{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T18:34:47Z","timestamp":1788978887297,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T00:00:00Z","timestamp":1408320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Academic Health Science Collaboration NISCHR (AHSC) Clinical Research Fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the effectiveness of epilepsy self\u2010management interventions and explore the views and experiences of medication and seizures by children and young people.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Experiencing seizures and side\u2010effects from anti\u2010epileptic medicines have negative impacts on children and young people managing their epilepsy. Children commonly experiment with not taking epilepsy medication as prescribed and engage in unhealthy lifestyles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design\/Review\u00a0Methods<\/jats:title><jats:p>Mixed\u2010method systematic review with theory development. Cochrane quantitative methods and thematic synthesis of qualitative and survey evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>Eight databases were searched from earliest dates to July 2013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen studies were included. Meta\u2010analysis was not possible. Zero of nine intervention studies showed improvement in anti\u2010epilepsy medication adherence. Skill\u2010based behavioural techniques with activities such as role play and goal setting with young people increased epilepsy knowledge and seizure self\u2010management (small effects). Intervention studies were methodologically weak and no studies reported if improvement in self\u2010management was sustained over time. Synthesis of nine qualitative and one mixed\u2010method studies generated six themes encapsulating anti\u2010epilepsy medication and epilepsy effects. There was a lack of fidelity between intervention programme theories and what children and young people found difficult with medication self\u2010management and managing the effects of epilepsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children and young people knowingly and\/or unknowingly take risks with their epilepsy and give reasoned explanations for doing so. There are no effective interventions to change epilepsy medication adherence behaviours. There is an urgent need for more innovative and individually tailored interventions to address specific challenges to epilepsy self\u2010management as identified by children and young people themselves.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jan.12511","type":"journal-article","created":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T05:04:34Z","timestamp":1408338274000},"page":"478-497","source":"Crossref","is-referenced-by-count":18,"title":["Systematic review of epilepsy self\u2010management interventions integrated with a synthesis of children and young people's views and experiences"],"prefix":"10.1111","volume":"71","author":[{"given":"Sheila A.","family":"Lewis","sequence":"first","affiliation":[{"name":"Centre for Health\u2010Related Research School of Healthcare Sciences Bangor University UK"},{"name":"The Walton Centre NHS Foundation Trust Betsi Cadwaladr University Health Board Glan Clwyd Hospital North Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Noyes","sequence":"additional","affiliation":[{"name":"Health Services Research and Child Health Centre for Health\u2010Related Research School of Healthcare Sciences Bangor University UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Hastings","sequence":"additional","affiliation":[{"name":"Centre for Educational Development Appraisal and Research University of Warwick UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732307307548"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809332396"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2007.11.001"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.29085\/9781856047852.007","volume-title":"Evidence Based Practice for Information Professionals: A Handbook","author":"Booth A.","year":"2004"},{"key":"e_1_2_11_6_1","volume-title":"The Critical Appraisal Skills Programme. 10 Questions to Help You Make Sense of Qualitative Research","author":"CASP","year":"2002"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2702.2009.02966.x"},{"key":"e_1_2_11_8_1","volume-title":"Living Well with Epilepsy II report of the 2003 National Conference on Public Health and Epilepsy: Priorities for a public health agenda on epilepsy [text in PDF format]","author":"Chronic Disease Directors, Epilepsy Foundation of America, National Association of Epilepsy Centres","year":"2004"},{"key":"e_1_2_11_9_1","unstructured":"Cochrane Collaboration Qualitative and Implementation Methods Group(2013) Retrieved fromhttp:\/\/cqrmg.cochrane.org\/on July 2013."},{"key":"e_1_2_11_10_1","volume-title":"Data Collection Form","author":"Cochrane Effective Practice and Organisation of Care Review Group (EPOC)","year":"2012"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.7748\/ns2011.06.25.43.48.c8596"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrdd.10035"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1985.tb05654.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.175125"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01376517-200302000-00008"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2005.07.004"},{"key":"e_1_2_11_17_1","unstructured":"Evidence for Policy and Practice Information Co\u2010ordination Centre (EPPI Centre)Social Science Research Unit.Institute of Education University of London. 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