{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:09:34Z","timestamp":1787015374840,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T00:00:00Z","timestamp":1468540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006127","name":"Faculty of Health Sciences, Queen's University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006127","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008264","name":"Kingston General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008264","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Advanced Nursing"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To identify factors associated with longitudinal changes in health\u2010related quality of life in community\u2010dwelling individuals with venous or mixed\u2010venous leg ulcers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Most care focuses primarily on healing; this research may additionally lead to strategies to improve quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Data from four studies (2000\u20132009) were combined (2012) to examine quality of life in community\u2010dwelling individuals referred for care of chronic leg wounds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data collection occurred at baseline, 3, 6, 9 and 12\u00a0months or at healing and included a comprehensive clinical assessment and measures of pain (McGill), functional autonomy (\n                      <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\n                      \u20105D\n                      <jats:sup>\u2122<\/jats:sup>\n                      ) and quality of life (\n                      <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\n                      \u201012\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:sup>TM<\/jats:sup>\n                      <\/jats:styled-content>\n                      ). Physical Component Summary and Mental Component Summary scores (\n                      <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\n                      \u201012\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:sup>TM<\/jats:sup>\n                      <\/jats:styled-content>\n                      ) were categorized by whether or not there was an improvement (\u22653 points) over time. Multivariable logistic regression modelling was used to identify factors associated with improvement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results\/findings<\/jats:title>\n                    <jats:p>\n                      Mean age of this sample (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0519) was 67\u00b75\u00a0years, 55\u00b79% were women. Median time to healing was 70\u00a0days. Mean Physical Component Summary score increased from 37\u00b70\u201041\u00b75; factors associated with improvement included independent mobility, family history, problems with usual activities, fewer comorbidities and higher baseline pain. Mean Mental Component Summary score improved from 50\u00b75\u201053\u00b77; factors associated with improvement included anxiety or depression at baseline and living with others.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Chronic leg ulceration has a substantial, negative impact on health\u2010related quality of life. Ascertaining characteristics associated with changes in quality of life will contribute to the development of comprehensive strategies for prevention, care and improved quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jan.13054","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T07:30:18Z","timestamp":1467012618000},"page":"2869-2878","source":"Crossref","is-referenced-by-count":30,"title":["Health\u2010related quality of life at healing in individuals with chronic venous or mixed\u2010venous leg ulceration: a longitudinal assessment"],"prefix":"10.1111","volume":"72","author":[{"given":"Wilma M.","family":"Hopman","sequence":"first","affiliation":[{"name":"Clinical Research Institute Kingston General Hospital Kingston Ontario Canada"},{"name":"Department of Public Health Sciences Queen's University Kingston Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth 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