{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:50:52Z","timestamp":1789512652701,"version":"build-2803163510"},"reference-count":79,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,10,15]],"date-time":"2015-10-15T00:00:00Z","timestamp":1444867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To develop and psychometrically test a brief self\u2010report to assess the amount of infertility\u2010related stress; to investigate how infertility\u2010related stress was associated to socio\u2010demographics, causes of infertility and emotional distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Infertility exerts a stress effect on both personal and interpersonal areas. Due to the burden of multiple assessments in fertility clinics, there is the need for very brief and easy to administer measures of the stressful impact of infertility on the intrapersonal and interpersonal life domains.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>The study had a psychometric, cross\u2010sectional design.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Between January \u2010 December 2013, a total of 597 Italian infertile patients (58\u00b76% women), recruited at the time of initial infertility consultation, completed the Infertility\u2010Related Stress Scale. A subsample of 200 participants (50% women) also completed self\u2010reports of anxiety and depression. A subsample of 40 patients completed again the Infertility\u2010Related Stress Scale at a 4\u2010week follow\u2010up visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Confirmatory factor analyses supported the proposed two\u2010factor model of infertility stress affecting intrapersonal and interpersonal life domains. Both dimensions showed good reliability and were associated in expected ways with emotional distress. Patients with above\u2010threshold levels of anxiety and depression showed higher infertility stress in both domains and particularly in the intrapersonal area. Infertility stress was significantly higher in women than in men in the intrapersonal domain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The Infertility\u2010Related Stress Scale showed evidence of validity and reliability. 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