10.1111\/jam.13400-BIB0002|jam13400-cit-0002","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.3390\/12071496","article-title":"Comparative evaluation of various total antioxidant capacity assays applied to phenolic compounds with the CUPRAC assay","volume":"12","author":"Apak","year":"2007","journal-title":"Molecules"},{"key":"10.1111\/jam.13400-BIB0003|jam13400-cit-0003","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s12161-008-9067-7","article-title":"Review of methods to determine antioxidant capacities","volume":"2","author":"Ayse","year":"2009","journal-title":"Food Anal Methods"},{"key":"10.1111\/jam.13400-BIB0004|jam13400-cit-0004","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00203-002-0436-0","article-title":"Factors influencing methicillin resistance in Staphylococci","volume":"178","author":"B\u00e4chi","year":"2002","journal-title":"Arch Microbiol"},{"key":"10.1111\/jam.13400-BIB0005|jam13400-cit-0005","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/ecam\/neh059","article-title":"Recent trends and important developments in propolis research","volume":"2","author":"Bankova","year":"2005","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1111\/jam.13400-BIB0006|jam13400-cit-0006","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1051\/apido:2000102","article-title":"Propolis: recent advances in chemistry and plant origin","volume":"31","author":"Bankova","year":"2000","journal-title":"Apidology"},{"key":"10.1111\/jam.13400-BIB0007|jam13400-cit-0007","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1078\/0944-7113-00004","article-title":"Hepatoprotective and anti Helicobater pylori activities of constituents from Brazilian propolis","volume":"8","author":"Banskota","year":"2001","journal-title":"Phytomedicine"},{"key":"10.1111\/jam.13400-BIB0008|jam13400-cit-0008","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1515\/znc-1997-11-1217","article-title":"Potent free radical scavenging activity of Propol isolated from Brazilian propolis","volume":"52","author":"Basnet","year":"1997","journal-title":"Z Naturforsch"},{"key":"10.1111\/jam.13400-BIB0009|jam13400-cit-0009","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0023-6438(95)80008-5","article-title":"Use of a free radical method to evaluate antioxidant activity","volume":"28","author":"Brand-Williams","year":"1995","journal-title":"LWT-Food Sci Technol"},{"key":"10.1111\/jam.13400-BIB0010|jam13400-cit-0010","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0031-9422(00)90664-2","article-title":"Phenylpropanoids and other secondary metabolites from Baccharis linnearis","volume":"35","author":"Brown","year":"1994","journal-title":"Phytochemistry"},{"key":"10.1111\/jam.13400-BIB0011|jam13400-cit-0011","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0278-6915(97)00145-2","article-title":"Review of the biological properties and toxicity of bee propolis (Propolis)","volume":"36","author":"Burdock","year":"1998","journal-title":"Food Chem Toxicol"},{"key":"10.1111\/jam.13400-BIB0012|jam13400-cit-0012","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0924-8579(07)72175-1","article-title":"Staphylococci","volume":"29","author":"Casey","year":"2007","journal-title":"Int J Antimicrob Agents"},{"key":"10.1111\/jam.13400-BIB0013|jam13400-cit-0013","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1590\/S0100-40422007000700003","article-title":"Pr\u00f3polis do sudeste e nordeste do Brasil: influ\u00eancia da sazonalidade na atividade antibacteriana e composi\u00e7\u00e3o fen\u00f3lica","volume":"30","author":"Castro","year":"2007","journal-title":"Quim Nova"},{"key":"10.1111\/jam.13400-BIB0014|jam13400-cit-0014","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1086\/502522","article-title":"The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges","volume":"26","author":"Cosgrove","year":"2005","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1111\/jam.13400-BIB0015|jam13400-cit-0015","doi-asserted-by":"crossref","first-page":"73D80","DOI":"10.1016\/S0378-8741(03)00259-9","article-title":"Constituents of the Argentinian medicinal plant Baccharis grisebachii and their antimicrobial activity","volume":"89","author":"Feresin","year":"2003","journal-title":"J Ethnopharmacol"},{"key":"10.1111\/jam.13400-BIB0016|jam13400-cit-0016","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/0005772X.1979.11097738","article-title":"Propolis: a review","volume":"60","author":"Ghisalberti","year":"1979","journal-title":"Bee World"},{"key":"10.1111\/jam.13400-BIB0017|jam13400-cit-0017","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1086\/533591","article-title":"Pathogenesis of methicillin-resistant Staphylococcus aureus infection","volume":"46","author":"Gordon","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1111\/jam.13400-BIB0018|jam13400-cit-0018","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.fct.2011.11.014","article-title":"Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage","volume":"50","author":"Guimar\u00e3es","year":"2012","journal-title":"Food and Chem Toxicol"},{"key":"10.1111\/jam.13400-BIB0019|jam13400-cit-0019","doi-asserted-by":"crossref","first-page":"572D584","DOI":"10.1016\/S0955-2863(02)00208-5","article-title":"Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships","volume":"13","author":"Heim","year":"2002","journal-title":"J Nutr Biochem"},{"key":"10.1111\/jam.13400-BIB0020|jam13400-cit-0020","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ijid.2010.05.003","article-title":"Methicillin-resistant Staphylococcus aureus: the superbug","volume":"14","author":"Ippolito","year":"2010","journal-title":"Int J Infect Dis"},{"key":"10.1111\/jam.13400-BIB0021|jam13400-cit-0021","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1021\/np010211x","article-title":"Anti-AIDS agents. 48. Anti-HIV activity of moronic acid derivatives and the new mellifore-related triterpenoid isolated from Brazilian propolis","volume":"64","author":"Ito","year":"2001","journal-title":"J Nat Prod"},{"key":"10.1111\/jam.13400-BIB0022|jam13400-cit-0022","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1248\/bpb.32.1947","article-title":"1,1-Diphenyl-2-picrylhydrazyl radical scavenging activity of bee products and their constituents determined by ESR","volume":"32","author":"Izuta","year":"2009","journal-title":"Biol Pharm Bull"},{"key":"10.1111\/jam.13400-BIB0023|jam13400-cit-0023","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1046\/j.1525-1500.1998.00020.x","article-title":"Apoptosis and suppression of tumor growth by artepillin C extracted from Brazilian propolis","volume":"22","author":"Kimoto","year":"1998","journal-title":"Cancer Detect Prev"},{"key":"10.1111\/jam.13400-BIB0024|jam13400-cit-0024","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1021\/np50045a025","article-title":"Secondary metabolites from Chilean Baccharis species","volume":"49","author":"Labbe","year":"1986","journal-title":"J Nat Prod"},{"key":"10.1111\/jam.13400-BIB0025|jam13400-cit-0025","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1211\/jpp.59.4.0017","article-title":"Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity","volume":"59","author":"Lemos","year":"2007","journal-title":"J Pharm Pharmacol"},{"key":"10.1111\/jam.13400-BIB0026|jam13400-cit-0026","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1203\/PDR.0b013e31819dc44d","article-title":"Molecular pathogenesis of Staphylococcus aureus infection","volume":"65","author":"Liu","year":"2009","journal-title":"Pediatric Res"},{"key":"10.1111\/jam.13400-BIB0027|jam13400-cit-0027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0145954","article-title":"Chemical composition and biological activity of extracts obtained by supercritical extraction and ethanolic extraction of brown, green and red propolis derived from different geographic regions in Brazil","volume":"11","author":"Machado","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1111\/jam.13400-BIB0028|jam13400-cit-0028","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0378-8741(00)00326-3","article-title":"Phenolic compounds from Brazilian propolis with pharmacological activities","volume":"74","author":"Marcucci","year":"2001","journal-title":"J Ethnopharmacol"},{"key":"10.1111\/jam.13400-BIB0029|jam13400-cit-0029","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1515\/znc-1997-9-1020","article-title":"Isolation and characterization of cytotoxic diterpenoid isomers from propolis","volume":"52","author":"Matsuno","year":"1997","journal-title":"Z Naturforsch"},{"key":"10.1111\/jam.13400-BIB0030|jam13400-cit-0030","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/ptr.2658","article-title":"Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice","volume":"23","author":"Messerli","year":"2009","journal-title":"Phytother Res"},{"key":"10.1111\/jam.13400-BIB0031|jam13400-cit-0031","doi-asserted-by":"crossref","first-page":"12D17","DOI":"10.1016\/S0003-9861(03)00284-4","article-title":"Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism","volume":"417","author":"Murota","year":"2003","journal-title":"Arch Biochem Biophys"},{"key":"10.1111\/jam.13400-BIB0032|jam13400-cit-0032","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/ptr.5510","article-title":"Artepillin C and other herbal PAK1-blockers: effects on hair cell proliferation and related PAK1-dependent biological function in cell culture","volume":"30","author":"Nguyen","year":"2016","journal-title":"Phytother Res"},{"key":"10.1111\/jam.13400-BIB0033|jam13400-cit-0033","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/j.1365-2621.2003.tb05699.x","article-title":"Effects of light, oxygen, and pH on the absorbance of 2,2-diphenyl-1-picrylhydrazyl","volume":"68","author":"Ozcelik","year":"2003","journal-title":"J Food Sci"},{"key":"10.1111\/jam.13400-BIB0034|jam13400-cit-0034","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s002849900274","article-title":"Antimicrobial activity of propolis on oral microorganisms","volume":"36","author":"Park","year":"1998","journal-title":"Curr Microbiol"},{"key":"10.1111\/jam.13400-BIB0035|jam13400-cit-0035","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1021\/jf021060m","article-title":"Chemical constituents in Baccharis dracunculifolia as the main botanical origin of Southeastern Brazilian propolis","volume":"52","author":"Park","year":"2004","journal-title":"J Agric Food Chem"},{"key":"10.1111\/jam.13400-BIB0037|jam13400-cit-0037","doi-asserted-by":"crossref","first-page":"9257","DOI":"10.3390\/molecules19079257","article-title":"Protective effects of Baccharis dracunculifolia leaves extract against carbon tetrachloride- and acetaminophen-induced hepatotoxicity in experimental animals","volume":"19","author":"Rezende","year":"2014","journal-title":"Molecules"},{"key":"10.1111\/jam.13400-BIB0038|jam13400-cit-0038","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jep.2004.04.026","article-title":"Effect of Brazilian green propolis on the production of reactive oxygen species by stimulated neutrophils","volume":"94","author":"Sim\u00f5es","year":"2004","journal-title":"J Ethnopharmacol"},{"key":"10.1111\/jam.13400-BIB0039|jam13400-cit-0039","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0944-7113(00)80014-8","article-title":"A comparative multicenter study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV)","volume":"7","author":"Vynograd","year":"2000","journal-title":"Phytomedicine"},{"key":"10.1111\/jam.13400-BIB0040|jam13400-cit-0040","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1473-3099(05)70295-4","article-title":"The role of nasal carriage in Staphylococcus aureus infections","volume":"5","author":"Wertheim","year":"2005","journal-title":"Lancet Infect Dis"},{"key":"10.1111\/jam.13400-BIB0041|jam13400-cit-0041","doi-asserted-by":"crossref","first-page":"457D469","DOI":"10.1080\/10715760500053610","article-title":"In vitro biological properties of flavonoid conjugates found in\u00a0vivo","volume":"39","author":"Williamson","year":"2005","journal-title":"Free Rad Res"},{"key":"10.1111\/jam.13400-BIB0042|jam13400-cit-0042","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1016\/S0031-9422(00)83754-1","article-title":"Diterpene glycosides and other constituents from Argentinian Baccharis species","volume":"25","author":"Zdero","year":"1986","journal-title":"Phytochemistry"}],"container-title":["Journal of Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjam.13400","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/jam.13400\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T09:25:00Z","timestamp":1676366700000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jambio\/article\/122\/4\/911\/6714412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,12]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.1111\/jam.13400","archive":["Portico"],"relation":{},"ISSN":["1364-5072"],"issn-type":[{"value":"1364-5072","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3,12]]}}}