{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:20:06Z","timestamp":1790338806631,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T00:00:00Z","timestamp":1444780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005499","name":"Oncology Nursing Society Foundation","doi-asserted-by":"publisher","award":["Re39"],"award-info":[{"award-number":["Re39"]}],"id":[{"id":"10.13039\/100005499","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To report a study protocol that refines then examines feasibility, preliminary efficacy and satisfaction of <jats:styled-content style=\"fixed-case\">ADHERE<\/jats:styled-content>, an intervention using motivational interviewing and brief cognitive behaviorial therapy as a mechanism for goal\u2010oriented systematic patient education to promote symptom management and adherence among cancer patients prescribed oral anti\u2010cancer agents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Cancer treatment with oral anti\u2010cancer agents shifts responsibility for managing treatment from clinicians in supervised cancer centres to patients and their caregivers. Thus, a need exists to standardize start\u2010of\u2010care to support patient self\u2010management of care at home.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A two\u2010phase quasi\u2010experimental sequential design with repeated measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010five adult patients newly prescribed an oral anti\u2010cancer agent will be recruited from three community cancer centres. Phase 1 will enrol five patients to refine the <jats:styled-content style=\"fixed-case\">ADHERE<\/jats:styled-content> intervention prior to testing. After completion, Phase 2 will enrol 30 patients who receive usual care. Advanced practice nurses will then be trained. Thirty patients will be then enrolled in the intervention group and provided <jats:styled-content style=\"fixed-case\">ADHERE<\/jats:styled-content>, a 4\u2010week intervention using semi\u2010structured interactions (initial face\u2010to\u2010face session and once a week phone sessions over 3 weeks) and a Toolkit to promote self\u2010management of care. Outcome measures include: oral anti\u2010cancer agents adherence rate, symptom presence and severity, feasibility and satisfaction with <jats:styled-content style=\"fixed-case\">ADHERE<\/jats:styled-content>. This protocol was approved January 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This nurse\u2010led intervention has the potential to standardize the start\u2010of\u2010care training for the patients to self\u2010manage when oral anti\u2010cancer agents for treatment were prescribed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jan.12828","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T05:38:52Z","timestamp":1444801132000},"page":"409-420","source":"Crossref","is-referenced-by-count":11,"title":["A trial examining an advanced practice nurse intervention to promote medication adherence and symptom management in adult cancer patients prescribed oral anti\u2010cancer agents: study protocol"],"prefix":"10.1111","volume":"72","author":[{"given":"Sandra L.","family":"Spoelstra","sequence":"first","affiliation":[{"name":"Grand Valley State University Kirkhof College of Nursing Grand Rapids Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peggy S.","family":"Burhenn","sequence":"additional","affiliation":[{"name":"City of Hope National Medical Center Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"DeKoekkoek","sequence":"additional","affiliation":[{"name":"Michigan State University College of Nursing East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Schueller","sequence":"additional","affiliation":[{"name":"Michigan State University College of Nursing East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033\u2010295x.84.2.191"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12124"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278\u20106133.23.5.443"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/jop.2014.001406"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1188\/07.ONF.1162\u20101167"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.891"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2007.10.004"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/gnp037"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1062860607307990"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120701593489"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/her\/cyn012"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/mlr.0b013e318032937e"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278\u20106133.21.2.177"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2005.032581"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1188\/02.ONF.949\u2010956"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2008.16.8872"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12160\u2010010\u20109191\u20107"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2011.02.003"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc06\u20101390"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870449908407311"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/09602011.2012.678860"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2010.12.016"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2004.031005"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/dis.2006.9.291"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/dis.2006.9.102"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.1567"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20093"},{"key":"e_1_2_9_29_1","volume-title":"Motivational Interviewing: helping People Change","author":"Miller W.R.","year":"2012"},{"key":"e_1_2_9_30_1","unstructured":"National Cancer Institute.NCI Dictionary of Cancer Terms. 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