{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T10:26:30Z","timestamp":1783765590997,"version":"3.55.0"},"reference-count":109,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"China Agriculture Research System of MOF and MARA","award":["CARS-18-ZJ0302"],"award-info":[{"award-number":["CARS-18-ZJ0302"]}]},{"DOI":"10.13039\/501100004189","name":"Max-Planck-Gesellschaft","doi-asserted-by":"publisher","award":["Partner Group"],"award-info":[{"award-number":["Partner Group"]}],"id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32022081"],"award-info":[{"award-number":["32022081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31970483"],"award-info":[{"award-number":["31970483"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["LZ22C170001"],"award-info":[{"award-number":["LZ22C170001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>L-tryptophan is an essential aromatic amino acid for the growth and development of animals. Studies about enteric L-tryptophan-producing bacteria are scarce. In this report, we characterized the probiotic potential of Enterococcus casseliflavus ECB140, focusing on its L-tryptophan production abilities.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>ECB140 strain was isolated from the silkworm gut and can survive under strong alkaline environmental conditions. Bacterial colonization traits (motility and biofilm) were examined and showed that only ECB140 produced flagellum and strong biofilms compared with other Enterococcus strains. Comparative genome sequence analyses showed that only ECB140 possessed a complete route for L-tryptophan synthesis among all 15 strains. High-performance liquid chromatography and qRT-PCR confirmed the capability of ECB140 to produce L-tryptophan. Besides, the genome also contains the biosynthesis pathways of several other essential amino acids, such as phenylalanine, threonine, valine, leucine, isoleucine and lysine. These results indicate that ECB140 has the ability to survive passage through the gut and could act as a candidate probiotic.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The study describes a novel, natural silkworm gut symbiont capable of producing L-tryptophan. Enterococcus casseliflavus ECB140 physical and genomic attributes offer possibilities for its colonization and provide L-tryptophan for lepidopteran insects.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/jam.15675","type":"journal-article","created":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T07:06:30Z","timestamp":1655622390000},"page":"1620-1635","source":"Crossref","is-referenced-by-count":36,"title":["Probiotic potentials of the silkworm gut symbiont Enterococcus casseliflavus ECB140, a promising L-tryptophan producer living inside the host"],"prefix":"10.1093","volume":"133","author":[{"given":"Xili","family":"Liang","sequence":"first","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintao","family":"He","sequence":"additional","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abrar","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingmeng","family":"Lu","sequence":"additional","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3331-5880","authenticated-orcid":false,"given":"Yongqi","family":"Shao","sequence":"additional","affiliation":[{"name":"Max Planck Partner Group, Institute of Sericulture and Apiculture, College of Animal Sciences Zhejiang University Hangzhou China"},{"name":"Key Laboratory for Molecular Animal Nutrition Ministry of Education Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"key":"2023011711341380200_jam15675-bib-0001","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.chembiol.2015.02.005","article-title":"Biosynthetic manipulation of tryptophan in bacteria: pathways and mechanisms","volume":"22","author":"Alkhalaf","year":"2015","journal-title":"Chemistry & Biology"},{"key":"2023011711341380200_jam15675-bib-0002","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Research"},{"key":"2023011711341380200_jam15675-bib-0003","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s13204-013-0266-1","article-title":"Antibiofilm efficacy of silver nanoparticles against biofilm of extended spectrum \u03b2-lactamase isolates of Escherichia coli and Klebsiella pneumoniae","volume":"4","author":"Ansari","year":"2014","journal-title":"Applied Nanoscience"},{"key":"2023011711341380200_jam15675-bib-0004","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/nrmicro2761","article-title":"The rise of the Enterococcus: beyond vancomycin resistance","volume":"10","author":"Arias","year":"2012","journal-title":"Nature Reviews Microbiology"},{"key":"2023011711341380200_jam15675-bib-0005","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3390\/molecules23020482","article-title":"Antimicrobial and antibiofilm activity and machine learning classification analysis of essential oils from different mediterranean plants against Pseudomonas aeruginosa","volume":"23","author":"Artini","year":"2018","journal-title":"Molecules"},{"key":"2023011711341380200_jam15675-bib-0006","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1007\/BF02154137","article-title":"Tryptophan production by mutant strains of Escherichia coli K-12","volume":"23","author":"Bandiera","year":"1967","journal-title":"Experientia"},{"key":"2023011711341380200_jam15675-bib-0007","doi-asserted-by":"crossref","first-page":"8766","DOI":"10.3390\/ijms21228776","article-title":"The uniqueness of tryptophan in biology: properties, metabolism, interactions and localization in proteins","volume":"21","author":"Barik","year":"2020","journal-title":"International Journal of Molecular Sciences"},{"key":"2023011711341380200_jam15675-bib-0008","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/jez.2057","article-title":"Suppression of tryptophan 2,3-dioxygenase produces a slow heartbeat phenotype in Drosophila melanogaster","volume":"325","author":"Beasley","year":"2016","journal-title":"Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology"},{"key":"2023011711341380200_jam15675-bib-0009","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/nar\/27.2.573","article-title":"Tandem repeats finder: a program to analyze DNA sequences","volume":"27","author":"Benson","year":"1999","journal-title":"Nucleic Acids Research"},{"key":"2023011711341380200_jam15675-bib-0010","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1128\/JCM.00795-08","article-title":"vanC gene-related intrinsic teicoplanin resistance detected in Enterococcus casseliflavus and E. gallinarum strains by the BD phoenix automated microbiology system","volume":"46","author":"Berktas","year":"2008","journal-title":"Journal of Clinical Microbiology"},{"key":"2023011711341380200_jam15675-bib-0011","first-page":"11","article-title":"Antioxidant effect of Tryptophan on biochemical parameters in the haemolymph and fat body of final instar larvae of silk insect, Bombyx mori","volume":"3","author":"Bhaskaran","year":"2015","journal-title":"Journal of Applied Biology & Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0012","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1046\/j.1365-3032.2002.00301.x","article-title":"Relating genotype and phenotype for tryptophan synthesis in an aphid-bacterial symbiosis","volume":"27","author":"Birkle","year":"2002","journal-title":"Physiological Entomology"},{"key":"2023011711341380200_jam15675-bib-0013","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1126\/science.277.5331.1453","article-title":"The complete genome sequence of Escherichia coli K-12","volume":"277","author":"Blattner","year":"1997","journal-title":"Science"},{"key":"2023011711341380200_jam15675-bib-0014","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1128\/IAI.00279-07","article-title":"Enterococcal leucine-rich repeat-containing protein involved in virulence and host inflammatory response","volume":"75","author":"Brinster","year":"2007","journal-title":"Infection and Immunity"},{"key":"2023011711341380200_jam15675-bib-0015","doi-asserted-by":"crossref","first-page":"M2799","DOI":"10.1111\/1750-3841.13523","article-title":"Diversity of antibiotic resistance genes in Enterococcus strains isolated from ready-to-eat meat products","volume":"81","author":"Chajecka-Wierzchowska","year":"2016","journal-title":"Journal of Food Science"},{"key":"2023011711341380200_jam15675-bib-0016","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.lwt.2016.01.034","article-title":"Virulence factors, antimicrobial resistance and biofilm formation in Enterococcus spp. isolated from retail shrimps","volume":"69","author":"Chajecka-Wierzchowska","year":"2016","journal-title":"Lwt-Food Science and Technology"},{"key":"2023011711341380200_jam15675-bib-0017","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.molp.2020.06.009","article-title":"TBtools: an integrative toolkit developed for interactive analyses of big biological data","volume":"13","author":"Chen","year":"2020","journal-title":"Molecular Plant"},{"key":"2023011711341380200_jam15675-bib-0018","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.joen.2018.05.008","article-title":"Inhibition of Enterococcus faecalis growth and biofilm formation by molecule targeting cyclic di-AMP synthetase activity","volume":"44","author":"Chen","year":"2018","journal-title":"Journal of Endodontia"},{"key":"2023011711341380200_jam15675-bib-0019","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00253-016-7772-5","article-title":"Rational design and metabolic analysis of Escherichia coli for effective production of L-tryptophan at high concentration","volume":"101","author":"Chen","year":"2017","journal-title":"Applied Microbiology and Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0020","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1007\/s13213-012-0419-6","article-title":"Effect of feeding strategy on L-tryptophan production by recombinant Escherichia coli","volume":"62","author":"Cheng","year":"2012","journal-title":"Annales de Microbiologie"},{"key":"2023011711341380200_jam15675-bib-0021","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/nmeth.2474","article-title":"Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data","volume":"10","author":"Chin","year":"2013","journal-title":"Nature Methods"},{"key":"2023011711341380200_jam15675-bib-0022","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1128\/jb.98.1.167-171.1969","article-title":"Tryptophanase in diverse bacterial species","volume":"98","author":"DeMoss","year":"1969","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0023","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.joen.2007.02.016","article-title":"Biofilm formation of oral and endodontic Enterococcus faecalis","volume":"33","author":"Duggan","year":"2007","journal-title":"Journal of Endodontia"},{"key":"2023011711341380200_jam15675-bib-0024","first-page":"1","volume-title":"Pathogenesis, molecular biology, and antibiotic resistance","author":"Facklam","year":"2002"},{"key":"2023011711341380200_jam15675-bib-0025","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.micpath.2017.05.014","article-title":"Phenotypic and genotypic study of biofilm formation in Enterococci isolated from urinary tract infections","volume":"108","author":"Fallah","year":"2017","journal-title":"Microbial Pathogenesis"},{"key":"2023011711341380200_jam15675-bib-0026","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijfoodmicro.2011.08.014","article-title":"Enterococci as probiotics and their implications in food safety","volume":"151","author":"Franz","year":"2011","journal-title":"International Journal of Food Microbiology"},{"key":"2023011711341380200_jam15675-bib-0027","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1136\/jcp.42.8.872","article-title":"New method for detecting slime production by coagulase negative staphylococci","volume":"42","author":"Freeman","year":"1989","journal-title":"Journal of Clinical Pathology"},{"key":"2023011711341380200_jam15675-bib-0028","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jmb.2008.04.012","article-title":"Polar, peritrichous, and lateral flagella belong to three distinguishable flagellar families","volume":"379","author":"Fujii","year":"2008","journal-title":"Journal of Molecular Biology"},{"key":"2023011711341380200_jam15675-bib-0029","doi-asserted-by":"crossref","first-page":"D121","DOI":"10.1093\/nar\/gki081","article-title":"Rfam: annotating non-coding RNAs in complete genomes","volume":"33","author":"Griffiths-Jones","year":"2005","journal-title":"Nucleic Acids Research"},{"key":"2023011711341380200_jam15675-bib-0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1475-2859-11-30","article-title":"One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan in Escherichia coli","volume":"11","author":"Gu","year":"2012","journal-title":"Microbial Cell Factories"},{"key":"2023011711341380200_jam15675-bib-0031","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.foodcont.2008.11.001","article-title":"Use of lactic acid bacteria (LAB) biofilms for the control of Listeria monocytogenes in a small-scale model","volume":"20","author":"Guerrieri","year":"2009","journal-title":"Food Control"},{"key":"2023011711341380200_jam15675-bib-0032","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/1751-7915.12306","article-title":"Probiotic properties of Enterococcus strains isolated from traditional naturally fermented cream in China","volume":"9","author":"Guo","year":"2016","journal-title":"Microbial Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0033","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jinsphys.2006.09.004","article-title":"The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis","volume":"53","author":"Han","year":"2007","journal-title":"Journal of Insect Physiology"},{"key":"2023011711341380200_jam15675-bib-0034","doi-asserted-by":"crossref","first-page":"8233","DOI":"10.1128\/JB.01205-07","article-title":"Enterococcal surface protein Esp is important for biofilm formation of Enterococcus faecium E1162","volume":"189","author":"Heikens","year":"2007","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0035","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0304-4165(02)00207-6","article-title":"Regulation of glutamine metabolism during the development of Bombyx mori larvae","volume":"1571","author":"Hirayama","year":"2002","journal-title":"Biochimica et Biophysica Acta"},{"key":"2023011711341380200_jam15675-bib-0036","first-page":"1","article-title":"Phylogenomic evidence supports past endosymbiosis, intracellular and horizontal gene transfer in Cryptosporidium parvum","volume":"5","author":"Huang","year":"2004","journal-title":"Genome Biology"},{"key":"2023011711341380200_jam15675-bib-0037","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1128\/iai.45.2.528-530.1984","article-title":"Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice","volume":"45","author":"Ike","year":"1984","journal-title":"Infection and Immunity"},{"key":"2023011711341380200_jam15675-bib-0038","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1128\/AEM.65.6.2497-2502.1999","article-title":"Hyperproduction of tryptophan by Corynebacterium glutamicum with the modified pentose phosphate pathway","volume":"65","author":"Ikeda","year":"1999","journal-title":"Applied and Environmental Microbiology"},{"key":"2023011711341380200_jam15675-bib-0039","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/mbo3.41","article-title":"Immunomodulatory effects of heat-killed Enterococcus faecalis TH10 on murine macrophage cells","volume":"1","author":"Itoh","year":"2012","journal-title":"Microbiology"},{"key":"2023011711341380200_jam15675-bib-0040","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1128\/JCM.03617-13","article-title":"Real-time whole-genome sequencing for routine typing, surveillance, and outbreak detection of verotoxigenic Escherichia coli","volume":"52","author":"Joensen","year":"2014","journal-title":"Journal of Clinical Microbiology"},{"key":"2023011711341380200_jam15675-bib-0041","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0022-1910(79)90113-6","article-title":"Ommochrome formation and kynurenine excretion in Pieris brassicae - relation to tryptophan supply on an artificial diet","volume":"25","author":"Kayser","year":"1979","journal-title":"Journal of Insect Physiology"},{"key":"2023011711341380200_jam15675-bib-0042","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0968-0004(00)01626-1","article-title":"How proteins adapt to a membrane-water interface","volume":"25","author":"Killian","year":"2000","journal-title":"Trends in Biochemical Sciences"},{"key":"2023011711341380200_jam15675-bib-0043","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1002\/bit.26797","article-title":"Metabolic engineering of Escherichia coli for the enhanced production of l-tyrosine","volume":"115","author":"Kim","year":"2018","journal-title":"Biotechnology and Bioengineering"},{"key":"2023011711341380200_jam15675-bib-0044","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1085\/jgp.200709829","article-title":"Concerning tryptophan and protein-bilayer interactions","volume":"130","author":"Koeppe","year":"2007","journal-title":"The Journal of General Physiology"},{"key":"2023011711341380200_jam15675-bib-0045","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/nutrit\/nuy056","article-title":"Yogurt and other fermented foods as sources of health-promoting bacteria","volume":"76","author":"Kok","year":"2018","journal-title":"Nutrition Reviews"},{"key":"2023011711341380200_jam15675-bib-0046","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1101\/gr.092759.109","article-title":"Circos: an information aesthetic for comparative genomics","volume":"19","author":"Krzywinski","year":"2009","journal-title":"Genome Research"},{"key":"2023011711341380200_jam15675-bib-0047","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.margen.2015.11.001","article-title":"First Azospirillum genome from aquatic environments: Whole-genome sequence of Azospirillum thiophilum BV-S(T), a novel diazotroph harboring a capacity of sulfur-chemolithotrophy from a sulfide spring","volume":"25","author":"Kwak","year":"2016","journal-title":"Marine Genomics"},{"key":"2023011711341380200_jam15675-bib-0048","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1093\/nar\/gkm160","article-title":"RNAmmer: consistent and rapid annotation of ribosomal RNA genes","volume":"35","author":"Lagesen","year":"2007","journal-title":"Nucleic Acids Research"},{"key":"2023011711341380200_jam15675-bib-0049","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1128\/jb.80.5.714-718.1960","article-title":"Motile enterococci (Streptococcus faecium var. mobilis var. n.) isolated from grass silage","volume":"80","author":"Langston","year":"1960","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0050","doi-asserted-by":"crossref","first-page":"e01401","DOI":"10.1128\/AEM.01401-20","article-title":"Gut bacteria mediate utrient availability in Drosophila diets","volume":"87","author":"Lesperance","year":"2020","journal-title":"Applied and Environmental Microbiology"},{"key":"2023011711341380200_jam15675-bib-0051","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1099\/mic.0.064139-0","article-title":"Indole production by the tryptophanase TnaA in Escherichia coli is determined by the amount of exogenous tryptophan","volume":"159","author":"Li","year":"2013","journal-title":"Microbiology (Read)"},{"key":"2023011711341380200_jam15675-bib-0052","doi-asserted-by":"crossref","first-page":"6155","DOI":"10.1007\/s00253-017-8373-7","article-title":"Novel vitamin B12-producing Enterococcus spp. and preliminary in vitro evaluation of probiotic potentials","volume":"101","author":"Li","year":"2017","journal-title":"Applied Microbiology and Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0053","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.synbio.2020.06.009","article-title":"Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways","volume":"5","author":"Li","year":"2020","journal-title":"Synthetic and Systems Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0054","doi-asserted-by":"crossref","first-page":"4951","DOI":"10.1007\/s00253-018-8953-1","article-title":"Insect symbionts as valuable grist for the biotechnological mill: an alkaliphilic silkworm gut bacterium for efficient lactic acid production","volume":"102","author":"Liang","year":"2018","journal-title":"Applied Microbiology and Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0055","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1590\/S1517-83822014000300029","article-title":"Influence of glyphosate in planktonic and biofilm growth of Pseudomonas aeruginosa","volume":"45","author":"Lima","year":"2014","journal-title":"Brazilian Journal of Microbiology"},{"key":"2023011711341380200_jam15675-bib-0056","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1099\/ijsem.0.003522","article-title":"Lactobacillus suantsaicola sp. nov. and Lactobacillus suantsaiihabitans sp. nov., isolated from suan-tsai, a traditional fermented mustard green product of Taiwan","volume":"70","author":"Lin","year":"2020","journal-title":"International Journal of Systematic and Evolutionary Microbiology"},{"key":"2023011711341380200_jam15675-bib-0057","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1021\/sb5002505","article-title":"Engineering bacterial phenylalanine 4-hydroxylase for microbial synthesis of human neurotransmitter precursor 5-hydroxytryptophan","volume":"3","author":"Lin","year":"2014","journal-title":"ACS Synthetic Biology"},{"key":"2023011711341380200_jam15675-bib-0058","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.14202\/vetworld.2021.2244-2250","article-title":"Immunomodulatory, behavioral, and nutritional response of tryptophan application on poultry","volume":"14","author":"Linh","year":"2021","journal-title":"Veterinary World"},{"key":"2023011711341380200_jam15675-bib-0059","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/0022-1910(71)90144-2","article-title":"Tryptophan catabolism in silkworm metamorphosis: changes in total matter, DNA, free, and protein-bound tryptophan","volume":"17","author":"Linzen","year":"1971","journal-title":"Journal of Insect Physiology"},{"key":"2023011711341380200_jam15675-bib-0060","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jbiotec.2015.11.012","article-title":"Complete genome sequence of Enterococcus durans KLDS6.0930, a strain with probiotic properties","volume":"217","author":"Liu","year":"2016","journal-title":"Journal of Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2019.103344","article-title":"Inhibition of biofilm formation and exopolysaccharide synthesis of Enterococcus faecalis by phenyllactic acid","volume":"86","author":"Liu","year":"2020","journal-title":"Food Microbiology"},{"key":"2023011711341380200_jam15675-bib-0062","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1574-6968.2007.00836.x","article-title":"Adhesion to medical device materials and biofilm formation capability of some species of enterococci in different physiological states","volume":"274","author":"Lleo","year":"2007","journal-title":"FEMS Microbiology Letters"},{"key":"2023011711341380200_jam15675-bib-0063","doi-asserted-by":"crossref","first-page":"W54","DOI":"10.1093\/nar\/gkw413","article-title":"tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes","volume":"44","author":"Lowe","year":"2016","journal-title":"Nucleic Acids Research"},{"key":"2023011711341380200_jam15675-bib-0064","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00253-006-0792-9","article-title":"L-tyrosine production by deregulated strains of Escherichia coli","volume":"75","author":"Lutke-Eversloh","year":"2007","journal-title":"Applied Microbiology and Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0065","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1111\/j.1462-2920.2009.01881.x","article-title":"Enterococcus faecalis with the gelatinase phenotype regulated by the fsr operon and with biofilm-forming capacity are common in the agricultural environment","volume":"11","author":"Macovei","year":"2009","journal-title":"Environmental Microbiology"},{"key":"2023011711341380200_jam15675-bib-0066","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0022-2836(80)80017-9","article-title":"Energetics of flagellar rotation in bacteria","volume":"138","author":"Manson","year":"1980","journal-title":"Journal of Molecular Biology"},{"key":"2023011711341380200_jam15675-bib-0067","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1128\/am.24.4.575-580.1972","article-title":"Enterococci in insects","volume":"24","author":"Martin","year":"1972","journal-title":"Applied Microbiology"},{"key":"2023011711341380200_jam15675-bib-0068","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1017\/S0007114510004319","article-title":"Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects","volume":"105","author":"Messaoudi","year":"2011","journal-title":"The British Journal of Nutrition"},{"key":"2023011711341380200_jam15675-bib-0069","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1093\/ajcn\/70.6.1046","article-title":"Incorporation of urea and ammonia nitrogen into ileal and fecal microbial proteins and plasma free amino acids in normal men and ileostomates","volume":"70","author":"Metges","year":"1999","journal-title":"The American Journal of Clinical Nutrition"},{"key":"2023011711341380200_jam15675-bib-0070","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1107\/S2052252519005955","article-title":"Conservation of the structure and function of bacterial tryptophan synthases","volume":"6","author":"Michalska","year":"2019","journal-title":"Iucrj"},{"key":"2023011711341380200_jam15675-bib-0071","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1017\/S0007114500000647","article-title":"The transfer of 15N from urea to lysine in the human infant","volume":"83","author":"Millward","year":"2000","journal-title":"The British Journal of Nutrition"},{"key":"2023011711341380200_jam15675-bib-0072","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2331\/fishsci.63.188","article-title":"Motile enterococci isolated from fishery products","volume":"63","author":"Morii","year":"1997","journal-title":"Fisheries Science"},{"key":"2023011711341380200_jam15675-bib-0073","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1084\/jem.189.9.1363","article-title":"Inhibition of T cell proliferation by macrophage tryptophan catabolism","volume":"189","author":"Munn","year":"1999","journal-title":"The Journal of Experimental Medicine"},{"key":"2023011711341380200_jam15675-bib-0074","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.281.5380.1191","article-title":"Prevention of allogeneic fetal rejection by tryptophan catabolism","volume":"281","author":"Munn","year":"1998","journal-title":"Science"},{"key":"2023011711341380200_jam15675-bib-0075","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.3390\/nu7042930","article-title":"The role of microbial amino acid metabolism in host metabolism","volume":"7","author":"Neis","year":"2015","journal-title":"Nutrients"},{"key":"2023011711341380200_jam15675-bib-0076","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00318-11","article-title":"Comparative genomics of enterococci: variation in Enterococcus faecalis, clade structure in E. faecium, and defining characteristics of E. gallinarum and E. casseliflavus","volume":"3","author":"Palmer","year":"2012","journal-title":"mBio"},{"key":"2023011711341380200_jam15675-bib-0077","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.3390\/microorganisms8091274","article-title":"Processing wastewaters from Spanish-style cv. chalkidiki green olives: a potential source of Enterococcus casseliflavus and hydroxytyrosol","volume":"8","author":"Papadaki","year":"2020","journal-title":"Microorganisms"},{"key":"2023011711341380200_jam15675-bib-0078","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4137\/IJTR.S1129","article-title":"Assessment of the potential role of tryptophan as the precursor of serotonin and melatonin for the aged sleep-wake cycle and immune function: Streptopelia risoria as a model","volume":"2","author":"Paredes","year":"2009","journal-title":"International journal of tryptophan research"},{"key":"2023011711341380200_jam15675-bib-0079","doi-asserted-by":"crossref","first-page":"10040","DOI":"10.1073\/pnas.94.19.10040","article-title":"Bacterial resistance to vancomycin: overproduction, purification, and characterization of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase","volume":"94","author":"Park","year":"1997","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"2023011711341380200_jam15675-bib-0080","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/1574-6941.12138","article-title":"Bacteriocins with a broader antimicrobial spectrum prevail in enterococcal symbionts isolated from the hoopoe's uropygial gland","volume":"85","author":"Ruiz-Rodriguez","year":"2013","journal-title":"FEMS Microbiology Ecology"},{"key":"2023011711341380200_jam15675-bib-0081","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.10589","article-title":"Optimization of L-tryptophan biosynthesis from L-serine of processed Iranian beet and cane molasses and indole by induced Escherichia coli ATCC 11303 cells","volume":"7","author":"Sadeghiyan-Rizi","year":"2014","journal-title":"Jundishapur Journal of Microbiology"},{"key":"2023011711341380200_jam15675-bib-0082","first-page":"188","article-title":"Preliminary study on cost-effective L-tryptophan production from indole and L-serine by E. coli cells","volume":"8","author":"Sadeghiyan-Rizi","year":"2016","journal-title":"Avicenna Journal of Medical Biotechnology"},{"key":"2023011711341380200_jam15675-bib-0083","doi-asserted-by":"crossref","first-page":"13538","DOI":"10.1073\/pnas.1206346109","article-title":"Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli","volume":"109","author":"Santos","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"2023011711341380200_jam15675-bib-0084","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005429","article-title":"Beg, borrow and steal: three aspects of horizontal gene transfer in the protozoan parasite, Cryptosporidium parvum","volume":"12","author":"Sateriale","year":"2016","journal-title":"PLoS Pathogens"},{"key":"2023011711341380200_jam15675-bib-0085","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/protein\/5.3.213","article-title":"The functions of tryptophan residues in membrane proteins","volume":"5","author":"Schiffer","year":"1992","journal-title":"Protein Engineering"},{"key":"2023011711341380200_jam15675-bib-0086","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/jsfa.6721","article-title":"Whole-genome based validation of the adaptive properties of Indian origin probiotic Lactobacillus helveticus MTCC 5463","volume":"95","author":"Senan","year":"2015","journal-title":"Journal of the Science of Food and Agriculture"},{"key":"2023011711341380200_jam15675-bib-0087","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1365-3032.1992.tb01022.x","article-title":"Glutamine synthetase activity during embryonic and larval development of the silkworm Bombyx mori L. and role of a JH analogue","volume":"17","author":"Seshachalam","year":"1992","journal-title":"Physiological Entomology"},{"key":"2023011711341380200_jam15675-bib-0088","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.chembiol.2016.11.015","article-title":"Symbiont-derived antimicrobials contribute to the control of the lepidopteran gut microbiota","volume":"24","author":"Shao","year":"2017","journal-title":"Cell Chemical Biology"},{"key":"2023011711341380200_jam15675-bib-0089","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12941-019-0340-y","article-title":"Extended spectrum beta-lactamase producing uropathogenic Escherichia coli and the correlation of biofilm with antibiotics resistance in Nepal","volume":"18","author":"Shrestha","year":"2019","journal-title":"Annals of Clinical Microbiology and Antimicrobials"},{"key":"2023011711341380200_jam15675-bib-0090","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1086\/314453","article-title":"Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model","volume":"178","author":"Singh","year":"1998","journal-title":"The Journal of Infectious Diseases"},{"key":"2023011711341380200_jam15675-bib-0091","doi-asserted-by":"crossref","first-page":"11204","DOI":"10.1038\/s41598-019-47602-w","article-title":"Biofilm formation capacity and presence of virulence factors among commensal Enterococcus spp. from wild birds","volume":"9","author":"Stepien-Pysniak","year":"2019","journal-title":"Scientific Reports"},{"key":"2023011711341380200_jam15675-bib-0092","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF00689210","article-title":"Tryptophan-metabolism during development of the stick Insect, Carausius morosus Br. tissue distribution and interrelationships of metabolites of the kynurenine pathway","volume":"137","author":"Stratakis","year":"1980","journal-title":"Journal of Comparative Physiology"},{"key":"2023011711341380200_jam15675-bib-0093","first-page":"101","volume-title":"The enterococci: pathogenesis, molecular biology, and antibiotic resistance","author":"Tannock","year":"2002"},{"key":"2023011711341380200_jam15675-bib-0094","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1096\/fasebj.5.11.1907934","article-title":"Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism","volume":"5","author":"Taylor","year":"1991","journal-title":"The FASEB Journal"},{"key":"2023011711341380200_jam15675-bib-0095","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1128\/jb.105.2.676-678.1971","article-title":"Carotenoids in yellow-pigmented enterococci","volume":"105","author":"Taylor","year":"1971","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0096","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1084\/jem.20020052","article-title":"Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites","volume":"196","author":"Terness","year":"2002","journal-title":"The Journal of Experimental Medicine"},{"key":"2023011711341380200_jam15675-bib-0097","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.bpj.2016.05.053","article-title":"Visualizing flagella while tracking bacteria","volume":"111","author":"Turner","year":"2016","journal-title":"Biophysical Journal"},{"key":"2023011711341380200_jam15675-bib-0098","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/978-1-4615-4709-9_101","article-title":"Tryptophans in membrane proteins. X-ray crystallographic analyses","volume":"467","author":"Wallace","year":"1999","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"2023011711341380200_jam15675-bib-0099","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/nchembio.2420","article-title":"A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase","volume":"13","author":"Wellington","year":"2017","journal-title":"Nature Chemical Biology"},{"key":"2023011711341380200_jam15675-bib-0100","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1128\/JB.01398-06","article-title":"Translation control of trpG from transcripts originating from the folate operon promoter of Bacillus subtilis is influenced by translation-mediated displacement of bound TRAP, while translation control of transcripts originating from a newly identified trpG promoter is not","volume":"189","author":"Yakhnin","year":"2007","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0101","doi-asserted-by":"crossref","first-page":"4272","DOI":"10.1128\/jb.177.15.4272-4278.1995","article-title":"Translation of trpG in Bacillus subtilis is regulated by the trp RNA-binding attenuation protein (TRAP)","volume":"177","author":"Yang","year":"1995","journal-title":"Journal of Bacteriology"},{"key":"2023011711341380200_jam15675-bib-0102","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.2147\/IDR.S180254","article-title":"Molecular characteristics and comparative genomics analysis of a clinical Enterococcus casseliflavus with a resistance plasmid","volume":"11","author":"Yin","year":"2018","journal-title":"Infection and Drug Resistance"},{"key":"2023011711341380200_jam15675-bib-0103","doi-asserted-by":"crossref","first-page":"5371","DOI":"10.1007\/s11033-021-06540-5","article-title":"Genomic-based characterization of Enterococcus spp.: an emerging pathogen isolated from human gut","volume":"48","author":"Younus","year":"2021","journal-title":"Molecular Biology Reports"},{"key":"2023011711341380200_jam15675-bib-0104","first-page":"613","article-title":"Conversion L-tryptophan to melatonin in the gastrointestinal tract: the new high performance liquid chromatography method enabling simultaneous determination of six metabolites of L-tryptophan by native fluorescence and UV-VIS detection","volume":"63","author":"Zagajewski","year":"2012","journal-title":"Journal of Physiology and Pharmacology"},{"key":"2023011711341380200_jam15675-bib-0105","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s00726-021-03009-4","article-title":"Disruption of kynurenine pathway reveals physiological importance of tryptophan catabolism in Henosepilachna vigintioctopunctata","volume":"53","author":"Ze","year":"2021","journal-title":"Amino Acids"},{"key":"2023011711341380200_jam15675-bib-0106","doi-asserted-by":"crossref","first-page":"4658","DOI":"10.1016\/j.csbj.2021.08.020","article-title":"Contribution of sample processing to gut microbiome analysis in the model Lepidoptera, silkworm Bombyx mori","volume":"19","author":"Zhang","year":"2021","journal-title":"Computational and Structural Biotechnology Journal"},{"key":"2023011711341380200_jam15675-bib-0107","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/s13068-018-1201-1","article-title":"Pan-genome analyses of 24 Shewanella strains re-emphasize the diversification of their functions yet evolutionary dynamics of metal-reducing pathway","volume":"11","author":"Zhong","year":"2018","journal-title":"Biotechnology for Biofuels"},{"key":"2023011711341380200_jam15675-bib-0108","doi-asserted-by":"crossref","DOI":"10.1016\/j.jip.2022.107736","article-title":"Identification of key metabolic pathways reprogrammed by BmNPV in silkworm Bombyx mori","volume":"190","author":"Zhou","year":"2022","journal-title":"Journal of Invertebrate Pathology"},{"key":"2023011711341380200_jam15675-bib-0109","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1186\/1471-2164-11-628","article-title":"Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria","volume":"11","author":"Zucko","year":"2010","journal-title":"BMC Genomics"}],"container-title":["Journal of Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jam.15675","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jam.15675","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jambio\/article-pdf\/133\/3\/1620\/48734300\/jambio1620.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jambio\/article-pdf\/133\/3\/1620\/48734300\/jambio1620.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T16:03:51Z","timestamp":1673971431000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jambio\/article\/133\/3\/1620\/6989162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":109,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,9,1]]},"published-print":{"date-parts":[[2022,9,1]]}},"URL":"https:\/\/doi.org\/10.1111\/jam.15675","relation":{},"ISSN":["1365-2672","1364-5072"],"issn-type":[{"value":"1365-2672","type":"electronic"},{"value":"1364-5072","type":"print"}],"subject":[],"published-other":{"date-parts":[[2022,9,1]]},"published":{"date-parts":[[2022,9,1]]}}}