{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:52:44Z","timestamp":1790304764822,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T00:00:00Z","timestamp":1494892800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T00:00:00Z","timestamp":1494892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21590475"],"award-info":[{"award-number":["21590475"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24590516"],"award-info":[{"award-number":["24590516"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31272584"],"award-info":[{"award-number":["31272584"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Changbai Mountain Scholars Program, Jilin","award":["2013035"],"award-info":[{"award-number":["2013035"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Appl Microbiol"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1111\/jam.13462","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T17:07:10Z","timestamp":1491412030000},"page":"1672-1679","source":"Crossref","is-referenced-by-count":34,"title":["Biological characteristics of staphylococcal enterotoxin Q and its potential risk for food poisoning"],"prefix":"10.1093","volume":"122","author":[{"given":"D.-L.","family":"Hu","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine; Jilin University; Changchun Jiling China"},{"name":"Department of Zoonoses; Kitasato University School of Veterinary Medicine; Towada Aomori Japan"},{"name":"Department of Microbiology and Immunology; Hirosaki University Graduate School of Medicine; Hirosaki Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.K.","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Zoonoses; Kitasato University School of Veterinary Medicine; Towada Aomori Japan"},{"name":"Department of Microbiology and Immunology; Hirosaki University Graduate School of Medicine; Hirosaki Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Isayama","sequence":"additional","affiliation":[{"name":"Department of Zoonoses; Kitasato University School of Veterinary Medicine; Towada Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Zoonoses; Kitasato University School of Veterinary Medicine; Towada Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Okamura","sequence":"additional","affiliation":[{"name":"Department of Zoonoses; Kitasato University School of Veterinary Medicine; Towada Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.C.","family":"Lei","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine; Jilin University; Changchun Jiling China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.S.","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine; Jilin University; Changchun Jiling China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.-C.","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine; Jilin University; Changchun Jiling China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.Y.","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine; Jilin University; Changchun Jiling China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Cui","sequence":"additional","affiliation":[{"name":"College of Life Science; Dalian Minzu University; Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Nakane","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology; Hirosaki University Graduate School of Medicine; Hirosaki Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,5,16]]},"reference":[{"key":"10.1111\/jam.13462-BIB0500|jam13462-cit-0500","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3390\/toxins2071751","article-title":"Food Poisoning and Staphylococcus aureus Enterotoxins","volume":"2","author":"Argud\u00edn","year":"2010","journal-title":"Toxins (Basel)"},{"key":"10.1111\/jam.13462-BIB0001|jam13462-cit-0001","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1128\/AEM.07487-11","article-title":"Genotypes, exotoxin gene content, and antimicrobial resistance of Staphylococcus aureus strains recovered from foods and food handlers","volume":"78","author":"Argud\u00edn","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/jam.13462-BIB0002|jam13462-cit-0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0168-1605(00)00377-9","article-title":"Staphylococcal enterotoxins","volume":"61","author":"Balaban","year":"2000","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/jam.13462-BIB0003|jam13462-cit-0003","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.fm.2016.10.020","article-title":"Genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolated from milk and dairy products in South Italy","volume":"62","author":"Basanisi","year":"2017","journal-title":"Food Microbiol"},{"key":"10.1111\/jam.13462-BIB0004|jam13462-cit-0004","doi-asserted-by":"crossref","first-page":"334","DOI":"10.4049\/jimmunol.83.3.334","article-title":"Staphylococcal enterotoxin. Identification of a specific precipitating antibody with enterotoxin-neutralizing property","volume":"83","author":"Bergdoll","year":"1959","journal-title":"J Immunol"},{"key":"10.1111\/jam.13462-BIB0005|jam13462-cit-0005","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1128\/JB.79.6.849-856.1960","article-title":"Further serological studies of staphylococcal enterotoxin","volume":"79","author":"Casman","year":"1960","journal-title":"J Bacteriol"},{"key":"10.1111\/jam.13462-BIB0006|jam13462-cit-0006","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ijfoodmicro.2015.07.018","article-title":"Prevalence and diversity of enterotoxin genes with genetic background of Staphylococcus aureus isolates from different origins in China","volume":"211","author":"Chao","year":"2015","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/jam.13462-BIB0007|jam13462-cit-0007","doi-asserted-by":"crossref","first-page":"22839","DOI":"10.1074\/jbc.M201932200","article-title":"Zinc-mediated dimerization and its effect on activity and conformation of staphylococcal enterotoxin type C","volume":"277","author":"Chi","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1111\/jam.13462-BIB0008|jam13462-cit-0008","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1128\/CMR.13.1.16-34.2000","article-title":"Exotoxins of Staphylococcus aureus","volume":"13","author":"Dinges","year":"2000","journal-title":"Clin Microbiol Rev"},{"key":"10.1111\/jam.13462-BIB0009|jam13462-cit-0009","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0168-1605(88)90057-8","article-title":"Estimation of human dose of staphylococcal enterotoxin A from a large outbreak of staphylococcal food poisoning involving chocolate milk","volume":"7","author":"Evenson","year":"1988","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/jam.13462-BIB0010|jam13462-cit-0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2014.06.017","article-title":"Staphylococcus aureus food-poisoning outbreak associated with the consumption of ice-cream","volume":"187","author":"Fetsch","year":"2014","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/jam.13462-BIB0011|jam13462-cit-0011","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.4315\/0362-028X.JFP-13-190","article-title":"Staphylococcal poisoning foodborne outbreak: epidemiological investigation and strain genotyping","volume":"76","author":"Gallina","year":"2013","journal-title":"J Food Prot"},{"key":"10.1111\/jam.13462-BIB0012|jam13462-cit-0012","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/jam.13029","article-title":"Goblet cells are involved in translocation of staphylococcal enterotoxin A in the intestinal tissue of house musk shrew (Suncus murinus)","volume":"120","author":"Hirose","year":"2016","journal-title":"J Appl Microbiol"},{"key":"10.1111\/jam.13462-BIB0013|jam13462-cit-0013","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/j.1365-2958.1994.tb00481.x","article-title":"Investigation of the role of the disulphide bond in the activity and structure of staphylococcal enterotoxin C1","volume":"13","author":"Hovde","year":"1994","journal-title":"Mol Microbiol"},{"key":"10.1111\/jam.13462-BIB0014|jam13462-cit-0014","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ejphar.2013.08.050","article-title":"Mechanisms of staphylococcal enterotoxin-induced emesis","volume":"722","author":"Hu","year":"2014","journal-title":"Eur J Pharmacol"},{"key":"10.1111\/jam.13462-BIB0015|jam13462-cit-0015","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.4315\/0362-028X-62.11.1350","article-title":"Emesis in the shrew mouse (Suncus murinus) induced by peroral and intraperitoneal administration of staphylococcal enterotoxin A","volume":"62","author":"Hu","year":"1999","journal-title":"J Food Prot"},{"key":"10.1111\/jam.13462-BIB0016|jam13462-cit-0016","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1128\/IAI.71.1.567-570.2003","article-title":"Induction of emetic response to staphylococcal enterotoxins in the house musk shrew (Suncus murinus)","volume":"71","author":"Hu","year":"2003","journal-title":"Infect Immun"},{"key":"10.1111\/jam.13462-BIB0017|jam13462-cit-0017","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1111\/j.1462-5822.2007.00957.x","article-title":"Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1","volume":"9","author":"Hu","year":"2007","journal-title":"Cell Microbiol"},{"key":"10.1111\/jam.13462-BIB0018|jam13462-cit-0018","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1099\/jmm.0.2008\/002790-0","article-title":"Comparative prevalence of superantigenic toxin genes in meticillin-resistant and meticillin-susceptible Staphylococcus aureus isolates","volume":"57","author":"Hu","year":"2008","journal-title":"J Med Microbiol"},{"key":"10.1111\/jam.13462-BIB0019|jam13462-cit-0019","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1365-2672.2010.04927.x","article-title":"The superantigenic activity of toxic shock syndrome toxin-1 is resistant to heating and digestive enzymes","volume":"110","author":"Li","year":"2011","journal-title":"J Appl Microbiol"},{"key":"10.1111\/jam.13462-BIB0020|jam13462-cit-0020","first-page":"5736","article-title":"Molecular typing of Staphylococcus aureus isolate responsible for staphylococcal poisoning incident in homemade food","volume":"5","author":"Macori","year":"2016","journal-title":"Ital J Food Saf"},{"key":"10.1111\/jam.13462-BIB0021|jam13462-cit-0021","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev.micro.55.1.77","article-title":"Toxic shock syndrome and bacterial superantigens: an update","volume":"55","author":"McCormick","year":"2001","journal-title":"Annu Rev Microbiol"},{"key":"10.1111\/jam.13462-BIB0022|jam13462-cit-0022","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3390\/toxins8090268","article-title":"Organization and ELISA-based results of the first proficiency testing to evaluate the ability of European Union Laboratories to detect staphylococcal enterotoxin type B (SEB) in buffer and milk","volume":"8","author":"Nia","year":"2016","journal-title":"Toxins (Basel)"},{"key":"10.1111\/jam.13462-BIB0023|jam13462-cit-0023","doi-asserted-by":"crossref","first-page":"5540","DOI":"10.1128\/IAI.73.9.5540-5546.2005","article-title":"Characterization of novel staphylococcal enterotoxin-like toxin type P","volume":"73","author":"Omoe","year":"2005a","journal-title":"Infect Immun"},{"key":"10.1111\/jam.13462-BIB0024|jam13462-cit-0024","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.femsle.2005.04.007","article-title":"Comprehensive detection of classical and newly described staphylococcal superantigenic toxin genes by multiplex PCR","volume":"246","author":"Omoe","year":"2005b","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/jam.13462-BIB0025|jam13462-cit-0025","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1128\/IAI.00550-13","article-title":"Emetic potential of newly identified staphylococcal enterotoxin-like toxins","volume":"81","author":"Omoe","year":"2013","journal-title":"Infect Immun"},{"key":"10.1111\/jam.13462-BIB0026|jam13462-cit-0026","doi-asserted-by":"crossref","first-page":"4999","DOI":"10.1128\/IAI.00045-08","article-title":"Identification and characterization of two novel staphylococcal enterotoxins types S and T","volume":"76","author":"Ono","year":"2008","journal-title":"Infect Immun"},{"key":"10.1111\/jam.13462-BIB0027|jam13462-cit-0027","doi-asserted-by":"crossref","first-page":"7034","DOI":"10.1128\/AEM.01873-15","article-title":"Identification and characterization of a novel staphylococcal emetic toxin","volume":"81","author":"Ono","year":"2015","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/jam.13462-BIB0029|jam13462-cit-0029","doi-asserted-by":"crossref","first-page":"14033","DOI":"10.1021\/bi025977q","article-title":"Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins","volume":"41","author":"Orwin","year":"2002","journal-title":"Biochemistry"},{"key":"10.1111\/jam.13462-BIB0030|jam13462-cit-0030","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1111\/all.12010","article-title":"Role of imbalance of eicosanoid pathways and staphylococcal superantigens in chronic rhinosinusitis","volume":"67","author":"Pezato","year":"2012","journal-title":"Allergy"},{"key":"10.1111\/jam.13462-BIB0031|jam13462-cit-0031","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.3390\/toxins2082177","article-title":"Staphylococcal enterotoxins","volume":"2","author":"Pinchuk","year":"2010","journal-title":"Toxins (Basel)"},{"key":"10.1111\/jam.13462-BIB0032|jam13462-cit-0032","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1128\/JCM.00661-14","article-title":"Molecular epidemiology and identification of a Staphylococcus aureus clone causing food poisoning outbreaks in Japan","volume":"52","author":"Sato'o","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1111\/jam.13462-BIB0033|jam13462-cit-0033","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1093\/infdis\/143.4.509","article-title":"Identification and characterization of an exotoxin from Staphylococcus aureus associated with toxic-shock syndrome","volume":"143","author":"Schlievert","year":"1981","journal-title":"J Infect Dis"},{"key":"10.1111\/jam.13462-BIB0034|jam13462-cit-0034","doi-asserted-by":"crossref","first-page":"309","DOI":"10.7883\/yoken1952.27.309","article-title":"A consideration to immune doses of staphylococcal enterotoxin B to rabbits","volume":"27","author":"Shinagawa","year":"1974","journal-title":"Jpn J Med Sci Biol"},{"key":"10.1111\/jam.13462-BIB0035|jam13462-cit-0035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1348-0421.1994.tb01772.x","article-title":"Bacterial superantigens - mechanism of T cell activation by the superantigens and their role in the pathogenesis of infectious diseases","volume":"38","author":"Uchiyama","year":"1994","journal-title":"Microbiol Immunol"},{"key":"10.1111\/jam.13462-BIB0036|jam13462-cit-0036","doi-asserted-by":"crossref","first-page":"e1002271","DOI":"10.1371\/journal.ppat.1002271","article-title":"A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia","volume":"7","author":"Wilson","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1111\/jam.13462-BIB0037|jam13462-cit-0037","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3390\/toxins8070176","article-title":"A review of the methods for detection of Staphylococcus aureus enterotoxins","volume":"8","author":"Wu","year":"2016","journal-title":"Toxins"}],"container-title":["Journal of Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjam.13462","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/jam.13462\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:51:25Z","timestamp":1692751885000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jambio\/article\/122\/6\/1672\/6714060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,16]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"URL":"https:\/\/doi.org\/10.1111\/jam.13462","archive":["Portico"],"relation":{},"ISSN":["1364-5072"],"issn-type":[{"value":"1364-5072","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5,16]]}}}